# ErmineJ results file # Created Sat Apr 27 21:08:31 PDT 2013 # If you use this file in your research, please cite: # Lee H.K., Braynen W., Keshav K. and Pavlidis P. (2005) # ErmineJ: Tool for functional analysis of gene expression data sets. BMC Bioinformatics 6:269 # See http://www.chibi.ubc.ca/ermineJ for more information # Do not edit this file or you may not be able to reload it into ErmineJ. Edit a copy instead. # Start output of analysis run: example # Settings scoreThreshold = 1.0 maxClassSize = 200 minClassSize = 20 rawFile = scoreFile = C:\\Users\\joeblow\\ermineJ.data\\QuickList.example.txt scoreCol = 2 classFile = C:\\Users\\joeblow\\ermineJ.data\\go_daily-termdb.rdf-xml.gz bigIsBetter = false doLog = true geneRepTreatment = MEAN annotFile = C:\\Users\\joeblow\\ermineJ.data\\Generic_human_noParents.an.txt.gz annotFormat = DEFAULT classScoreMethod = ORA multifuncCorr = true useGOMolecularFunction = false useGOBiologicalProcess = true useGOCellularComponent = false useUserDefinedGroups = false customGeneSetFiles = [C:\\Users\\joeblow\\ermineJ.data\\genesets\\kegg.txt] multifunctionalityCorrelation=0.1119 multifunctionalityEnrichment=0.6048 multifunctionalityEnrichmentPvalue=7.353e-09 numAboveThreshold=247 #!---- !# runName=example # #! Name ID NumProbes NumGenes RawScore Pval CorrectedPvalue MFPvalue CorrectedMFPvalue Multifunctionality Same as GeneMembers ! learning or memory GO:0007611 154 154 13.000 2.241E-07 5.079E-04 1.359E-03 0.51355645 0.946 ! cognition GO:0050890 167 167 13.000 5.717E-07 6.48E-04 2.265E-03 0.73354338 0.946 ! regulation of transmission of nerve impulse GO:0051969 200 197 14.000 6.347E-07 4.796E-04 0.05591574 1.000 0.946 ! regulation of ion homeostasis GO:2000021 146 144 12.000 7.574E-07 4.293E-04 0.01495471 0.77050749 0.946 ! regulation of synaptic transmission GO:0050804 176 175 13.000 9.744E-07 4.418E-04 0.09536058 1.000 0.946 ! regulation of action potential GO:0001508 143 141 11.000 4.199E-06 1.586E-03 7.684E-04 0.43550547 0.946 ! regulation of heart contraction GO:0008016 121 121 10.000 6.911E-06 2.238E-03 6.684E-03 0.65876661 0.946 ! regulation of metal ion transport GO:0010959 180 180 12.000 7.838E-06 2.221E-03 0.01262409 0.75312656 0.946 ! positive regulation of synaptic transmission GO:0050806 53 53 7.000 7.855E-06 1.979E-03 1.000 1.000 0.879 ! positive regulation of transmission of nerve impulse GO:0051971 56 56 7.000 1.141E-05 2.587E-03 1.000 1.000 0.881 ! negative regulation of ion transport GO:0043271 38 38 6.000 1.239E-05 2.554E-03 1.663E-04 0.37697304 0.856 ! response to mechanical stimulus GO:0009612 133 133 10.000 1.595E-05 3.014E-03 0.11239589 1.000 0.946 ! positive regulation of neurological system process GO:0031646 64 62 7.000 2.255E-05 3.933E-03 1.000 1.000 0.883 ! response to amphetamine GO:0001975 26 26 5.000 2.494E-05 4.039E-03 5.339E-03 0.63698962 0.845 ! learning GO:0007612 90 90 8.000 3.434E-05 5.189E-03 0.03599506 1.000 0.886 ! memory GO:0007613 67 67 7.000 3.762E-05 5.33E-03 0.06534748 1.000 0.874 ! regulation of synaptic transmission, glutamatergic GO:0051966 30 30 5.000 5.165E-05 6.888E-03 0.34111948 1.000 0.851 ! multicellular organismal response to stress GO:0033555 52 52 6.000 7.777E-05 9.795E-03 5.704E-03 0.61573205 0.868 ! response to temperature stimulus GO:0009266 103 103 8.000 9.032E-05 0.01077604 0.01408973 0.76050981 0.946 ! regulation of G-protein coupled receptor protein signaling pathway GO:0008277 105 105 8.000 1.034E-04 0.01172473 3.355E-03 0.76053583 0.794 ! response to amine stimulus GO:0014075 108 105 8.000 1.034E-04 0.01116641 0.015204 0.76594372 0.946 ! central nervous system neuron development GO:0021954 55 55 6.000 1.07E-04 0.01102508 0.04028556 1.000 0.865 ! associative learning GO:0008306 56 56 6.000 1.185E-04 0.01167625 0.04214618 1.000 0.876 ! regulation of heart rate GO:0002027 57 57 6.000 1.309E-04 0.01236331 0.18572098 1.000 0.884 ! sensory perception of pain GO:0019233 57 57 6.000 1.309E-04 0.01186878 0.04404933 1.000 0.844 ! striated muscle cell differentiation GO:0051146 172 171 10.000 1.35E-04 0.01177049 0.03153344 1.000 0.946 ! regulation of renal sodium excretion GO:0035813 21 21 4.000 1.761E-04 0.0147842 1.000 1.000 0.826 ! response to morphine GO:0043278 21 21 4.000 1.761E-04 0.01425619 0.25321289 1.000 0.770 ! cytosolic calcium ion homeostasis GO:0051480 144 144 9.000 1.771E-04 0.01384161 0.01495471 0.78842627 0.946 ! response to isoquinoline alkaloid GO:0014072 22 22 4.000 2.129E-04 0.01608722 0.2635304 1.000 0.783 ! dopamine metabolic process GO:0042417 22 22 4.000 2.129E-04 0.01556827 0.03654521 1.000 0.820 ! regulation of synaptic plasticity GO:0048167 90 89 7.000 2.305E-04 0.0163306 0.125052 1.000 0.882 ! rhythmic behavior GO:0007622 23 23 4.000 2.549E-04 0.01751277 3.749E-03 0.70819767 0.829 ! regulation of excretion GO:0044062 23 23 4.000 2.549E-04 0.01699769 1.000 1.000 0.834 ! response to organic nitrogen GO:0010243 124 121 8.000 2.764E-04 0.01790153 0.02627637 1.000 0.946 ! cardiac muscle tissue development GO:0048738 122 121 8.000 2.764E-04 0.01740426 0.08669974 1.000 0.946 ! response to alkaloid GO:0043279 92 92 7.000 2.83E-04 0.01734067 0.72243304 1.000 0.890 ! temperature homeostasis GO:0001659 24 24 4.000 3.026E-04 0.01805348 4.241E-03 0.60090129 0.824 ! regulation of synaptic transmission, GABAergic GO:0032228 24 24 4.000 3.026E-04 0.01759057 1.000 1.000 0.802 ! central nervous system neuron differentiation GO:0021953 125 124 8.000 3.264E-04 0.01850012 0.09282819 1.000 0.946 ! regulation of action potential in neuron GO:0019228 97 95 7.000 3.447E-04 0.01906101 3.447E-04 0.39075074 0.946 ! regulation of potassium ion transport GO:0043266 25 25 4.000 3.564E-04 0.0192359 4.771E-03 0.60085048 0.729 ! response to estradiol stimulus GO:0032355 70 70 6.000 4.074E-04 0.02147848 0.07250587 1.000 0.870 ! response to progesterone stimulus GO:0032570 26 26 4.000 4.166E-04 0.02146637 5.339E-03 0.60514014 0.805 ! regulation of muscle system process GO:0090257 129 129 8.000 4.261E-04 0.02146629 0.10348521 1.000 0.946 ! regulation of cardiac muscle contraction GO:0055117 48 48 5.000 5.071E-04 0.024992 4.279E-03 0.57059326 0.881 ! myelination GO:0042552 78 76 6.000 6.342E-04 0.03059021 6.342E-04 0.47924662 0.862 ! aging GO:0007568 174 174 9.000 7.12E-04 0.03362719 0.01062102 0.68793861 0.946 ! feeding behavior GO:0007631 78 78 6.000 7.283E-04 0.03369357 0.09319385 1.000 0.865 ! regulation of catecholamine secretion GO:0050433 30 30 4.000 7.314E-04 0.03316235 0.34111948 1.000 0.856 ! ensheathment of neurons GO:0007272 81 79 6.000 7.792E-04 0.03463484 7.792E-04 0.3532754 0.859 GO:0008366|axon ensheathment, ! axon ensheathment GO:0008366 81 79 6.000 7.792E-04 0.03463484 7.792E-04 0.3532754 0.859 GO:0007272|ensheathment of neurons, ! regulation of muscle contraction GO:0006937 112 112 7.000 9.276E-04 0.04043812 0.06956142 1.000 0.946 ! skeletal system morphogenesis GO:0048705 181 181 9.000 9.423E-04 0.04030707 3.711E-03 0.76484464 0.946 ! fat cell differentiation GO:0045444 82 82 6.000 9.485E-04 0.03981872 0.10435077 1.000 0.946 ! locomotory behavior GO:0007626 146 146 8.000 9.643E-04 0.03974837 0.05199146 1.000 0.946 ! regulation of striated muscle contraction GO:0006942 58 58 5.000 1.214E-03 0.04912839 8.384E-03 0.61311011 0.882 ! developmental growth GO:0048589 191 191 9.000 1.373E-03 0.05460426 0.04950739 1.000 0.946 ! response to heat GO:0009408 60 60 5.000 1.415E-03 0.0552909 0.05001093 1.000 0.799 ! cellular response to inorganic substance GO:0071241 89 89 6.000 1.453E-03 0.05583784 0.03475802 1.000 0.882 ! muscle cell development GO:0055001 122 121 7.000 1.456E-03 0.05502876 0.23389674 1.000 0.946 ! protein autophosphorylation GO:0046777 158 158 8.000 1.6E-03 0.05945719 0.06818317 1.000 0.946 ! catecholamine metabolic process GO:0006584 37 37 4.000 1.634E-03 0.05976434 0.0922175 1.000 0.846 GO:0009712|catechol-containing compound metabolic process, GO:0034311|diol metabolic process, ! catechol-containing compound metabolic process GO:0009712 37 37 4.000 1.634E-03 0.05976434 0.0922175 1.000 0.846 GO:0034311|diol metabolic process, GO:0006584|catecholamine metabolic process, ! diol metabolic process GO:0034311 37 37 4.000 1.634E-03 0.05976434 0.0922175 1.000 0.846 GO:0009712|catechol-containing compound metabolic process, GO:0006584|catecholamine metabolic process, ! muscle fiber development GO:0048747 62 62 5.000 1.639E-03 0.05898214 0.05419214 1.000 0.849 ! response to estrogen stimulus GO:0043627 124 124 7.000 1.677E-03 0.05940434 0.09282819 1.000 0.946 ! regulation of calcium ion transport GO:0051924 126 126 7.000 1.838E-03 0.06410367 0.25229087 1.000 0.946 ! response to organic cyclic compound GO:0014070 162 162 8.000 1.873E-03 0.06433793 0.8957923 1.000 0.946 ! regulation of neuronal synaptic plasticity GO:0048168 40 39 4.000 1.992E-03 0.06740785 0.1008138 1.000 0.809 ! cytosolic calcium ion transport GO:0060401 39 39 4.000 1.992E-03 0.06641656 0.01646118 0.81124991 0.848 ! skeletal muscle tissue development GO:0007519 130 128 7.000 2.011E-03 0.06606096 0.03240443 1.000 0.946 ! regulation of fat cell differentiation GO:0045598 67 65 5.000 2.024E-03 0.06553282 0.01241829 0.78200721 0.853 ! regulation of phospholipase activity GO:0010517 129 129 7.000 2.102E-03 0.06710306 0.53369805 1.000 0.946 ! labyrinthine layer development GO:0060711 40 40 4.000 2.19E-03 0.06895069 0.10519251 1.000 0.777 ! elevation of cytosolic calcium ion concentration GO:0007204 130 130 7.000 2.196E-03 0.06818579 0.10568138 1.000 0.946 ! regulation of smooth muscle cell proliferation GO:0048660 67 67 5.000 2.314E-03 0.07088582 0.60652916 1.000 0.886 ! regulation of osteoblast differentiation GO:0045667 98 98 6.000 2.376E-03 0.0718168 0.0467995 1.000 0.946 ! ventricular cardiac muscle tissue morphogenesis GO:0055010 41 41 4.000 2.401E-03 0.07160941 0.4346826 1.000 0.863 ! ventricular cardiac muscle cell differentiation GO:0055012 20 20 3.000 2.488E-03 0.07324251 0.24275143 1.000 0.805 ! neuron-neuron synaptic transmission GO:0007270 42 42 4.000 2.625E-03 0.07629348 0.44250169 1.000 0.824 ! visual behavior GO:0007632 42 42 4.000 2.625E-03 0.07532774 0.02006545 0.94767459 0.832 ! regulation of vasoconstriction GO:0019229 42 42 4.000 2.625E-03 0.07438615 0.1140997 1.000 0.861 ! diencephalon development GO:0021536 69 69 5.000 2.633E-03 0.07370333 0.07008199 1.000 0.884 ! skeletal muscle organ development GO:0060538 137 135 7.000 2.716E-03 0.0750805 0.03935709 1.000 0.946 ! neurotransmitter transport GO:0006836 101 101 6.000 2.765E-03 0.07551241 0.01303174 0.75751168 0.946 ! rhythmic process GO:0048511 173 173 8.000 2.817E-03 0.07603461 0.01031116 0.68751177 0.946 ! cyclic nucleotide metabolic process GO:0009187 43 43 4.000 2.863E-03 0.07636631 0.02135561 0.94927791 0.832 ! cardiac septum morphogenesis GO:0060411 43 43 4.000 2.863E-03 0.07547833 0.45021307 1.000 0.878 ! response to mineralocorticoid stimulus GO:0051385 21 21 3.000 2.873E-03 0.0748631 2.873E-03 0.81413622 0.780 ! regulation of neurotransmitter levels GO:0001505 102 102 6.000 2.904E-03 0.07481826 0.01355377 0.74942454 0.946 ! ventricular cardiac muscle tissue development GO:0003229 44 44 4.000 3.116E-03 0.07937074 0.45781821 1.000 0.865 ! smooth muscle contraction GO:0006939 44 44 4.000 3.116E-03 0.07848884 0.12319207 1.000 0.849 ! regulation of gluconeogenesis GO:0006111 22 22 3.000 3.293E-03 0.08203593 3.293E-03 0.82947442 0.708 ! neuroblast proliferation GO:0007405 22 22 3.000 3.293E-03 0.08114424 0.03654521 1.000 0.763 ! long-term memory GO:0007616 22 22 3.000 3.293E-03 0.08027172 1.000 1.000 0.750 ! cellular response to heat GO:0034605 22 22 3.000 3.293E-03 0.07941776 0.03654521 1.000 0.393 ! response to fatty acid GO:0070542 22 22 3.000 3.293E-03 0.07858179 0.2635304 1.000 0.779 ! cranial nerve development GO:0021545 45 45 4.000 3.384E-03 0.07990005 0.46531857 1.000 0.862 ! regulation of endothelial cell migration GO:0010594 74 74 5.000 3.571E-03 0.0834529 0.27208382 1.000 0.886 ! regulation of amine transport GO:0051952 46 46 4.000 3.666E-03 0.08480904 0.47271558 1.000 0.882 ! response to vitamin GO:0033273 143 143 7.000 3.739E-03 0.08561016 0.04833666 1.000 0.946 ! neurotransmitter metabolic process GO:0042133 23 23 3.000 3.749E-03 0.08498372 3.749E-03 0.65372093 0.731 ! positive regulation of vasodilation GO:0045909 23 23 3.000 3.749E-03 0.0841423 0.03966869 1.000 0.835 ! reactive oxygen species metabolic process GO:0072593 75 75 5.000 3.784E-03 0.08409279 3.784E-03 0.61267605 0.871 ! skeletal muscle fiber development GO:0048741 47 47 4.000 3.965E-03 0.08725774 0.02696057 1.000 0.817 ! regulation of neuron apoptosis GO:0043523 147 146 7.000 4.189E-03 0.09132229 0.32733885 1.000 0.946 ! transcription initiation from RNA polymerase II promoter GO:0006367 185 185 8.000 4.233E-03 0.09139983 4.233E-03 0.63979884 0.946 ! cardiac atrium morphogenesis GO:0003209 24 24 3.000 4.241E-03 0.09070208 0.28374143 1.000 0.846 ! cellular response to metal ion GO:0071248 79 79 5.000 4.726E-03 0.10013887 0.09593458 1.000 0.876 ! protein export from nucleus GO:0006611 25 25 3.000 4.771E-03 0.10014175 0.04620405 1.000 0.489 ! dopamine receptor signaling pathway GO:0007212 26 25 3.000 4.771E-03 0.09922302 0.04620405 1.000 0.706 ! regulation of fibroblast growth factor receptor signaling pathway GO:0040036 25 25 3.000 4.771E-03 0.09832099 0.04620405 1.000 0.796 ! positive regulation of muscle contraction GO:0045933 25 25 3.000 4.771E-03 0.09743521 0.29363883 1.000 0.827 ! response to corticosteroid stimulus GO:0031960 113 113 6.000 4.81E-03 0.09736001 0.07137113 1.000 0.946 ! muscle contraction GO:0006936 194 193 8.000 5.446E-03 0.10925531 0.12924889 1.000 0.946 ! regulation of ERK1 and ERK2 cascade GO:0070372 117 116 6.000 5.46E-03 0.10858198 0.47728336 1.000 0.946 ! phosphatidylinositol metabolic process GO:0046488 117 117 6.000 5.691E-03 0.11217923 0.02313462 1.000 0.946 ! cardiac atrium development GO:0003230 27 27 3.000 5.946E-03 0.11619437 0.31302682 1.000 0.857 ! central nervous system neuron axonogenesis GO:0021955 27 27 3.000 5.946E-03 0.11520125 0.05310261 1.000 0.801 ! platelet-derived growth factor receptor signaling pathway GO:0048008 27 27 3.000 5.946E-03 0.11422497 5.946E-03 0.61266121 0.730 ! response to pain GO:0048265 27 27 3.000 5.946E-03 0.1132651 0.31302682 1.000 0.801 ! positive regulation of stress fiber assembly GO:0051496 27 27 3.000 5.946E-03 0.11232122 0.31302682 1.000 0.759 ! regulation of cardiac muscle cell proliferation GO:0060043 27 27 3.000 5.946E-03 0.11139295 1.000 1.000 0.851 ! regulation of lipase activity GO:0060191 156 156 7.000 5.994E-03 0.11137347 0.63701894 1.000 0.946 ! cardiac muscle tissue morphogenesis GO:0055008 53 53 4.000 6.104E-03 0.11249744 0.5217178 1.000 0.879 ! regulation of ossification GO:0030278 157 157 7.000 6.202E-03 0.11337961 0.06673807 1.000 0.946 ! regulation of angiogenesis GO:0045765 157 157 7.000 6.202E-03 0.11247257 0.368792 1.000 0.946 ! regulation of calcium ion transport into cytosol GO:0010522 54 54 4.000 6.522E-03 0.11734379 0.17087211 1.000 0.881 ! cAMP metabolic process GO:0046058 28 28 3.000 6.592E-03 0.1176698 0.05668035 1.000 0.758 ! organ formation GO:0048645 28 28 3.000 6.592E-03 0.11675051 0.32252113 1.000 0.835 ! negative regulation of synaptic transmission GO:0050805 28 28 3.000 6.592E-03 0.11584546 0.32252113 1.000 0.812 ! placenta blood vessel development GO:0060674 28 28 3.000 6.592E-03 0.11495435 0.05668035 1.000 0.747 ! cardiac cell differentiation GO:0035051 87 86 5.000 6.759E-03 0.1169739 0.33320414 1.000 0.890 ! regulation of cell division GO:0051302 89 87 5.000 7.093E-03 0.12181329 0.03235938 1.000 0.946 ! response to calcium ion GO:0051592 87 87 5.000 7.093E-03 0.1208974 7.093E-03 0.66997309 0.946 ! positive regulation of phospholipase activity GO:0010518 123 123 6.000 7.225E-03 0.12222506 0.50817827 1.000 0.946 ! positive regulation of epithelial cell differentiation GO:0030858 29 29 3.000 7.279E-03 0.1222279 7.279E-03 0.66003068 0.838 ! release of sequestered calcium ion into cytosol GO:0051209 29 29 3.000 7.279E-03 0.12132917 0.06033973 1.000 0.833 GO:0051283|negative regulation of sequestering of calcium ion, ! negative regulation of sequestering of calcium ion GO:0051283 29 29 3.000 7.279E-03 0.12132917 0.06033973 1.000 0.833 GO:0051209|release of sequestered calcium ion into cytosol, ! endoderm development GO:0007492 56 56 4.000 7.414E-03 0.12269089 7.414E-03 0.64648661 0.868 ! positive regulation of osteoblast differentiation GO:0045669 56 56 4.000 7.414E-03 0.12180183 7.414E-03 0.62254267 0.871 ! eye morphogenesis GO:0048592 125 125 6.000 7.797E-03 0.12715781 7.797E-03 0.63124771 0.946 ! cardiac septum development GO:0003279 57 57 4.000 7.889E-03 0.1277526 0.54765419 1.000 0.881 ! phenol-containing compound metabolic process GO:0018958 57 57 4.000 7.889E-03 0.12684655 0.18572098 1.000 0.863 ! negative regulation of fat cell differentiation GO:0045599 30 30 3.000 8.006E-03 0.12781655 8.006E-03 0.62586035 0.840 ! regulation of sequestering of calcium ion GO:0051282 30 30 3.000 8.006E-03 0.12692273 0.06407785 1.000 0.837 ! regulation of cardiac muscle tissue growth GO:0055021 30 30 3.000 8.006E-03 0.12604132 1.000 1.000 0.863 ! cellular response to calcium ion GO:0071277 30 30 3.000 8.006E-03 0.12517207 8.006E-03 0.60499834 0.765 ! regulation of cardiac muscle cell membrane potential GO:0086036 30 30 3.000 8.006E-03 0.12431473 0.06407785 1.000 0.816 ! post-embryonic development GO:0009791 91 90 5.000 8.162E-03 0.12586627 0.12812293 1.000 0.946 ! positive regulation of neuron projection development GO:0010976 59 58 4.000 8.384E-03 0.12842171 0.1907112 1.000 0.853 ! cardiac ventricle development GO:0003231 91 91 5.000 8.541E-03 0.12995508 0.35828393 1.000 0.890 ! mating GO:0007618 31 31 3.000 8.775E-03 0.13261869 0.35022707 1.000 0.778 ! positive regulation of actin filament bundle assembly GO:0032233 31 31 3.000 8.775E-03 0.13174043 0.35022707 1.000 0.773 ! response to nicotine GO:0035094 31 31 3.000 8.775E-03 0.13087371 1.000 1.000 0.833 ! muscle tissue morphogenesis GO:0060415 59 59 4.000 8.898E-03 0.13184647 0.56009216 1.000 0.880 ! ureteric bud development GO:0001657 93 93 5.000 9.337E-03 0.13745251 0.03985745 1.000 0.889 ! striated muscle cell development GO:0055002 94 93 5.000 9.337E-03 0.13656572 0.1374941 1.000 0.946 ! cellular biogenic amine metabolic process GO:0006576 130 130 6.000 9.368E-03 0.13614345 0.10568138 1.000 0.946 ! response to cold GO:0009409 32 32 3.000 9.586E-03 0.13841028 9.586E-03 0.67907543 0.751 ! negative regulation of transmission of nerve impulse GO:0051970 32 32 3.000 9.586E-03 0.13753426 0.35920926 1.000 0.831 ! positive regulation of lipase activity GO:0060193 131 131 6.000 9.708E-03 0.13841705 0.54200197 1.000 0.946 ! regulation of carbohydrate biosynthetic process GO:0043255 61 61 4.000 9.988E-03 0.1415161 0.05208108 1.000 0.875 ! regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043281 173 172 7.000 0.01000794 0.14091928 0.21420689 1.000 0.946 ! phosphatidylinositol biosynthetic process GO:0006661 95 95 5.000 0.01018293 0.1424982 0.01018293 0.69953663 0.946 ! regulation of lipid biosynthetic process GO:0046890 95 95 5.000 0.01018293 0.14162398 0.04255857 1.000 0.890 ! bone development GO:0060348 95 95 5.000 0.01018293 0.14076042 0.04255857 1.000 0.946 ! placenta development GO:0001890 133 133 6.000 0.01041355 0.1430759 0.5502032 1.000 0.946 ! regulation of vasodilation GO:0042312 33 33 3.000 0.01043836 0.14255279 0.07573638 1.000 0.861 ! cardiac ventricle morphogenesis GO:0003208 62 62 4.000 0.01056368 0.1434004 0.5781133 1.000 0.885 ! negative regulation of neuron apoptosis GO:0043524 96 96 5.000 0.01062482 0.14337177 0.73751728 1.000 0.946 ! nuclear export GO:0051168 97 97 5.000 0.01107964 0.14862456 0.04536065 1.000 0.724 ! peptidyl-tyrosine phosphorylation GO:0018108 63 63 4.000 0.01116049 0.14882847 0.21590143 1.000 0.863 ! cardiac muscle cell differentiation GO:0055007 63 63 4.000 0.01116049 0.14795813 0.21590143 1.000 0.885 ! neuromuscular junction development GO:0007528 34 34 3.000 0.0113338 0.14938218 0.07976154 1.000 0.760 ! response to toxin GO:0009636 98 98 5.000 0.01154758 0.15132007 0.15360764 1.000 0.946 ! response to lipid GO:0033993 64 64 4.000 0.01177861 0.15346039 0.22097776 1.000 0.884 ! cardiac chamber morphogenesis GO:0003206 99 99 5.000 0.0120288 0.15582458 0.39765904 1.000 0.891 ! cardiac muscle contraction GO:0060048 35 35 3.000 0.01227222 0.15807457 0.0838518 1.000 0.827 ! regulation of heart growth GO:0060420 35 35 3.000 0.01227222 0.15718149 1.000 1.000 0.872 ! peptidyl-tyrosine modification GO:0018212 65 65 4.000 0.01241829 0.15815876 0.22606381 1.000 0.865 ! nerve development GO:0021675 65 65 4.000 0.01241829 0.15727519 0.59539905 1.000 0.877 ! muscle organ morphogenesis GO:0048644 65 65 4.000 0.01241829 0.15640144 0.59539905 1.000 0.881 ! female sex differentiation GO:0046660 100 100 5.000 0.01252347 0.15685473 0.01252347 0.76731639 0.946 ! regulation of cysteine-type endopeptidase activity GO:2000116 181 180 7.000 0.01262409 0.1572462 0.2376485 1.000 0.946 ! positive regulation of cytoskeleton organization GO:0051495 102 101 5.000 0.01303174 0.16143691 0.40733226 1.000 0.946 ! vasculogenesis GO:0001570 66 66 4.000 0.01307978 0.16115144 0.23115838 1.000 0.875 ! regulation of organ growth GO:0046620 66 66 4.000 0.01307978 0.16028035 1.000 1.000 0.886 ! eye photoreceptor cell differentiation GO:0001754 36 36 3.000 0.01325392 0.161541 0.01325392 0.75116566 0.799 ! positive regulation of apoptotic signaling pathway GO:2001235 36 36 3.000 0.01325392 0.16067715 0.08800462 1.000 0.808 ! negative regulation of locomotion GO:0040013 143 142 6.000 0.0140422 0.16932805 0.58582364 1.000 0.946 ! synapse organization GO:0050808 103 103 5.000 0.01408973 0.16900218 0.41693014 1.000 0.946 ! visual learning GO:0008542 37 37 3.000 0.01427916 0.17037291 0.0922175 1.000 0.834 ! benzene-containing compound metabolic process GO:0042537 68 68 4.000 0.01446917 0.17173618 0.24136827 1.000 0.876 ! bone morphogenesis GO:0060349 68 68 4.000 0.01446917 0.17084172 0.06769571 1.000 0.867 ! regulation of striated muscle tissue development GO:0016202 105 104 5.000 0.01463975 0.1719602 0.42169982 1.000 0.891 ! ossification GO:0001503 186 186 7.000 0.01488606 0.17395202 0.11547674 1.000 0.946 ! regulation of muscle organ development GO:0048634 106 105 5.000 0.015204 0.17675624 0.42644951 1.000 0.946 ! MAPK cascade GO:0000165 187 187 7.000 0.01528939 0.17684202 0.11739921 1.000 0.946 ! regulation of release of sequestered calcium ion into cytosol GO:0051279 38 38 3.000 0.01534818 0.17662096 0.41056392 1.000 0.861 ! calcium ion transport into cytosol GO:0060402 38 38 3.000 0.01534818 0.17572893 0.09648802 1.000 0.844 ! circadian rhythm GO:0007623 70 70 4.000 0.01594861 0.18168589 0.07250587 1.000 0.836 ! adult locomotory behavior GO:0008344 70 70 4.000 0.01594861 0.18077746 0.25159822 1.000 0.853 ! positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 107 107 5.000 0.01637574 0.18469558 0.06087636 1.000 0.946 ! response to glucocorticoid stimulus GO:0051384 107 107 5.000 0.01637574 0.18378124 0.18397556 1.000 0.946 ! negative regulation of neurological system process GO:0031645 39 39 3.000 0.01646118 0.18383003 0.41871524 1.000 0.855 ! positive regulation of smooth muscle cell proliferation GO:0048661 39 39 3.000 0.01646118 0.1829289 0.41871524 1.000 0.868 ! regulation of stress fiber assembly GO:0051492 39 39 3.000 0.01646118 0.18203657 0.41871524 1.000 0.817 ! regulation of neurotransmitter transport GO:0051588 39 39 3.000 0.01646118 0.18115289 1.000 1.000 0.822 ! regulation of excitatory postsynaptic membrane potential GO:0060079 39 39 3.000 0.01646118 0.18027776 0.41871524 1.000 0.864 ! regulation of developmental growth GO:0048638 108 108 5.000 0.01698353 0.1851041 0.44057508 1.000 0.946 ! negative regulation of protein phosphorylation GO:0001933 72 72 4.000 0.01751978 0.19003509 0.63303832 1.000 0.880 ! adult behavior GO:0030534 109 109 5.000 0.0176061 0.19006202 0.19093031 1.000 0.946 ! ventricular septum development GO:0003281 40 40 3.000 0.01761831 0.18929249 0.42675429 1.000 0.864 ! response to axon injury GO:0048678 40 40 3.000 0.01761831 0.1883996 1.000 1.000 0.817 ! positive regulation of cell cycle GO:0045787 111 110 5.000 0.0182436 0.1941701 0.19443262 1.000 0.946 ! regulation of muscle cell differentiation GO:0051147 111 110 5.000 0.0182436 0.19326277 0.19443262 1.000 0.946 ! positive regulation of cysteine-type endopeptidase activity GO:2001056 110 110 5.000 0.0182436 0.19236387 0.06601437 1.000 0.946 ! regulation of cardiac muscle tissue development GO:0055024 41 41 3.000 0.01881971 0.19751979 1.000 1.000 0.878 ! response to carbohydrate stimulus GO:0009743 111 111 5.000 0.01889615 0.19740817 0.19795087 1.000 0.946 ! regulation of cyclase activity GO:0031279 111 111 5.000 0.01889615 0.19650263 0.45450861 1.000 0.946 ! neurotransmitter secretion GO:0007269 74 74 4.000 0.01918422 0.19858731 0.01918422 0.92533236 0.818 ! cell maturation GO:0048469 112 112 5.000 0.01956389 0.201597 0.06956142 1.000 0.946 ! positive regulation of hormone secretion GO:0046887 75 75 4.000 0.02005186 0.20569031 1.000 1.000 0.886 ! heart process GO:0003015 42 42 3.000 0.02006545 0.20490261 0.1140997 1.000 0.847 GO:0060047|heart contraction, ! anterior/posterior axis specification GO:0009948 42 42 3.000 0.02006545 0.20398377 0.1140997 1.000 0.852 ! photoreceptor cell differentiation GO:0046530 42 42 3.000 0.02006545 0.20307313 0.02006545 0.92833429 0.809 ! heart contraction GO:0060047 42 42 3.000 0.02006545 0.20490261 0.1140997 1.000 0.847 GO:0003015|heart process, ! cardiac chamber development GO:0003205 113 113 5.000 0.02024694 0.20399917 0.46368699 1.000 0.946 ! negative regulation of sequence-specific DNA binding transcription factor activity GO:0043433 113 113 5.000 0.02024694 0.20309652 0.07137113 1.000 0.946 ! positive regulation of cell development GO:0010720 156 155 6.000 0.02071722 0.20689839 0.16688735 1.000 0.946 ! negative regulation of MAPK cascade GO:0043409 76 76 4.000 0.02094333 0.20823912 0.08781253 1.000 0.860 ! response to reactive oxygen species GO:0000302 114 114 5.000 0.02094542 0.20735052 0.02094542 0.94966537 0.946 ! mesenchymal cell differentiation GO:0048762 114 114 5.000 0.02094542 0.20644899 0.46824219 1.000 0.946 ! regulation of lyase activity GO:0051339 114 114 5.000 0.02094542 0.20555527 0.46824219 1.000 0.946 ! positive regulation of endopeptidase activity GO:0010950 115 115 5.000 0.02165945 0.21164644 0.07506228 1.000 0.946 ! developmental maturation GO:0021700 157 157 6.000 0.02190634 0.21314025 0.1722486 1.000 0.946 ! positive regulation of endothelial cell migration GO:0010595 44 44 3.000 0.02269022 0.2198236 0.12319207 1.000 0.868 ! regulation of actin filament bundle assembly GO:0032231 44 44 3.000 0.02269022 0.21888818 0.45781821 1.000 0.833 ! regulation of postsynaptic membrane potential GO:0060078 44 44 3.000 0.02269022 0.21796069 0.45781821 1.000 0.873 ! peripheral nervous system development GO:0007422 78 78 4.000 0.02279835 0.21807539 0.29255074 1.000 0.860 ! positive regulation of peptidase activity GO:0010952 119 119 5.000 0.02467331 0.23501849 0.08272776 1.000 0.946 ! regulation of cellular ketone metabolic process GO:0010565 162 162 6.000 0.02507872 0.23788058 0.18590678 1.000 0.946 ! regulation of sodium ion transport GO:0002028 46 46 3.000 0.02549274 0.24080015 0.47271558 1.000 0.850 ! cellular biogenic amine biosynthetic process GO:0042401 46 46 3.000 0.02549274 0.23980098 0.13245288 1.000 0.842 ! negative regulation of intracellular protein kinase cascade GO:0010741 121 121 5.000 0.02627637 0.24615091 0.23389674 1.000 0.946 ! embryonic placenta development GO:0001892 82 82 4.000 0.02680045 0.25002729 0.31294132 1.000 0.869 ! regulation of smoothened signaling pathway GO:0008589 47 47 3.000 0.02696057 0.25049023 0.13714142 1.000 0.804 ! vascular process in circulatory system GO:0003018 83 83 4.000 0.02786249 0.25781332 0.31802088 1.000 0.889 ! neuromuscular process GO:0050905 83 83 4.000 0.02786249 0.2567653 0.31802088 1.000 0.875 ! developmental growth involved in morphogenesis GO:0060560 83 83 4.000 0.02786249 0.25572576 0.10721908 1.000 0.888 ! autonomic nervous system development GO:0048483 48 48 3.000 0.02847269 0.26027252 0.14186615 1.000 0.869 ! regulation of cartilage development GO:0061035 48 48 3.000 0.02847269 0.25922725 0.02847269 1.000 0.848 ! positive regulation of cell adhesion GO:0045785 125 124 5.000 0.02880328 0.2611881 0.09282819 1.000 0.946 ! response to hydrogen peroxide GO:0042542 84 84 4.000 0.02894932 0.26146659 0.02894932 1.000 0.884 ! outflow tract morphogenesis GO:0003151 49 49 3.000 0.03002898 0.27014168 1.000 1.000 0.887 ! female gamete generation GO:0007292 86 85 4.000 0.03006103 0.26936112 0.328153 1.000 0.946 ! detection of abiotic stimulus GO:0009582 85 85 4.000 0.03006103 0.26830064 0.69392921 1.000 0.946 ! positive regulation of smooth muscle contraction GO:0045987 20 20 2.000 0.03060331 0.2720694 1.000 1.000 0.787 ! mesenchyme morphogenesis GO:0072132 20 20 2.000 0.03060331 0.27100663 0.24275143 1.000 0.862 ! endocrine system development GO:0035270 127 127 5.000 0.03147905 0.27767711 0.25599572 1.000 0.946 ! neural precursor cell proliferation GO:0061351 50 50 3.000 0.03162932 0.27792121 0.15141667 1.000 0.841 ! cyclic nucleotide biosynthetic process GO:0009190 21 21 2.000 0.03352229 0.29341708 0.25321289 1.000 0.747 ! cranial nerve morphogenesis GO:0021602 21 21 2.000 0.03352229 0.29228856 0.25321289 1.000 0.809 ! central nervous system projection neuron axonogenesis GO:0021952 21 21 2.000 0.03352229 0.29116868 0.03352229 1.000 0.743 ! circadian behavior GO:0048512 21 21 2.000 0.03352229 0.29005735 0.25321289 1.000 0.818 ! negative regulation of protein kinase B signaling cascade GO:0051898 21 21 2.000 0.03352229 0.28895447 1.000 1.000 0.789 ! positive regulation of ERK1 and ERK2 cascade GO:0070374 89 88 4.000 0.03354614 0.28806475 0.70648566 1.000 0.888 ! negative regulation of endopeptidase activity GO:0010951 132 130 5.000 0.03430577 0.29347617 0.5378628 1.000 0.946 ! positive regulation of angiogenesis GO:0045766 89 89 4.000 0.03475802 0.29622716 0.71055607 1.000 0.882 ! heart morphogenesis GO:0003007 176 176 6.000 0.03554816 0.3018265 0.70139091 1.000 0.946 ! regulation of mitosis GO:0007088 90 90 4.000 0.03599506 0.3044806 0.35329353 1.000 0.946 GO:0051783|regulation of nuclear division, ! neuropeptide signaling pathway GO:0007218 91 90 4.000 0.03599506 0.3033487 0.12812293 1.000 0.0572 ! regeneration GO:0031099 90 90 4.000 0.03599506 0.30222519 0.35329353 1.000 0.946 ! phosphatidylinositol-mediated signaling GO:0048015 90 90 4.000 0.03599506 0.30110997 0.12812293 1.000 0.946 GO:0048017|inositol lipid-mediated signaling, ! inositol lipid-mediated signaling GO:0048017 90 90 4.000 0.03599506 0.30110997 0.12812293 1.000 0.946 GO:0048015|phosphatidylinositol-mediated signaling, ! regulation of nuclear division GO:0051783 90 90 4.000 0.03599506 0.3044806 0.35329353 1.000 0.946 GO:0007088|regulation of mitosis, ! regulation of the force of heart contraction GO:0002026 22 22 2.000 0.03654521 0.30458824 0.03654521 1.000 0.813 ! positive regulation of acute inflammatory response GO:0002675 22 22 2.000 0.03654521 0.30347253 1.000 1.000 0.841 ! regulation of epithelial cell migration GO:0010632 22 22 2.000 0.03654521 0.30236496 1.000 1.000 0.810 ! eating behavior GO:0042755 22 22 2.000 0.03654521 0.30126545 1.000 1.000 0.732 ! multicellular organismal movement GO:0050879 22 22 2.000 0.03654521 0.30017391 0.03654521 1.000 0.648 GO:0050881|musculoskeletal movement, ! musculoskeletal movement GO:0050881 22 22 2.000 0.03654521 0.30017391 0.03654521 1.000 0.648 GO:0050879|multicellular organismal movement, ! epithelial tube branching involved in lung morphogenesis GO:0060441 22 22 2.000 0.03654521 0.29909025 0.2635304 1.000 0.806 ! adipose tissue development GO:0060612 22 22 2.000 0.03654521 0.29801439 0.03654521 1.000 0.765 ! multicellular organism growth GO:0035264 53 53 3.000 0.03669297 0.2981468 0.16596825 1.000 0.799 ! oogenesis GO:0048477 53 53 3.000 0.03669297 0.29708199 0.16596825 1.000 0.807 ! regulation of apoptotic signaling pathway GO:2001233 53 53 3.000 0.03669297 0.29602476 0.16596825 1.000 0.848 ! response to ethanol GO:0045471 91 91 4.000 0.0372573 0.29951168 0.71852899 1.000 0.889 ! negative regulation of peptidase activity GO:0010466 136 133 5.000 0.03728521 0.29867693 0.5502032 1.000 0.946 ! nucleoside monophosphate metabolic process GO:0009123 93 92 4.000 0.03854476 0.30767944 0.13434453 1.000 0.887 ! response to hexose stimulus GO:0009746 92 92 4.000 0.03854476 0.30659987 0.36326036 1.000 0.888 GO:0034284|response to monosaccharide stimulus, ! response to retinoic acid GO:0032526 92 92 4.000 0.03854476 0.30552784 0.13434453 1.000 0.946 ! response to monosaccharide stimulus GO:0034284 92 92 4.000 0.03854476 0.30659987 0.36326036 1.000 0.888 GO:0009746|response to hexose stimulus, ! camera-type eye morphogenesis GO:0048593 92 92 4.000 0.03854476 0.30446328 0.03854476 1.000 0.946 ! nucleoside monophosphate catabolic process GO:0009125 24 23 2.000 0.03966869 0.31225318 0.03966869 1.000 0.703 ! regulation of vascular endothelial growth factor production GO:0010574 23 23 2.000 0.03966869 0.31117272 1.000 1.000 0.836 ! fear response GO:0042596 23 23 2.000 0.03966869 0.31009971 0.03966869 1.000 0.770 ! regulation of cardiac muscle cell contraction GO:0086004 23 23 2.000 0.03966869 0.30903408 0.03966869 1.000 0.807 ! negative regulation of phosphorylation GO:0042326 93 93 4.000 0.03985745 0.30944123 0.72628316 1.000 0.886 ! development of primary female sexual characteristics GO:0046545 93 93 4.000 0.03985745 0.30838512 0.03985745 1.000 0.946 ! regulation of phosphatidylinositol 3-kinase cascade GO:0014066 55 55 3.000 0.04028556 0.31063726 0.53486601 1.000 0.876 ! negative regulation of angiogenesis GO:0016525 55 55 3.000 0.04028556 0.30958426 0.17579991 1.000 0.808 ! positive regulation of cell projection organization GO:0031346 139 136 5.000 0.04041886 0.3095593 0.289628 1.000 0.946 ! nuclear import GO:0051170 94 94 4.000 0.04119539 0.31444427 0.14066878 1.000 0.946 ! mesenchyme development GO:0060485 138 138 5.000 0.04259424 0.32403068 0.57025315 1.000 0.946 ! heart valve morphogenesis GO:0003179 24 24 2.000 0.04288938 0.32518473 0.28374143 1.000 0.855 ! glutamine family amino acid catabolic process GO:0009065 24 24 2.000 0.04288938 0.32410078 0.04288938 1.000 0.814 ! negative regulation of microtubule polymerization or depolymerization GO:0031111 24 24 2.000 0.04288938 0.32302404 1.000 1.000 0.698 ! positive regulation of interleukin-12 production GO:0032735 24 24 2.000 0.04288938 0.32195442 0.28374143 1.000 0.847 ! regulation of long-term neuronal synaptic plasticity GO:0048169 24 24 2.000 0.04288938 0.32089186 1.000 1.000 0.763 ! kidney development GO:0001822 185 185 6.000 0.04357358 0.32493854 0.04357358 1.000 0.946 ! neutral lipid metabolic process GO:0006638 96 96 4.000 0.043947 0.32664867 0.14709128 1.000 0.946 ! receptor-mediated endocytosis GO:0006898 96 96 4.000 0.043947 0.32558119 0.38301536 1.000 0.946 ! neuron fate commitment GO:0048663 57 57 3.000 0.04404933 0.32527636 0.18572098 1.000 0.864 ! behavioral interaction between organisms GO:0051705 57 57 3.000 0.04404933 0.32422027 0.18572098 1.000 0.858 ! regulation of blood pressure GO:0008217 140 140 5.000 0.04483899 0.32896436 0.85815951 1.000 0.946 ! neuron migration GO:0001764 97 97 4.000 0.04536065 0.33171803 0.15033801 1.000 0.946 ! calcium ion transport GO:0006816 141 141 5.000 0.04598745 0.33522041 0.13118821 1.000 0.946 ! activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger GO:0007200 58 58 3.000 0.04599472 0.33419881 0.55391634 1.000 0.854 ! negative regulation of NF-kappaB transcription factor activity GO:0032088 58 58 3.000 0.04599472 0.33313108 0.1907112 1.000 0.833 ! monovalent inorganic cation homeostasis GO:0055067 58 58 3.000 0.04599472 0.33207016 0.04599472 1.000 0.843 ! maternal placenta development GO:0001893 25 25 2.000 0.04620405 0.33252246 0.29363883 1.000 0.707 ! DNA fragmentation involved in apoptotic nuclear change GO:0006309 25 25 2.000 0.04620405 0.33147018 0.04620405 1.000 0.659 ! endosome organization GO:0007032 25 25 2.000 0.04620405 0.33042453 0.04620405 1.000 0.413 ! regulation of ATPase activity GO:0043462 25 25 2.000 0.04620405 0.32938546 0.04620405 1.000 0.696 ! regulation of digestive system process GO:0044058 25 25 2.000 0.04620405 0.3283529 1.000 1.000 0.835 ! negative regulation of phosphorus metabolic process GO:0010563 98 98 4.000 0.0467995 0.33154522 0.74475036 1.000 0.946 GO:0045936|negative regulation of phosphate metabolic process, ! negative regulation of phosphate metabolic process GO:0045936 98 98 4.000 0.0467995 0.33154522 0.74475036 1.000 0.946 GO:0010563|negative regulation of phosphorus metabolic process, ! regulation of cyclic nucleotide biosynthetic process GO:0030802 142 142 5.000 0.04715333 0.33301124 0.58582364 1.000 0.946 ! glycerophospholipid biosynthetic process GO:0046474 189 189 6.000 0.04747699 0.3342557 0.04747699 1.000 0.946 ! striated muscle contraction GO:0006941 60 59 3.000 0.04798203 0.33676549 0.19571924 1.000 0.846 ! regulation of blood vessel size GO:0050880 59 59 3.000 0.04798203 0.33572609 0.19571924 1.000 0.880 ! regulation of hormone secretion GO:0046883 191 191 6.000 0.04950739 0.34533308 0.74323279 1.000 0.946 ! inactivation of MAPK activity GO:0000188 26 26 2.000 0.04960949 0.34498382 0.04960949 1.000 0.496 ! DNA catabolic process, endonucleolytic GO:0000737 26 26 2.000 0.04960949 0.34392882 0.04960949 1.000 0.679 ! heart valve development GO:0003170 26 26 2.000 0.04960949 0.34288026 0.3034 1.000 0.862 ! regulation of smooth muscle cell migration GO:0014910 26 26 2.000 0.04960949 0.34183807 1.000 1.000 0.844 ! negative regulation of homeostatic process GO:0032845 26 26 2.000 0.04960949 0.34080219 0.04960949 1.000 0.836 ! embryonic pattern specification GO:0009880 60 60 3.000 0.05001093 0.34252198 0.20074367 1.000 0.859 ! regulation of tube size GO:0035150 60 60 3.000 0.05001093 0.34149029 0.20074367 1.000 0.881 ! response to cAMP GO:0051591 60 60 3.000 0.05001093 0.34046479 0.05001093 1.000 0.871 ! positive regulation of cell division GO:0051781 61 60 3.000 0.05001093 0.33944543 0.20074367 1.000 0.840 ! regulation of nucleotide biosynthetic process GO:0030808 145 145 5.000 0.05075572 0.34347226 0.59722637 1.000 0.946 ! cellular response to oxidative stress GO:0034599 101 101 4.000 0.05126697 0.34589945 0.16354857 1.000 0.946 ! renal system development GO:0072001 193 193 6.000 0.05159054 0.3470497 0.05159054 1.000 0.946 ! biomineral tissue development GO:0031214 61 61 3.000 0.05208108 0.34931308 0.57218947 1.000 0.743 ! response to vitamin A GO:0033189 102 102 4.000 0.05280628 0.35313227 0.16690439 1.000 0.946 ! multicellular organismal aging GO:0010259 27 27 2.000 0.05310261 0.35406947 0.05310261 1.000 0.803 ! forebrain neuron differentiation GO:0021879 27 27 2.000 0.05310261 0.35303114 0.31302682 1.000 0.819 ! neuron maturation GO:0042551 27 27 2.000 0.05310261 0.35199888 0.05310261 1.000 0.657 ! regulation of vascular permeability GO:0043114 27 27 2.000 0.05310261 0.35097265 1.000 1.000 0.813 ! ventricular septum morphogenesis GO:0060412 27 27 2.000 0.05310261 0.34995238 1.000 1.000 0.848 ! regulation of cardiac muscle cell action potential GO:0086001 27 27 2.000 0.05310261 0.34893802 0.31302682 1.000 0.812 ! response to lipopolysaccharide GO:0032496 195 195 6.000 0.05372661 0.35201797 0.50624803 1.000 0.946 ! regulation of gliogenesis GO:0014013 63 62 3.000 0.05419214 0.3540449 0.21083611 1.000 0.884 ! receptor metabolic process GO:0043112 62 62 3.000 0.05419214 0.35302753 1.000 1.000 0.864 ! regulation of cellular carbohydrate metabolic process GO:0010675 104 103 4.000 0.05437059 0.35317512 0.17028041 1.000 0.946 ! digestive tract development GO:0048565 103 103 4.000 0.05437059 0.35216605 0.41693014 1.000 0.892 ! regulation of cyclic nucleotide metabolic process GO:0030799 149 149 5.000 0.05580366 0.36041848 0.61206274 1.000 0.946 ! hormone metabolic process GO:0042445 149 149 5.000 0.05580366 0.35939457 0.05580366 1.000 0.946 ! cholesterol metabolic process GO:0008203 104 104 4.000 0.05595982 0.35937935 0.05595982 1.000 0.946 ! BMP signaling pathway GO:0030509 63 63 3.000 0.05634372 0.36082265 0.05634372 1.000 0.842 ! regulation of epithelial cell differentiation GO:0030856 63 63 3.000 0.05634372 0.35980624 0.05634372 1.000 0.881 ! negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043154 64 63 3.000 0.05634372 0.35879555 1.000 1.000 0.857 ! myotube differentiation GO:0014902 28 28 2.000 0.05668035 0.35992816 0.32252113 1.000 0.782 ! negative regulation of cell-cell adhesion GO:0022408 28 28 2.000 0.05668035 0.35892277 1.000 1.000 0.833 ! regulation of phosphoprotein phosphatase activity GO:0043666 28 28 2.000 0.05668035 0.35792299 0.32252113 1.000 0.671 ! cardiac conduction GO:0061337 28 28 2.000 0.05668035 0.35692876 0.05668035 1.000 0.829 ! regulation of extrinsic apoptotic signaling pathway GO:2001236 28 28 2.000 0.05668035 0.35594004 0.05668035 1.000 0.726 ! positive regulation of homeostatic process GO:0032846 64 64 3.000 0.05853545 0.3665742 0.58971697 1.000 0.886 ! negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 64 64 3.000 0.05853545 0.36556436 0.58971697 1.000 0.699 ! inositol phosphate-mediated signaling GO:0048016 64 64 3.000 0.05853545 0.36456006 0.58971697 1.000 0.864 ! positive regulation of BMP signaling pathway GO:0030513 29 29 2.000 0.06033973 0.3747676 0.06033973 1.000 0.815 ! regulation of fatty acid biosynthetic process GO:0042304 29 29 2.000 0.06033973 0.37374365 0.33188476 1.000 0.833 ! positive regulation of fat cell differentiation GO:0045600 31 29 2.000 0.06033973 0.37272527 0.33188476 1.000 0.654 ! oocyte development GO:0048599 29 29 2.000 0.06033973 0.37171243 0.33188476 1.000 0.787 ! neural crest cell differentiation GO:0014033 65 65 3.000 0.06076692 0.37332958 0.22606381 1.000 0.885 ! positive regulation of protein import into nucleus GO:0042307 65 65 3.000 0.06076692 0.37232059 0.59539905 1.000 0.885 ! regulation of adenylate cyclase activity GO:0045761 107 107 4.000 0.06087636 0.37198574 0.77491943 1.000 0.946 ! amine biosynthetic process GO:0009309 154 154 5.000 0.06250693 0.38092258 0.16422961 1.000 0.946 ! regulation of carbohydrate metabolic process GO:0006109 109 108 4.000 0.06256455 0.38025154 0.18744444 1.000 0.946 ! activation of phospholipase C activity GO:0007202 108 108 4.000 0.06256455 0.37923483 0.77804414 1.000 0.946 ! calcium-mediated signaling GO:0019722 67 66 3.000 0.06303774 0.38108415 0.23115838 1.000 0.851 ! gastrulation with mouth forming second GO:0001702 31 30 2.000 0.06407785 0.38634169 0.06407785 1.000 0.802 ! regulation of cation channel activity GO:2001257 30 30 2.000 0.06407785 0.38531691 0.34111948 1.000 0.815 ! renal system process GO:0003014 67 67 3.000 0.06534748 0.39191199 1.000 1.000 0.889 ! negative regulation of cysteine-type endopeptidase activity GO:2000117 68 67 3.000 0.06534748 0.39087792 1.000 1.000 0.862 ! sterol metabolic process GO:0016125 110 110 4.000 0.06601437 0.39382782 0.06601437 1.000 0.946 ! positive regulation of cyclase activity GO:0031281 68 68 3.000 0.06769571 0.40279834 0.61197932 1.000 0.866 ! regulation of transporter activity GO:0032409 68 68 3.000 0.06769571 0.4017439 0.61197932 1.000 0.878 ! adult walking behavior GO:0007628 31 31 2.000 0.06789184 0.40185587 0.35022707 1.000 0.823 ! oocyte differentiation GO:0009994 31 31 2.000 0.06789184 0.40080937 0.35022707 1.000 0.795 ! regulation of gastrulation GO:0010470 32 31 2.000 0.06789184 0.39976831 0.35022707 1.000 0.866 ! response to tropane GO:0014073 31 31 2.000 0.06789184 0.39873264 1.000 1.000 0.858 GO:0042220|response to cocaine, ! response to cocaine GO:0042220 31 31 2.000 0.06789184 0.39873264 1.000 1.000 0.858 GO:0014073|response to tropane, ! tissue regeneration GO:0042246 31 31 2.000 0.06789184 0.39770232 0.35022707 1.000 0.709 ! regulation of multicellular organismal metabolic process GO:0044246 31 31 2.000 0.06789184 0.39667731 0.06789184 1.000 0.856 ! regulation of neurotransmitter secretion GO:0046928 31 31 2.000 0.06789184 0.39565758 1.000 1.000 0.765 ! negative regulation of lipid biosynthetic process GO:0051055 31 31 2.000 0.06789184 0.39464307 0.06789184 1.000 0.854 ! regulation of synapse assembly GO:0051963 31 31 2.000 0.06789184 0.39363375 0.35022707 1.000 0.813 ! digestive system development GO:0055123 112 112 4.000 0.06956142 0.40228506 0.45910905 1.000 0.946 ! negative regulation of inflammatory response GO:0050728 70 69 3.000 0.07008199 0.4042643 1.000 1.000 0.883 ! palate development GO:0060021 69 69 3.000 0.07008199 0.40323825 0.07008199 1.000 0.872 ! telencephalon development GO:0021537 161 160 5.000 0.07112528 0.40820509 0.18040106 1.000 0.946 ! superoxide metabolic process GO:0006801 32 32 2.000 0.07177893 0.41091622 0.07177893 1.000 0.802 ! apoptotic nuclear change GO:0030262 32 32 2.000 0.07177893 0.40988117 0.07177893 1.000 0.702 ! bone mineralization GO:0030282 32 32 2.000 0.07177893 0.40885132 1.000 1.000 0.693 ! midbrain development GO:0030901 32 32 2.000 0.07177893 0.40782663 0.35920926 1.000 0.714 ! regulation of circadian rhythm GO:0042752 32 32 2.000 0.07177893 0.40680706 0.35920926 1.000 0.770 ! cell differentiation involved in kidney development GO:0061005 32 32 2.000 0.07177893 0.40579258 0.07177893 1.000 0.872 ! cellular response to lipid GO:0071396 32 32 2.000 0.07177893 0.40478314 0.35920926 1.000 0.844 ! RNA export from nucleus GO:0006405 70 70 3.000 0.07250587 0.40786802 0.25159822 1.000 0.627 ! regulation of fatty acid metabolic process GO:0019217 70 70 3.000 0.07250587 0.40685844 0.6226551 1.000 0.877 ! positive regulation of endocytosis GO:0045807 70 70 3.000 0.07250587 0.40585385 1.000 1.000 0.882 ! positive regulation of lyase activity GO:0051349 70 70 3.000 0.07250587 0.40485421 0.6226551 1.000 0.868 ! positive regulation of phospholipase C activity GO:0010863 114 114 4.000 0.07320479 0.40775248 0.79590563 1.000 0.946 ! mRNA transport GO:0051028 114 114 4.000 0.07320479 0.40675309 0.208596 1.000 0.692 ! phagocytosis GO:0006909 71 71 3.000 0.0749669 0.41552556 0.25671797 1.000 0.812 ! glial cell development GO:0021782 73 71 3.000 0.0749669 0.41451209 0.62788278 1.000 0.878 ! pancreas development GO:0031016 71 71 3.000 0.0749669 0.41350354 0.25671797 1.000 0.873 ! membrane depolarization GO:0051899 71 71 3.000 0.0749669 0.41249989 0.62788278 1.000 0.881 ! glial cell differentiation GO:0010001 117 115 4.000 0.07506228 0.41202467 0.47277439 1.000 0.946 ! positive regulation of epithelial cell proliferation GO:0050679 115 115 4.000 0.07506228 0.41102944 0.47277439 1.000 0.946 ! smooth muscle cell differentiation GO:0051145 33 33 2.000 0.07573638 0.41372139 0.36806779 1.000 0.834 ! mitotic cell cycle spindle checkpoint GO:0071174 33 33 2.000 0.07573638 0.41272687 1.000 1.000 0.718 ! osteoblast differentiation GO:0001649 72 72 3.000 0.0774646 0.42113248 0.0774646 1.000 0.872 ! glycerol ether metabolic process GO:0006662 117 117 4.000 0.0788482 0.42762888 0.0788482 1.000 0.946 ! neural retina development GO:0003407 34 34 2.000 0.07976154 0.43154992 0.07976154 1.000 0.770 ! positive regulation of gliogenesis GO:0014015 35 34 2.000 0.07976154 0.43052242 0.37680434 1.000 0.852 ! mammary gland duct morphogenesis GO:0060603 34 34 2.000 0.07976154 0.4294998 0.37680434 1.000 0.861 ! positive regulation of neurogenesis GO:0050769 119 118 4.000 0.08077635 0.43393361 0.48623074 1.000 0.946 ! cellular component disassembly involved in apoptosis GO:0006921 74 74 3.000 0.08256812 0.44251045 0.27208382 1.000 0.823 ! negative regulation of binding GO:0051100 74 74 3.000 0.08256812 0.44146679 0.64313694 1.000 0.880 ! cellular response to extracellular stimulus GO:0031668 169 168 5.000 0.08357948 0.4458228 0.08357948 1.000 0.946 ! embryonic axis specification GO:0000578 35 35 2.000 0.0838518 0.44622545 0.0838518 1.000 0.826 ! activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway GO:0007205 35 35 2.000 0.0838518 0.44518042 0.38542059 1.000 0.655 ! negative regulation of protein binding GO:0032091 35 35 2.000 0.0838518 0.44414028 0.38542059 1.000 0.835 ! regulation of chondrocyte differentiation GO:0032330 35 35 2.000 0.0838518 0.44310499 0.0838518 1.000 0.797 ! negative regulation of blood pressure GO:0045776 35 35 2.000 0.0838518 0.44207451 0.38542059 1.000 0.866 ! embryonic digestive tract development GO:0048566 35 35 2.000 0.0838518 0.44104882 0.38542059 1.000 0.866 ! cardiac muscle cell development GO:0055013 35 35 2.000 0.0838518 0.44002787 1.000 1.000 0.853 ! multicellular organismal homeostasis GO:0048871 120 120 4.000 0.08470228 0.44346435 0.23024723 1.000 0.946 ! positive regulation of transmembrane transport GO:0034764 75 75 3.000 0.08517296 0.44490115 0.64808198 1.000 0.888 ! divalent metal ion transport GO:0070838 170 170 5.000 0.08686241 0.45268295 0.20845091 1.000 0.946 ! spindle checkpoint GO:0031577 36 36 2.000 0.08800462 0.45758366 1.000 1.000 0.730 ! skeletal muscle cell differentiation GO:0035914 37 36 2.000 0.08800462 0.45653656 0.39391819 1.000 0.800 ! regulation of NF-kappaB import into nucleus GO:0042345 36 36 2.000 0.08800462 0.45549424 0.39391819 1.000 0.843 ! gastrulation GO:0007369 124 122 4.000 0.08872 0.45815088 0.23755666 1.000 0.946 ! organic ether metabolic process GO:0018904 122 122 4.000 0.08872 0.45710963 0.08872 1.000 0.946 ! negative regulation of cell migration GO:0030336 123 122 4.000 0.08872 0.4560731 0.81751341 1.000 0.946 ! negative regulation of response to external stimulus GO:0032102 123 122 4.000 0.08872 0.45504126 1.000 1.000 0.946 ! regulation of microtubule cytoskeleton organization GO:0070507 79 77 3.000 0.09048634 0.4630531 0.65776823 1.000 0.851 ! regulation of epidermis development GO:0045682 37 37 2.000 0.0922175 0.47084929 0.0922175 1.000 0.809 ! epidermis morphogenesis GO:0048730 37 37 2.000 0.0922175 0.4697912 1.000 1.000 0.821 ! cardiac cell development GO:0055006 37 37 2.000 0.0922175 0.46873785 1.000 1.000 0.861 ! lung morphogenesis GO:0060425 37 37 2.000 0.0922175 0.46768922 0.40229877 1.000 0.866 ! GTP catabolic process GO:0006184 124 124 4.000 0.09282819 0.46973551 0.09282819 1.000 0.712 ! regulation of endocytosis GO:0030100 124 124 4.000 0.09282819 0.46868933 0.82254939 1.000 0.946 ! organelle localization GO:0051640 175 174 5.000 0.093628 0.47167704 0.69540505 1.000 0.946 ! divalent inorganic cation transport GO:0072511 174 174 5.000 0.093628 0.47063119 0.22000671 1.000 0.946 ! negative regulation of cell motility GO:2000146 126 125 4.000 0.09491578 0.47604884 0.82501523 1.000 0.946 ! positive regulation of nucleocytoplasmic transport GO:0046824 79 79 3.000 0.09593458 0.48009644 0.66718892 1.000 0.887 ! forebrain generation of neurons GO:0021872 38 38 2.000 0.09648802 0.48180253 0.41056392 1.000 0.862 ! muscle filament sliding GO:0030049 38 38 2.000 0.09648802 0.48074362 0.41056392 1.000 0.682 GO:0033275|actin-myosin filament sliding, ! actin-myosin filament sliding GO:0033275 38 38 2.000 0.09648802 0.48074362 0.41056392 1.000 0.682 GO:0030049|muscle filament sliding, ! hindlimb morphogenesis GO:0035137 38 38 2.000 0.09648802 0.47968936 0.09648802 1.000 0.819 ! retina morphogenesis in camera-type eye GO:0060042 38 38 2.000 0.09648802 0.47863971 0.09648802 1.000 0.805 ! anatomical structure maturation GO:0071695 38 38 2.000 0.09648802 0.47759464 0.41056392 1.000 0.840 ! protein localization to nucleus GO:0034504 127 127 4.000 0.09915706 0.48973648 0.25599572 1.000 0.946 ! cell fate determination GO:0001709 39 39 2.000 0.1008138 0.49683669 1.000 1.000 0.854 ! respiratory gaseous exchange GO:0007585 39 39 2.000 0.1008138 0.49575896 0.1008138 1.000 0.659 ! negative regulation of mitosis GO:0045839 39 39 2.000 0.1008138 0.49468589 1.000 1.000 0.782 GO:0051784|negative regulation of nuclear division, ! negative regulation of nuclear division GO:0051784 39 39 2.000 0.1008138 0.49468589 1.000 1.000 0.782 GO:0045839|negative regulation of mitosis, ! metanephros development GO:0001656 81 81 3.000 0.10151356 0.49704371 0.10151356 1.000 0.891 ! cellular response to hypoxia GO:0071456 81 81 3.000 0.10151356 0.4959725 0.67635131 1.000 0.882 ! protein localization in membrane GO:0072657 82 81 3.000 0.10151356 0.49490589 0.10151356 1.000 0.873 ! protein dephosphorylation GO:0006470 129 129 4.000 0.10348521 0.50343554 0.10348521 1.000 0.680 ! neural crest cell migration GO:0001755 40 40 2.000 0.10519251 0.51064543 0.42675429 1.000 0.845 ! receptor internalization GO:0031623 40 40 2.000 0.10519251 0.5095543 1.000 1.000 0.836 ! regulation of cell adhesion mediated by integrin GO:0033628 41 40 2.000 0.10519251 0.50846783 0.42675429 1.000 0.865 ! positive regulation of neuron apoptosis GO:0043525 40 40 2.000 0.10519251 0.50738599 0.10519251 1.000 0.843 ! regulation of blood vessel endothelial cell migration GO:0043535 40 40 2.000 0.10519251 0.50630874 1.000 1.000 0.860 ! regulation of cAMP biosynthetic process GO:0030817 130 130 4.000 0.10568138 0.50758407 0.83684182 1.000 0.946 ! regulation of protein import into nucleus GO:0042306 130 130 4.000 0.10568138 0.50651096 0.5378628 1.000 0.946 ! nucleic acid transport GO:0050657 130 130 4.000 0.10568138 0.50544237 0.26715406 1.000 0.754 GO:0051236|establishment of RNA localization, GO:0050658|RNA transport, ! RNA transport GO:0050658 130 130 4.000 0.10568138 0.50544237 0.26715406 1.000 0.754 GO:0051236|establishment of RNA localization, GO:0050657|nucleic acid transport, ! establishment of RNA localization GO:0051236 130 130 4.000 0.10568138 0.50544237 0.26715406 1.000 0.754 GO:0050658|RNA transport, GO:0050657|nucleic acid transport, ! female gonad development GO:0008585 83 83 3.000 0.10721908 0.51171715 0.10721908 1.000 0.876 ! regulation of glucose metabolic process GO:0010906 83 83 3.000 0.10721908 0.51064211 0.10721908 1.000 0.883 ! gliogenesis GO:0042063 133 131 4.000 0.10789868 0.51280151 0.54200197 1.000 0.946 ! negative regulation of cellular component movement GO:0051271 132 131 4.000 0.10789868 0.5117287 0.83910982 1.000 0.946 ! transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178 182 182 5.000 0.1079408 0.51085971 0.1079408 1.000 0.946 ! regulation of microtubule polymerization or depolymerization GO:0031110 42 41 2.000 0.10962188 0.51773501 1.000 1.000 0.765 ! regulation of interleukin-12 production GO:0032655 41 41 2.000 0.10962188 0.51665864 0.4346826 1.000 0.858 ! endothelial cell differentiation GO:0045446 41 41 2.000 0.10962188 0.51558674 1.000 1.000 0.838 ! positive regulation of lipid biosynthetic process GO:0046889 41 41 2.000 0.10962188 0.51451927 0.4346826 1.000 0.876 ! negative regulation of axonogenesis GO:0050771 41 41 2.000 0.10962188 0.51345621 0.4346826 1.000 0.813 ! positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 183 183 5.000 0.1098015 0.5132371 0.24659301 1.000 0.946 ! negative regulation of defense response GO:0031348 85 84 3.000 0.11011796 0.51365721 1.000 1.000 0.887 ! regulation of cAMP metabolic process GO:0030814 132 132 4.000 0.11013693 0.51269078 0.84134641 1.000 0.946 ! appendage morphogenesis GO:0035107 133 133 4.000 0.11239589 0.5221342 0.27836872 1.000 0.946 GO:0035108|limb morphogenesis, ! limb morphogenesis GO:0035108 133 133 4.000 0.11239589 0.5221342 0.27836872 1.000 0.946 GO:0035107|appendage morphogenesis, ! cellular response to organic cyclic compound GO:0071407 42 42 2.000 0.1140997 0.52896529 1.000 1.000 0.873 ! segmentation GO:0035282 86 86 3.000 0.11600527 0.53670194 0.11600527 1.000 0.882 ! pituitary gland development GO:0021983 43 43 2.000 0.11862381 0.54769891 1.000 1.000 0.867 ! negative regulation of protein catabolic process GO:0042177 43 43 2.000 0.11862381 0.54658571 0.11862381 1.000 0.807 ! regulation of steroid biosynthetic process GO:0050810 43 43 2.000 0.11862381 0.54547701 0.11862381 1.000 0.867 ! endochondral bone morphogenesis GO:0060350 43 43 2.000 0.11862381 0.54437281 0.11862381 1.000 0.832 ! positive regulation of chromosome organization GO:2001252 43 43 2.000 0.11862381 0.54327306 1.000 1.000 0.872 ! RNA localization GO:0006403 137 137 4.000 0.12163483 0.55593983 0.29338904 1.000 0.777 ! GTP metabolic process GO:0046039 137 137 4.000 0.12163483 0.55482124 0.12163483 1.000 0.772 ! axis specification GO:0009798 88 88 3.000 0.12200838 0.55540764 0.34327316 1.000 0.888 ! cellular response to oxygen levels GO:0071453 88 88 3.000 0.12200838 0.5542946 0.70648566 1.000 0.886 ! positive regulation of phosphatidylinositol 3-kinase cascade GO:0014068 44 44 2.000 0.12319207 0.55855285 0.45781821 1.000 0.869 ! nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway GO:0035872 44 44 2.000 0.12319207 0.55743798 0.12319207 1.000 0.839 ! cellular response to fibroblast growth factor stimulus GO:0044344 138 138 4.000 0.12399425 0.55995012 0.57025315 1.000 0.946 ! response to glucose stimulus GO:0009749 89 89 3.000 0.125052 0.56360414 0.34828974 1.000 0.887 ! dorsal/ventral pattern formation GO:0009953 89 89 3.000 0.125052 0.56248588 0.125052 1.000 0.946 ! positive regulation of cell growth GO:0030307 90 89 3.000 0.125052 0.56137205 0.34828974 1.000 0.879 ! generation of a signal involved in cell-cell signaling GO:0003001 140 139 4.000 0.1263731 0.56618147 0.1263731 1.000 0.946 GO:0023061|signal release, ! signal release GO:0023061 140 139 4.000 0.1263731 0.56618147 0.1263731 1.000 0.946 GO:0003001|generation of a signal involved in cell-cell signaling, ! response to fibroblast growth factor stimulus GO:0071774 139 139 4.000 0.1263731 0.56506474 0.57418502 1.000 0.946 ! positive regulation of cellular carbohydrate metabolic process GO:0010676 46 45 2.000 0.12780243 0.57033094 0.46531857 1.000 0.866 ! regulation of skeletal muscle fiber development GO:0048742 46 45 2.000 0.12780243 0.56921045 0.12780243 1.000 0.850 ! actin-mediated cell contraction GO:0070252 45 45 2.000 0.12780243 0.56809435 0.46531857 1.000 0.734 ! regulation of protein kinase B signaling cascade GO:0051896 90 90 3.000 0.12812293 0.56840446 1.000 1.000 0.888 ! regulation of inflammatory response GO:0050727 194 193 5.000 0.12924889 0.57227975 1.000 1.000 0.946 ! protein import into nucleus GO:0006606 91 91 3.000 0.13122062 0.57987748 0.35828393 1.000 0.946 ! regulation of smooth muscle contraction GO:0006940 46 46 2.000 0.13245288 0.58418418 1.000 1.000 0.860 ! multicellular organismal metabolic process GO:0044236 46 46 2.000 0.13245288 0.58304984 0.13245288 1.000 0.690 ! icosanoid biosynthetic process GO:0046456 46 46 2.000 0.13245288 0.5819199 0.47271558 1.000 0.789 ! regulation of microtubule-based process GO:0032886 94 92 3.000 0.13434453 0.58908906 0.72243304 1.000 0.946 ! negative regulation of neurogenesis GO:0050768 92 92 3.000 0.13434453 0.58795182 0.36326036 1.000 0.885 ! appendage development GO:0048736 143 143 4.000 0.13607831 0.59439217 0.31601034 1.000 0.946 GO:0060173|limb development, ! limb development GO:0060173 143 143 4.000 0.13607831 0.59439217 0.31601034 1.000 0.946 GO:0048736|appendage development, ! glycogen metabolic process GO:0005977 47 47 2.000 0.13714142 0.59788385 0.13714142 1.000 0.775 ! aerobic respiration GO:0009060 48 47 2.000 0.13714142 0.59673628 0.13714142 1.000 0.803 ! proteoglycan biosynthetic process GO:0030166 47 47 2.000 0.13714142 0.59559311 0.13714142 1.000 0.770 ! mammary gland morphogenesis GO:0060443 47 47 2.000 0.13714142 0.59445431 0.48001068 1.000 0.873 ! regulation of epithelial cell proliferation GO:0050678 197 197 5.000 0.13744018 0.59461238 0.51307926 1.000 0.946 ! regulation of phosphatase activity GO:0010921 93 93 3.000 0.1374941 0.5937126 0.36822226 1.000 0.640 ! positive regulation of lipid metabolic process GO:0045834 93 93 3.000 0.1374941 0.59258387 0.72628316 1.000 0.892 ! dephosphorylation GO:0016311 145 145 4.000 0.14104155 0.60671954 0.14104155 1.000 0.751 ! cartilage development GO:0051216 145 145 4.000 0.14104155 0.60557045 0.14104155 1.000 0.946 ! endothelium development GO:0003158 48 48 2.000 0.14186615 0.60795947 1.000 1.000 0.851 ! endocrine pancreas development GO:0031018 48 48 2.000 0.14186615 0.60681238 0.14186615 1.000 0.838 ! positive regulation of carbohydrate metabolic process GO:0045913 49 48 2.000 0.14186615 0.60566961 0.48720524 1.000 0.872 ! acylglycerol metabolic process GO:0006639 95 95 3.000 0.14386802 0.61306168 0.14386802 1.000 0.946 ! inner ear morphogenesis GO:0042472 95 95 3.000 0.14386802 0.61191147 0.37810028 1.000 0.946 ! lung development GO:0030324 147 147 4.000 0.14607603 0.62013924 0.33111516 1.000 0.946 ! positive regulation of growth GO:0045927 148 147 4.000 0.14607603 0.61898011 0.60469701 1.000 0.946 ! cellular glucan metabolic process GO:0006073 49 49 2.000 0.14662518 0.62014791 0.14662518 1.000 0.788 GO:0044042|glucan metabolic process, ! glucan metabolic process GO:0044042 49 49 2.000 0.14662518 0.62014791 0.14662518 1.000 0.788 GO:0006073|cellular glucan metabolic process, ! regulation of mRNA processing GO:0050684 49 49 2.000 0.14662518 0.61899307 0.49430066 1.000 0.652 ! protein homotetramerization GO:0051289 49 49 2.000 0.14662518 0.61784253 0.14662518 1.000 0.828 ! regulation of axonogenesis GO:0050770 96 96 3.000 0.14709128 0.61865666 0.38301536 1.000 0.946 ! regulation of insulin secretion GO:0050796 148 148 4.000 0.14861938 0.62392617 0.60839298 1.000 0.946 ! cellular hormone metabolic process GO:0034754 97 97 3.000 0.15033801 0.6299746 0.15033801 1.000 0.946 ! negative regulation of protein kinase activity GO:0006469 149 149 4.000 0.15117981 0.63233327 0.33866582 1.000 0.946 ! excretion GO:0007588 50 50 2.000 0.15141667 0.63215763 0.50129829 1.000 0.755 ! peptidyl-tyrosine dephosphorylation GO:0035335 50 50 2.000 0.15141667 0.63099558 0.15141667 1.000 0.404 ! regulation of synapse organization GO:0050807 50 50 2.000 0.15141667 0.62983779 0.50129829 1.000 0.848 ! positive regulation of intracellular protein transport GO:0090316 101 98 3.000 0.15360764 0.63778118 0.74475036 1.000 0.890 ! respiratory tube development GO:0030323 150 150 4.000 0.15375708 0.63723457 0.34243947 1.000 0.946 ! unsaturated fatty acid biosynthetic process GO:0006636 51 51 2.000 0.15623884 0.64633841 0.50819948 1.000 0.782 ! nucleobase-containing compound transport GO:0015931 151 151 4.000 0.15635095 0.64562405 0.34621153 1.000 0.946 ! regulation of chromosome organization GO:0033044 99 99 3.000 0.15689965 0.64671181 1.000 1.000 0.889 ! long-chain fatty acid metabolic process GO:0001676 52 52 2.000 0.16108993 0.66277837 0.51500555 1.000 0.839 ! regulation of translational initiation GO:0006446 53 52 2.000 0.16108993 0.66157768 0.51500555 1.000 0.638 ! regulation of ion transmembrane transporter activity GO:0032412 52 52 2.000 0.16108993 0.66038134 0.51500555 1.000 0.867 ! ethanolamine-containing compound metabolic process GO:0042439 52 52 2.000 0.16108993 0.65918931 0.16108993 1.000 0.805 ! positive regulation of peptide hormone secretion GO:0090277 52 52 2.000 0.16108993 0.65800158 1.000 1.000 0.865 ! positive regulation of peptide secretion GO:0002793 53 53 2.000 0.16596825 0.67670866 1.000 1.000 0.867 ! negative regulation of neuron differentiation GO:0045665 53 53 2.000 0.16596825 0.67549374 0.5217178 1.000 0.835 ! negative regulation of nucleocytoplasmic transport GO:0046823 53 53 2.000 0.16596825 0.67428318 0.5217178 1.000 0.845 ! regulation of kidney development GO:0090183 53 53 2.000 0.16596825 0.67307695 0.16596825 1.000 0.885 ! response to UV GO:0009411 103 102 3.000 0.16690439 0.67566475 0.41214082 1.000 0.946 ! mesenchymal cell development GO:0014031 102 102 3.000 0.16690439 0.67446035 0.75862636 1.000 0.891 ! vesicle organization GO:0016050 103 102 3.000 0.16690439 0.67326025 0.16690439 1.000 0.946 ! retina development in camera-type eye GO:0060041 103 103 3.000 0.17028041 0.68565841 0.17028041 1.000 0.946 ! regulation of acute inflammatory response GO:0002673 54 54 2.000 0.17087211 0.68682106 1.000 1.000 0.866 ! regulation of synapse structure and activity GO:0050803 54 54 2.000 0.17087211 0.68560545 0.52833753 1.000 0.857 ! nucleic acid phosphodiester bond hydrolysis GO:0090305 55 54 2.000 0.17087211 0.68439413 0.17087211 1.000 0.818 ! regulation of peptide hormone secretion GO:0090276 157 157 4.000 0.1722486 0.68869059 0.64047993 1.000 0.946 ! pattern recognition receptor signaling pathway GO:0002221 104 104 3.000 0.17367607 0.69317543 0.17367607 1.000 0.946 ! G-protein signaling, coupled to cAMP nucleotide second messenger GO:0007188 104 104 3.000 0.17367607 0.6919572 0.76527997 1.000 0.946 ! fat-soluble vitamin metabolic process GO:0006775 55 55 2.000 0.17579991 0.69919015 0.17579991 1.000 0.823 ! actin filament-based movement GO:0030048 55 55 2.000 0.17579991 0.69796565 0.53486601 1.000 0.770 ! negative regulation of lipid metabolic process GO:0045833 55 55 2.000 0.17579991 0.69674543 0.17579991 1.000 0.884 ! regulation of peptide secretion GO:0002791 159 159 4.000 0.17766917 0.70292496 0.64732423 1.000 0.946 GO:0090087|regulation of peptide transport, ! regulation of nucleocytoplasmic transport GO:0046822 159 159 4.000 0.17766917 0.70170035 0.64732423 1.000 0.946 ! regulation of peptide transport GO:0090087 159 159 4.000 0.17766917 0.70292496 0.64732423 1.000 0.946 GO:0002791|regulation of peptide secretion, ! negative regulation of kinase activity GO:0033673 160 160 4.000 0.18040106 0.7112508 0.38003446 1.000 0.946 ! positive regulation of intracellular transport GO:0032388 109 106 3.000 0.18052418 0.71050054 0.7717509 1.000 0.946 ! positive regulation of NF-kappaB transcription factor activity GO:0051092 106 106 3.000 0.18052418 0.70926917 0.43117885 1.000 0.946 ! protein secretion GO:0009306 56 56 2.000 0.18075004 0.70892794 0.18075004 1.000 0.786 ! regulation of cell-substrate adhesion GO:0010810 107 107 3.000 0.18397556 0.72033263 0.43588748 1.000 0.946 ! neural crest cell development GO:0014032 57 57 2.000 0.18572098 0.72591286 0.54765419 1.000 0.879 ! regulation of transmembrane transporter activity GO:0022898 57 57 2.000 0.18572098 0.72466344 0.54765419 1.000 0.875 ! negative regulation of transmembrane transport GO:0034763 57 57 2.000 0.18572098 0.72341832 0.18572098 1.000 0.859 ! protein import GO:0017038 163 162 4.000 0.18590678 0.72289996 0.38750615 1.000 0.946 ! innate immune response-activating signal transduction GO:0002758 108 108 3.000 0.18744444 0.72763109 0.18744444 1.000 0.946 ! inner ear development GO:0048839 163 163 4.000 0.1886801 0.73117569 0.66070368 1.000 0.946 ! nitrogen compound transport GO:0071705 163 163 4.000 0.1886801 0.72992795 0.39123414 1.000 0.946 ! positive regulation of cell-substrate adhesion GO:0010811 58 58 2.000 0.1907112 0.73652861 0.1907112 1.000 0.803 ! purine nucleotide biosynthetic process GO:0006164 110 109 3.000 0.19093031 0.73612076 0.44524134 1.000 0.946 ! negative regulation of organelle organization GO:0010639 164 164 4.000 0.1914667 0.7369355 1.000 1.000 0.946 ! fatty acid biosynthetic process GO:0006633 110 110 3.000 0.19443262 0.74708264 0.44988595 1.000 0.946 ! glutamine family amino acid metabolic process GO:0009064 59 59 2.000 0.19571924 0.75075385 0.19571924 1.000 0.864 ! somitogenesis GO:0001756 60 60 2.000 0.20074367 0.76872618 0.20074367 1.000 0.856 ! lens development in camera-type eye GO:0002088 60 60 2.000 0.20074367 0.76742984 0.56618281 1.000 0.805 ! cellular defense response GO:0006968 60 60 2.000 0.20074367 0.76613787 0.56618281 1.000 0.388 ! nucleoside monophosphate biosynthetic process GO:0009124 60 60 2.000 0.20074367 0.76485025 0.56618281 1.000 0.877 ! regulation of bone mineralization GO:0030500 60 60 2.000 0.20074367 0.76356694 0.20074367 1.000 0.862 ! mammary gland epithelium development GO:0061180 60 60 2.000 0.20074367 0.76228794 0.56618281 1.000 0.885 ! hindbrain development GO:0030902 113 112 3.000 0.20148452 0.76382177 0.20148452 1.000 0.946 ! respiratory system development GO:0060541 168 168 4.000 0.20274084 0.7673013 0.40978443 1.000 0.946 ! regulation of dephosphorylation GO:0035303 114 113 3.000 0.20503307 0.77468329 0.46368699 1.000 0.747 ! regulation of skeletal muscle tissue development GO:0048641 62 61 2.000 0.20578308 0.77622336 0.20578308 1.000 0.875 ! regulation of defense response to virus GO:0050688 62 61 2.000 0.20578308 0.77493395 0.20578308 1.000 0.842 ! positive regulation of MAPK cascade GO:0043410 171 170 4.000 0.20845091 0.78367864 0.90685334 1.000 0.946 ! cell fate specification GO:0001708 63 62 2.000 0.21083611 0.79133354 0.5781133 1.000 0.871 ! activation of adenylate cyclase activity GO:0007190 62 62 2.000 0.21083611 0.79002556 1.000 1.000 0.858 ! regulation of histone modification GO:0031056 62 62 2.000 0.21083611 0.78872188 1.000 1.000 0.877 ! regulation of RNA splicing GO:0043484 62 62 2.000 0.21083611 0.78742251 0.21083611 1.000 0.393 ! regulation of fibroblast proliferation GO:0048145 62 62 2.000 0.21083611 0.7861274 0.21083611 1.000 0.873 ! regulation of intracellular protein transport GO:0033157 174 171 4.000 0.2113233 0.7866501 0.68624146 1.000 0.946 ! negative regulation of transferase activity GO:0051348 171 171 4.000 0.2113233 0.78536051 0.42083337 1.000 0.946 ! negative regulation of Wnt receptor signaling pathway GO:0030178 118 115 3.000 0.21217279 0.78722704 0.47277439 1.000 0.946 ! ear morphogenesis GO:0042471 115 115 3.000 0.21217279 0.78594073 0.47277439 1.000 0.946 ! sulfur compound biosynthetic process GO:0044272 115 115 3.000 0.21217279 0.7846586 0.21217279 1.000 0.946 ! activation of innate immune response GO:0002218 116 116 3.000 0.21576295 0.79663618 0.21576295 1.000 0.946 ! establishment of organelle localization GO:0051656 117 116 3.000 0.21576295 0.79534084 0.8015354 1.000 0.946 ! mRNA export from nucleus GO:0006406 63 63 2.000 0.21590143 0.79455934 0.58395542 1.000 0.603 ! negative regulation of translation GO:0017148 67 63 2.000 0.21590143 0.79327156 0.58395542 1.000 0.795 ! response to amino acid stimulus GO:0043200 66 63 2.000 0.21590143 0.79198795 0.21590143 1.000 0.851 ! synaptic vesicle transport GO:0048489 63 63 2.000 0.21590143 0.79070848 1.000 1.000 0.812 ! dendrite development GO:0016358 64 64 2.000 0.22097776 0.80799447 0.22097776 1.000 0.830 ! regulation of steroid metabolic process GO:0019218 64 64 2.000 0.22097776 0.80669335 0.22097776 1.000 0.885 ! negative regulation of MAP kinase activity GO:0043407 64 64 2.000 0.22097776 0.80539642 0.22097776 1.000 0.839 ! positive regulation of protein transport GO:0051222 178 175 4.000 0.22292241 0.81117994 0.91316432 1.000 0.946 ! negative regulation of cell development GO:0010721 118 118 3.000 0.22298135 0.81009412 0.48623074 1.000 0.946 ! cAMP-mediated signaling GO:0019933 118 118 3.000 0.22298135 0.80879797 0.80701048 1.000 0.946 ! positive regulation of leukocyte migration GO:0002687 65 65 2.000 0.22606381 0.8186688 0.59539905 1.000 0.886 ! negative regulation of intracellular transport GO:0032387 65 65 2.000 0.22606381 0.81736311 0.59539905 1.000 0.868 ! positive regulation of adenylate cyclase activity GO:0045762 65 65 2.000 0.22606381 0.81606157 1.000 1.000 0.861 ! regulation of binding GO:0051098 177 177 4.000 0.2287841 0.82456845 0.70434718 1.000 0.946 ! mammary gland development GO:0030879 120 120 3.000 0.23024723 0.82852454 0.49508265 1.000 0.946 ! icosanoid metabolic process GO:0006690 66 66 2.000 0.23115838 0.83048502 0.60100276 1.000 0.847 ! integrin-mediated signaling pathway GO:0007229 66 66 2.000 0.23115838 0.82917096 0.60100276 1.000 0.681 ! regulation of BMP signaling pathway GO:0030510 66 66 2.000 0.23115838 0.82786105 0.23115838 1.000 0.863 ! negative regulation of protein complex assembly GO:0031333 66 66 2.000 0.23115838 0.82655528 1.000 1.000 0.844 ! cellular polysaccharide metabolic process GO:0044264 66 66 2.000 0.23115838 0.82525361 0.23115838 1.000 0.825 ! regulation of biomineral tissue development GO:0070167 66 66 2.000 0.23115838 0.82395605 0.23115838 1.000 0.869 ! morphogenesis of a branching structure GO:0001763 179 179 4.000 0.23468446 0.83521142 0.71018691 1.000 0.946 ! regulation of peptidyl-serine phosphorylation GO:0033135 68 67 2.000 0.23626025 0.83950156 1.000 1.000 0.876 ! regulation of transcription factor import into nucleus GO:0042990 67 67 2.000 0.23626025 0.83818778 0.60652916 1.000 0.879 ! regulation of DNA binding GO:0051101 67 67 2.000 0.23626025 0.83687811 1.000 1.000 0.880 ! fibroblast growth factor receptor signaling pathway GO:0008543 122 122 3.000 0.23755666 0.84015747 0.50383759 1.000 0.946 ! transforming growth factor beta receptor signaling pathway GO:0007179 123 123 3.000 0.2412265 0.8518076 0.2412265 1.000 0.946 ! purine-containing compound biosynthetic process GO:0072522 124 123 3.000 0.2412265 0.85048286 0.50817827 1.000 0.946 ! regulation of systemic arterial blood pressure GO:0003073 68 68 2.000 0.24136827 0.84966128 1.000 1.000 0.888 ! monocarboxylic acid transport GO:0015718 70 68 2.000 0.24136827 0.84834398 0.61197932 1.000 0.838 ! regulation of type I interferon production GO:0032479 68 68 2.000 0.24136827 0.84703075 0.24136827 1.000 0.842 ! regulation of striated muscle cell differentiation GO:0051153 69 68 2.000 0.24136827 0.84572159 0.24136827 1.000 0.879 ! somite development GO:0061053 68 68 2.000 0.24136827 0.84441646 0.24136827 1.000 0.871 ! regulation of alternative nuclear mRNA splicing, via spliceosome GO:0000381 20 20 1.000 0.24275143 0.84794684 0.24275143 1.000 0.186 ! columnar/cuboidal epithelial cell differentiation GO:0002065 20 20 1.000 0.24275143 0.84664231 1.000 1.000 0.756 ! protein demethylation GO:0006482 20 20 1.000 0.24275143 0.84534178 0.24275143 1.000 0.630 GO:0008214|protein dealkylation, ! estrogen metabolic process GO:0008210 20 20 1.000 0.24275143 0.84404525 0.24275143 1.000 0.638 ! protein dealkylation GO:0008214 20 20 1.000 0.24275143 0.84534178 0.24275143 1.000 0.630 GO:0006482|protein demethylation, ! positive regulation of collagen metabolic process GO:0010714 20 20 1.000 0.24275143 0.84275268 0.24275143 1.000 0.814 GO:0032967|positive regulation of collagen biosynthetic process, ! regulation of myotube differentiation GO:0010830 20 20 1.000 0.24275143 0.84146407 0.24275143 1.000 0.707 ! forebrain regionalization GO:0021871 20 20 1.000 0.24275143 0.84017939 0.24275143 1.000 0.727 ! osteoclast differentiation GO:0030316 20 20 1.000 0.24275143 0.83889863 0.24275143 1.000 0.700 ! positive regulation of collagen biosynthetic process GO:0032967 20 20 1.000 0.24275143 0.84275268 0.24275143 1.000 0.814 GO:0010714|positive regulation of collagen metabolic process, ! response to testosterone stimulus GO:0033574 20 20 1.000 0.24275143 0.83762177 0.24275143 1.000 0.738 ! protein localization in Golgi apparatus GO:0034067 20 20 1.000 0.24275143 0.83634878 0.24275143 1.000 0.210 ! synaptic transmission, glutamatergic GO:0035249 20 20 1.000 0.24275143 0.83507967 1.000 1.000 0.675 ! macrophage activation GO:0042116 20 20 1.000 0.24275143 0.83381439 1.000 1.000 0.768 ! vasoconstriction GO:0042310 20 20 1.000 0.24275143 0.83255295 0.24275143 1.000 0.783 ! hydrogen peroxide catabolic process GO:0042744 20 20 1.000 0.24275143 0.83129532 0.24275143 1.000 0.639 ! peroxisomal transport GO:0043574 20 20 1.000 0.24275143 0.83004148 0.24275143 1.000 0.643 ! negative regulation of smoothened signaling pathway GO:0045879 20 20 1.000 0.24275143 0.82879142 0.24275143 1.000 0.613 ! response to copper ion GO:0046688 20 20 1.000 0.24275143 0.82754511 1.000 1.000 0.781 ! acid secretion GO:0046717 20 20 1.000 0.24275143 0.82630255 1.000 1.000 0.773 ! synaptic vesicle endocytosis GO:0048488 20 20 1.000 0.24275143 0.82506372 1.000 1.000 0.574 ! embryonic digestive tract morphogenesis GO:0048557 20 20 1.000 0.24275143 0.82382859 1.000 1.000 0.849 ! detection of mechanical stimulus involved in sensory perception GO:0050974 20 20 1.000 0.24275143 0.82259716 1.000 1.000 0.737 ! establishment of chromosome localization GO:0051303 21 20 1.000 0.24275143 0.8213694 1.000 1.000 0.698 ! negative regulation of oxidoreductase activity GO:0051354 20 20 1.000 0.24275143 0.82014531 1.000 1.000 0.791 ! cartilage development involved in endochondral bone morphogenesis GO:0060351 20 20 1.000 0.24275143 0.81892485 0.24275143 1.000 0.736 ! cellular response to alkaloid GO:0071312 20 20 1.000 0.24275143 0.81770802 1.000 1.000 0.845 ! otic vesicle development GO:0071599 20 20 1.000 0.24275143 0.81649481 1.000 1.000 0.778 ! lymphocyte migration GO:0072676 20 20 1.000 0.24275143 0.81528519 0.24275143 1.000 0.757 ! regulation of actin cytoskeleton organization GO:0032956 183 182 4.000 0.24360303 0.81693503 0.71876607 1.000 0.946 ! polysaccharide biosynthetic process GO:0000271 124 124 3.000 0.2449058 0.82009076 0.2449058 1.000 0.946 ! DNA catabolic process GO:0006308 69 69 2.000 0.24648129 0.8241491 0.24648129 1.000 0.844 ! oligosaccharide metabolic process GO:0009311 69 69 2.000 0.24648129 0.82293533 0.24648129 1.000 0.787 ! gonad development GO:0008406 184 184 4.000 0.24959113 0.83209278 0.46783422 1.000 0.946 ! cellular response to reactive oxygen species GO:0034614 70 70 2.000 0.25159822 0.83755236 0.25159822 1.000 0.871 ! regulation of ion transmembrane transport GO:0034765 70 70 2.000 0.25159822 0.83632428 0.6226551 1.000 0.883 ! positive regulation of inflammatory response GO:0050729 70 70 2.000 0.25159822 0.83509979 1.000 1.000 0.889 ! positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO:0090100 70 70 2.000 0.25159822 0.83387889 0.25159822 1.000 0.883 ! regulation of cell morphogenesis involved in differentiation GO:0010769 186 185 4.000 0.25259713 0.83596744 0.47138208 1.000 0.946 ! regulation of receptor internalization GO:0002090 21 21 1.000 0.25321289 0.83678371 1.000 1.000 0.766 ! regulation of membrane depolarization GO:0003254 21 21 1.000 0.25321289 0.83556568 0.25321289 1.000 0.780 ! aspartate family amino acid biosynthetic process GO:0009067 21 21 1.000 0.25321289 0.8343512 0.25321289 1.000 0.744 ! detection of visible light GO:0009584 21 21 1.000 0.25321289 0.83314024 0.25321289 1.000 0.634 ! monoamine transport GO:0015844 21 21 1.000 0.25321289 0.83193279 1.000 1.000 0.784 ! organic alcohol transport GO:0015850 21 21 1.000 0.25321289 0.83072883 1.000 1.000 0.760 ! reproductive behavior GO:0019098 21 21 1.000 0.25321289 0.82952836 0.25321289 1.000 0.770 ! positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 21 21 1.000 0.25321289 0.82833135 0.25321289 1.000 0.763 ! collagen catabolic process GO:0030574 21 21 1.000 0.25321289 0.82713779 0.25321289 1.000 0.0766 ! neuron projection regeneration GO:0031102 21 21 1.000 0.25321289 0.82594766 1.000 1.000 0.702 ! melanosome localization GO:0032400 21 21 1.000 0.25321289 0.82476095 0.25321289 1.000 0.734 ! response to ATP GO:0033198 21 21 1.000 0.25321289 0.82357765 1.000 1.000 0.748 ! aorta development GO:0035904 21 21 1.000 0.25321289 0.82239774 1.000 1.000 0.848 ! positive regulation of NF-kappaB import into nucleus GO:0042346 21 21 1.000 0.25321289 0.82122121 1.000 1.000 0.810 ! muscle adaptation GO:0043500 21 21 1.000 0.25321289 0.82004803 1.000 1.000 0.782 ! enteric nervous system development GO:0048484 21 21 1.000 0.25321289 0.81887821 0.25321289 1.000 0.736 ! chromosome localization GO:0050000 22 21 1.000 0.25321289 0.81771172 1.000 1.000 0.698 ! mitochondrion localization GO:0051646 21 21 1.000 0.25321289 0.81654854 0.25321289 1.000 0.624 ! negative regulation of ERK1 and ERK2 cascade GO:0070373 21 21 1.000 0.25321289 0.81538867 1.000 1.000 0.737 ! cellular response to glucocorticoid stimulus GO:0071385 21 21 1.000 0.25321289 0.81423209 1.000 1.000 0.771 ! regulation of stem cell differentiation GO:2000736 21 21 1.000 0.25321289 0.81307879 0.25321289 1.000 0.811 ! regulation of Wnt receptor signaling pathway GO:0030111 189 186 4.000 0.25561077 0.81961755 0.72987281 1.000 0.946 ! morphogenesis of embryonic epithelium GO:0016331 127 127 3.000 0.25599572 0.81969252 0.5252922 1.000 0.946 ! regulation of protein secretion GO:0050708 128 127 3.000 0.25599572 0.81853639 0.82984499 1.000 0.946 ! organic anion transport GO:0015711 72 72 2.000 0.26183949 0.83604243 0.26183949 1.000 0.751 ! limbic system development GO:0021761 73 72 2.000 0.26183949 0.83486656 0.63303832 1.000 0.875 ! regulation of cell-cell adhesion GO:0022407 73 72 2.000 0.26183949 0.83369399 1.000 1.000 0.884 ! regulation of canonical Wnt receptor signaling pathway GO:0060828 132 129 3.000 0.26342777 0.83757468 0.83454198 1.000 0.946 ! endothelial cell development GO:0001885 22 22 1.000 0.2635304 0.83672747 1.000 1.000 0.740 ! protein ADP-ribosylation GO:0006471 22 22 1.000 0.2635304 0.83555723 0.2635304 1.000 0.454 ! indolalkylamine metabolic process GO:0006586 22 22 1.000 0.2635304 0.83439025 0.2635304 1.000 0.767 GO:0042430|indole-containing compound metabolic process, ! bile acid biosynthetic process GO:0006699 22 22 1.000 0.2635304 0.83322652 0.2635304 1.000 0.642 ! endoplasmic reticulum organization GO:0007029 22 22 1.000 0.2635304 0.83206604 0.2635304 1.000 0.593 ! phosphatidylinositol 3-kinase cascade GO:0014065 22 22 1.000 0.2635304 0.83090878 0.2635304 1.000 0.692 ! calcium-independent cell-cell adhesion GO:0016338 22 22 1.000 0.2635304 0.82975474 0.2635304 1.000 0.00164 ! negative regulation of transporter activity GO:0032410 22 22 1.000 0.2635304 0.82860391 1.000 1.000 0.800 ! positive regulation of interferon-beta production GO:0032728 22 22 1.000 0.2635304 0.82745625 0.2635304 1.000 0.706 ! cholesterol efflux GO:0033344 22 22 1.000 0.2635304 0.82631178 0.2635304 1.000 0.774 ! indole-containing compound metabolic process GO:0042430 22 22 1.000 0.2635304 0.83439025 0.2635304 1.000 0.767 GO:0006586|indolalkylamine metabolic process, ! leukocyte degranulation GO:0043299 22 22 1.000 0.2635304 0.82517046 0.2635304 1.000 0.761 ! positive regulation of blood vessel endothelial cell migration GO:0043536 22 22 1.000 0.2635304 0.8240323 1.000 1.000 0.800 ! ceramide biosynthetic process GO:0046513 22 22 1.000 0.2635304 0.82289727 0.2635304 1.000 0.635 ! astrocyte differentiation GO:0048708 22 22 1.000 0.2635304 0.82176536 1.000 1.000 0.790 ! pigment granule localization GO:0051875 22 22 1.000 0.2635304 0.82063656 0.2635304 1.000 0.744 ! heart trabecula morphogenesis GO:0061384 22 22 1.000 0.2635304 0.81951086 1.000 1.000 0.817 ! lens fiber cell differentiation GO:0070306 22 22 1.000 0.2635304 0.81838824 1.000 1.000 0.634 ! cellular response to corticosteroid stimulus GO:0071384 22 22 1.000 0.2635304 0.81726869 1.000 1.000 0.784 ! cell communication involved in cardiac conduction GO:0086065 22 22 1.000 0.2635304 0.81615221 0.2635304 1.000 0.805 ! regulation of cellular amine metabolic process GO:0033238 73 73 2.000 0.26696177 0.82565121 0.63812271 1.000 0.858 ! ear development GO:0043583 190 190 4.000 0.26773664 0.82691957 0.74060668 1.000 0.946 ! hair follicle development GO:0001942 74 74 2.000 0.27208382 0.83920274 1.000 1.000 0.870 GO:0022405|hair cycle process, GO:0022404|molting cycle process, ! molting cycle process GO:0022404 74 74 2.000 0.27208382 0.83920274 1.000 1.000 0.870 GO:0022405|hair cycle process, GO:0001942|hair follicle development, ! hair cycle process GO:0022405 74 74 2.000 0.27208382 0.83920274 1.000 1.000 0.870 GO:0022404|molting cycle process, GO:0001942|hair follicle development, ! steroid catabolic process GO:0006706 23 23 1.000 0.27370593 0.8430589 0.27370593 1.000 0.682 ! regulation of epidermal growth factor-activated receptor activity GO:0007176 23 23 1.000 0.27370593 0.84191499 0.27370593 1.000 0.719 ! motor axon guidance GO:0008045 23 23 1.000 0.27370593 0.84077418 0.27370593 1.000 0.693 ! anterograde axon cargo transport GO:0008089 23 23 1.000 0.27370593 0.83963647 0.27370593 1.000 0.589 ! positive regulation of autophagy GO:0010508 23 23 1.000 0.27370593 0.83850182 0.27370593 1.000 0.590 ! positive regulation of epithelial to mesenchymal transition GO:0010718 23 23 1.000 0.27370593 0.83737024 0.27370593 1.000 0.816 ! protein sumoylation GO:0016925 23 23 1.000 0.27370593 0.83624171 0.27370593 1.000 0.572 ! heparan sulfate proteoglycan metabolic process GO:0030201 23 23 1.000 0.27370593 0.83511621 0.27370593 1.000 0.686 ! regulation of hormone metabolic process GO:0032350 23 23 1.000 0.27370593 0.83399375 0.27370593 1.000 0.825 ! positive regulation of ion transmembrane transporter activity GO:0032414 23 23 1.000 0.27370593 0.83287429 1.000 1.000 0.790 ! positive regulation of interleukin-1 beta production GO:0032731 23 23 1.000 0.27370593 0.83175784 1.000 1.000 0.819 ! regulation of collagen biosynthetic process GO:0032965 23 23 1.000 0.27370593 0.83064437 0.27370593 1.000 0.831 ! negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 23 23 1.000 0.27370593 0.82953389 1.000 1.000 0.739 ! middle ear morphogenesis GO:0042474 23 23 1.000 0.27370593 0.82842637 0.27370593 1.000 0.671 ! regulation of macrophage activation GO:0043030 23 23 1.000 0.27370593 0.8273218 1.000 1.000 0.789 ! receptor clustering GO:0043113 23 23 1.000 0.27370593 0.82622017 0.27370593 1.000 0.772 ! negative regulation of glial cell differentiation GO:0045686 23 23 1.000 0.27370593 0.82512147 0.27370593 1.000 0.800 ! regulation of astrocyte differentiation GO:0048710 23 23 1.000 0.27370593 0.82402569 0.27370593 1.000 0.817 ! regulation of oligodendrocyte differentiation GO:0048713 24 23 1.000 0.27370593 0.82293282 0.27370593 1.000 0.807 ! trabecula formation GO:0060343 23 23 1.000 0.27370593 0.82184284 1.000 1.000 0.812 ! chemokine-mediated signaling pathway GO:0070098 23 23 1.000 0.27370593 0.82075575 0.27370593 1.000 0.481 ! regulation of triglyceride metabolic process GO:0090207 23 23 1.000 0.27370593 0.81967153 0.27370593 1.000 0.780 ! epidermal growth factor receptor signaling pathway GO:0007173 133 132 3.000 0.27462497 0.8213388 0.27462497 1.000 0.946 ! negative regulation of protein modification process GO:0031400 193 193 4.000 0.27689902 0.82704884 0.93255686 1.000 0.946 ! ameboidal cell migration GO:0001667 75 75 2.000 0.27720466 0.82687233 0.64808198 1.000 0.878 ! myeloid leukocyte activation GO:0002274 75 75 2.000 0.27720466 0.82578577 0.64808198 1.000 0.880 ! single fertilization GO:0007338 76 75 2.000 0.27720466 0.82470206 0.27720466 1.000 0.600 ! regulation of multicellular organism growth GO:0040014 75 75 2.000 0.27720466 0.82362119 1.000 1.000 0.880 ! negative regulation of cytoskeleton organization GO:0051494 75 75 2.000 0.27720466 0.82254316 1.000 1.000 0.844 ! amine transport GO:0015837 134 134 3.000 0.28211742 0.8360264 0.5542651 1.000 0.946 ! negative regulation of cell projection organization GO:0031345 76 76 2.000 0.28232337 0.83554449 0.65295876 1.000 0.869 ! ribonucleoside triphosphate catabolic process GO:0009203 195 195 4.000 0.28303596 0.83656129 0.28303596 1.000 0.946 GO:0009207|purine ribonucleoside triphosphate catabolic process, ! purine ribonucleoside triphosphate catabolic process GO:0009207 195 195 4.000 0.28303596 0.83656129 0.28303596 1.000 0.946 GO:0009203|ribonucleoside triphosphate catabolic process, ! ciliary or flagellar motility GO:0001539 24 24 1.000 0.28374143 0.83755447 0.28374143 1.000 0.0920 ! lens morphogenesis in camera-type eye GO:0002089 24 24 1.000 0.28374143 0.83646532 0.28374143 1.000 0.719 ! glutamate metabolic process GO:0006536 24 24 1.000 0.28374143 0.835379 0.28374143 1.000 0.802 ! prostanoid metabolic process GO:0006692 24 24 1.000 0.28374143 0.8342955 1.000 1.000 0.733 GO:0006693|prostaglandin metabolic process, ! prostaglandin metabolic process GO:0006693 24 24 1.000 0.28374143 0.8342955 1.000 1.000 0.733 GO:0006692|prostanoid metabolic process, ! synapsis GO:0007129 24 24 1.000 0.28374143 0.83321481 0.28374143 1.000 0.652 ! response to lithium ion GO:0010226 24 24 1.000 0.28374143 0.83213691 1.000 1.000 0.782 ! regulation of muscle cell apoptosis GO:0010660 24 24 1.000 0.28374143 0.8310618 1.000 1.000 0.841 ! regulation of collagen metabolic process GO:0010712 24 24 1.000 0.28374143 0.82998946 0.28374143 1.000 0.836 ! stem cell division GO:0017145 24 24 1.000 0.28374143 0.82891989 1.000 1.000 0.809 ! adrenal gland development GO:0030325 24 24 1.000 0.28374143 0.82785306 0.28374143 1.000 0.811 ! regulation of epidermal cell differentiation GO:0045604 24 24 1.000 0.28374143 0.82678899 0.28374143 1.000 0.712 ! diacylglycerol metabolic process GO:0046339 24 24 1.000 0.28374143 0.82572764 0.28374143 1.000 0.619 ! regulation of protein export from nucleus GO:0046825 24 24 1.000 0.28374143 0.82466901 1.000 1.000 0.733 ! negative regulation of fibroblast proliferation GO:0048147 24 24 1.000 0.28374143 0.8236131 0.28374143 1.000 0.729 ! regulation of defense response to virus by host GO:0050691 25 24 1.000 0.28374143 0.82255989 0.28374143 1.000 0.804 ! molting cycle GO:0042303 77 77 2.000 0.28743902 0.8322149 1.000 1.000 0.867 GO:0042633|hair cycle, ! hair cycle GO:0042633 77 77 2.000 0.28743902 0.8322149 1.000 1.000 0.867 GO:0042303|molting cycle, ! purine nucleoside triphosphate catabolic process GO:0009146 197 197 4.000 0.2891936 0.83622689 0.2891936 1.000 0.946 ! sensory perception of mechanical stimulus GO:0050954 136 136 3.000 0.289628 0.83641614 0.56231116 1.000 0.946 ! sodium ion transport GO:0006814 78 78 2.000 0.29255074 0.84378184 0.29255074 1.000 0.628 ! regulation of behavior GO:0050795 137 137 3.000 0.29338904 0.84512446 0.56629519 1.000 0.946 ! negative regulation of endothelial cell proliferation GO:0001937 25 25 1.000 0.29363883 0.84477058 0.29363883 1.000 0.780 ! endocardial cushion development GO:0003197 25 25 1.000 0.29363883 0.84369989 1.000 1.000 0.841 ! axis elongation GO:0003401 25 25 1.000 0.29363883 0.84263192 1.000 1.000 0.837 ! phosphatidylcholine biosynthetic process GO:0006656 25 25 1.000 0.29363883 0.84156665 0.29363883 1.000 0.603 ! vesicle fusion GO:0006906 26 25 1.000 0.29363883 0.84050406 0.29363883 1.000 0.579 ! negative regulation of cellular carbohydrate metabolic process GO:0010677 25 25 1.000 0.29363883 0.83944416 0.29363883 1.000 0.817 ! Schwann cell differentiation GO:0014037 25 25 1.000 0.29363883 0.83838692 0.29363883 1.000 0.736 ! spinal cord motor neuron differentiation GO:0021522 25 25 1.000 0.29363883 0.83733235 1.000 1.000 0.703 ! cell proliferation in forebrain GO:0021846 25 25 1.000 0.29363883 0.83628042 1.000 1.000 0.751 ! positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 25 25 1.000 0.29363883 0.83523114 1.000 1.000 0.834 ! ephrin receptor signaling pathway GO:0048013 25 25 1.000 0.29363883 0.83418448 1.000 1.000 0.590 ! neuron fate specification GO:0048665 25 25 1.000 0.29363883 0.83314045 1.000 1.000 0.740 ! axon extension GO:0048675 25 25 1.000 0.29363883 0.83209902 0.29363883 1.000 0.724 ! regulation of chromosome segregation GO:0051983 26 25 1.000 0.29363883 0.8310602 1.000 1.000 0.775 ! intrinsic apoptotic signaling pathway GO:0097193 25 25 1.000 0.29363883 0.83002396 0.29363883 1.000 0.722 ! regulation of skeletal muscle cell differentiation GO:2001014 25 25 1.000 0.29363883 0.82899031 0.29363883 1.000 0.746 ! formation of primary germ layer GO:0001704 79 79 2.000 0.29765765 0.83929092 0.66718892 1.000 0.884 ! unsaturated fatty acid metabolic process GO:0033559 79 79 2.000 0.29765765 0.83824832 0.66718892 1.000 0.859 ! cilium assembly GO:0042384 79 79 2.000 0.29765765 0.83720831 0.29765765 1.000 0.643 ! DNA-dependent DNA replication GO:0006261 80 80 2.000 0.30275893 0.85050122 0.30275893 1.000 0.946 ! ovulation cycle process GO:0022602 80 80 2.000 0.30275893 0.84944862 0.30275893 1.000 0.883 ! protein tetramerization GO:0051262 80 80 2.000 0.30275893 0.84839862 0.30275893 1.000 0.870 ! nephron development GO:0072006 80 80 2.000 0.30275893 0.84735121 0.30275893 1.000 0.890 ! negative regulation of canonical Wnt receptor signaling pathway GO:0090090 83 80 2.000 0.30275893 0.84630639 0.67180196 1.000 0.868 ! endoderm formation GO:0001706 26 26 1.000 0.3034 0.84705394 0.3034 1.000 0.792 ! blastocyst formation GO:0001825 26 26 1.000 0.3034 0.84601205 0.3034 1.000 0.722 ! sister chromatid cohesion GO:0007062 26 26 1.000 0.3034 0.84497272 0.3034 1.000 0.662 ! glutamate receptor signaling pathway GO:0007215 26 26 1.000 0.3034 0.84393595 0.3034 1.000 0.746 ! regulation of cell fate commitment GO:0010453 26 26 1.000 0.3034 0.84290171 1.000 1.000 0.861 ! negative regulation of endothelial cell migration GO:0010596 26 26 1.000 0.3034 0.84187001 1.000 1.000 0.789 ! positive regulation of pathway-restricted SMAD protein phosphorylation GO:0010862 26 26 1.000 0.3034 0.84084083 0.3034 1.000 0.818 ! positive regulation of interleukin-1 production GO:0032732 26 26 1.000 0.3034 0.83981416 1.000 1.000 0.830 ! negative regulation of stress-activated MAPK cascade GO:0032873 26 26 1.000 0.3034 0.83879 0.3034 1.000 0.744 GO:0070303|negative regulation of stress-activated protein kinase signaling cascade, ! negative regulation of cytokine biosynthetic process GO:0042036 26 26 1.000 0.3034 0.83776833 1.000 1.000 0.783 ! vasodilation GO:0042311 26 26 1.000 0.3034 0.83674914 1.000 1.000 0.822 ! regulation of endocrine process GO:0044060 26 26 1.000 0.3034 0.83573244 1.000 1.000 0.841 ! positive regulation of multicellular organismal metabolic process GO:0044253 26 26 1.000 0.3034 0.8347182 0.3034 1.000 0.840 ! photoreceptor cell maintenance GO:0045494 26 26 1.000 0.3034 0.83370642 0.3034 1.000 0.581 ! negative regulation of carbohydrate metabolic process GO:0045912 26 26 1.000 0.3034 0.83269709 0.3034 1.000 0.824 ! nitric oxide metabolic process GO:0046209 26 26 1.000 0.3034 0.8316902 0.3034 1.000 0.735 ! positive regulation of Ras protein signal transduction GO:0046579 26 26 1.000 0.3034 0.83068574 1.000 1.000 0.763 ! negative regulation of insulin secretion GO:0046676 26 26 1.000 0.3034 0.82968371 1.000 1.000 0.778 ! sympathetic nervous system development GO:0048485 26 26 1.000 0.3034 0.82868409 1.000 1.000 0.822 ! negative regulation of smooth muscle cell proliferation GO:0048662 26 26 1.000 0.3034 0.82768688 1.000 1.000 0.798 ! regulation of antigen receptor-mediated signaling pathway GO:0050854 26 26 1.000 0.3034 0.82669206 0.3034 1.000 0.769 ! response to electrical stimulus GO:0051602 27 26 1.000 0.3034 0.82569964 1.000 1.000 0.800 ! regulation of focal adhesion assembly GO:0051893 26 26 1.000 0.3034 0.82470959 1.000 1.000 0.824 GO:0090109|regulation of cell-substrate junction assembly, ! prostate gland epithelium morphogenesis GO:0060740 26 26 1.000 0.3034 0.82372191 1.000 1.000 0.843 ! positive regulation of protein tyrosine kinase activity GO:0061098 26 26 1.000 0.3034 0.8227366 0.3034 1.000 0.802 ! negative regulation of stress-activated protein kinase signaling cascade GO:0070303 26 26 1.000 0.3034 0.83879 0.3034 1.000 0.744 GO:0032873|negative regulation of stress-activated MAPK cascade, ! regulation of cell-substrate junction assembly GO:0090109 26 26 1.000 0.3034 0.82470959 1.000 1.000 0.824 GO:0051893|regulation of focal adhesion assembly, ! positive regulation of lipid kinase activity GO:0090218 26 26 1.000 0.3034 0.82175364 1.000 1.000 0.833 ! G-protein signaling, coupled to cyclic nucleotide second messenger GO:0007187 140 140 3.000 0.30469028 0.82426355 0.85815951 1.000 0.946 ! regulation of response to biotic stimulus GO:0002831 82 81 2.000 0.30785374 0.83182889 0.30785374 1.000 0.875 ! positive regulation of calcium ion transport into cytosol GO:0010524 27 27 1.000 0.31302682 0.84479977 1.000 1.000 0.827 ! regulation of macrophage derived foam cell differentiation GO:0010743 27 27 1.000 0.31302682 0.84379525 0.31302682 1.000 0.839 ! calcium ion-dependent exocytosis GO:0017156 28 27 1.000 0.31302682 0.84279312 0.31302682 1.000 0.584 ! chondroitin sulfate biosynthetic process GO:0030206 27 27 1.000 0.31302682 0.84179336 0.31302682 1.000 0.677 ! hair follicle morphogenesis GO:0031069 27 27 1.000 0.31302682 0.84079598 1.000 1.000 0.776 ! positive regulation of Rac GTPase activity GO:0032855 27 27 1.000 0.31302682 0.83980095 0.31302682 1.000 0.723 ! eye photoreceptor cell development GO:0042462 27 27 1.000 0.31302682 0.83880828 0.31302682 1.000 0.710 ! positive regulation of tyrosine phosphorylation of Stat3 protein GO:0042517 27 27 1.000 0.31302682 0.83781795 1.000 1.000 0.830 ! peptide biosynthetic process GO:0043043 27 27 1.000 0.31302682 0.83682996 1.000 1.000 0.562 ! regulation of phosphatidylinositol 3-kinase activity GO:0043551 27 27 1.000 0.31302682 0.83584429 1.000 1.000 0.836 ! positive regulation of fatty acid metabolic process GO:0045923 27 27 1.000 0.31302682 0.83486094 1.000 1.000 0.845 ! sphingoid biosynthetic process GO:0046520 27 27 1.000 0.31302682 0.83387991 0.31302682 1.000 0.697 ! positive regulation of receptor-mediated endocytosis GO:0048260 27 27 1.000 0.31302682 0.83290118 1.000 1.000 0.826 ! vesicle docking GO:0048278 27 27 1.000 0.31302682 0.83192474 0.31302682 1.000 0.529 ! detection of mechanical stimulus GO:0050982 27 27 1.000 0.31302682 0.83095059 1.000 1.000 0.812 ! growth hormone receptor signaling pathway GO:0060396 27 27 1.000 0.31302682 0.82997872 1.000 1.000 0.767 ! nucleotide-binding oligomerization domain containing signaling pathway GO:0070423 27 27 1.000 0.31302682 0.82900912 0.31302682 1.000 0.774 ! defense response to virus GO:0051607 147 143 3.000 0.31601034 0.835934 0.31601034 1.000 0.946 ! regulation of glucose transport GO:0010827 85 83 2.000 0.31802088 0.84027195 0.68526245 1.000 0.946 ! positive regulation of innate immune response GO:0045089 144 144 3.000 0.31978607 0.8439523 0.31978607 1.000 0.946 ! myeloid leukocyte mediated immunity GO:0002444 28 28 1.000 0.32252113 0.85018071 0.32252113 1.000 0.814 ! leukotriene biosynthetic process GO:0019370 28 28 1.000 0.32252113 0.84919328 0.32252113 1.000 0.645 GO:0043450|alkene biosynthetic process, ! regulation of histone acetylation GO:0035065 28 28 1.000 0.32252113 0.84820813 1.000 1.000 0.814 ! alkene biosynthetic process GO:0043450 28 28 1.000 0.32252113 0.84919328 0.32252113 1.000 0.645 GO:0019370|leukotriene biosynthetic process, ! regulation of muscle adaptation GO:0043502 28 28 1.000 0.32252113 0.84722527 1.000 1.000 0.845 ! multicellular organismal catabolic process GO:0044243 28 28 1.000 0.32252113 0.84624469 0.32252113 1.000 0.434 ! positive regulation of glucose import GO:0046326 29 28 1.000 0.32252113 0.84526637 0.32252113 1.000 0.782 ! brain morphogenesis GO:0048854 28 28 1.000 0.32252113 0.84429031 0.32252113 1.000 0.815 ! regulation of defense response to virus by virus GO:0050690 28 28 1.000 0.32252113 0.84331651 0.32252113 1.000 0.634 ! brown fat cell differentiation GO:0050873 28 28 1.000 0.32252113 0.84234495 1.000 1.000 0.659 ! positive regulation of small GTPase mediated signal transduction GO:0051057 28 28 1.000 0.32252113 0.84137562 1.000 1.000 0.781 ! neuron apoptosis GO:0051402 28 28 1.000 0.32252113 0.84040852 0.32252113 1.000 0.724 ! prostate gland morphogenesis GO:0060512 28 28 1.000 0.32252113 0.83944364 1.000 1.000 0.832 ! regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061418 28 28 1.000 0.32252113 0.83848098 0.32252113 1.000 0.717 ! cellular response to growth hormone stimulus GO:0071378 28 28 1.000 0.32252113 0.83752052 1.000 1.000 0.779 ! regulation of cellular response to growth factor stimulus GO:0090287 28 28 1.000 0.32252113 0.83656226 1.000 1.000 0.810 ! activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919 84 84 2.000 0.32309168 0.8370844 0.68962596 1.000 0.871 ! leukocyte chemotaxis GO:0030595 84 84 2.000 0.32309168 0.83612882 0.32309168 1.000 0.880 ! pigmentation GO:0043473 84 84 2.000 0.32309168 0.83517542 0.68962596 1.000 0.872 ! regulation of embryonic development GO:0045995 85 84 2.000 0.32309168 0.8342242 0.68962596 1.000 0.890 ! cellular component assembly involved in morphogenesis GO:0010927 147 145 3.000 0.32356237 0.83448906 0.32356237 1.000 0.946 ! positive regulation of cAMP metabolic process GO:0030816 85 85 2.000 0.328153 0.84536689 1.000 1.000 0.877 GO:0030819|positive regulation of cAMP biosynthetic process, ! positive regulation of cAMP biosynthetic process GO:0030819 85 85 2.000 0.328153 0.84536689 1.000 1.000 0.877 GO:0030816|positive regulation of cAMP metabolic process, ! activation of cysteine-type endopeptidase activity GO:0097202 85 85 2.000 0.328153 0.84440733 0.69392921 1.000 0.871 ! female pregnancy GO:0007565 147 147 3.000 0.33111516 0.85106356 0.60469701 1.000 0.946 ! branching morphogenesis of a tube GO:0048754 147 147 3.000 0.33111516 0.85009973 0.60469701 1.000 0.946 ! regulation of systemic arterial blood pressure by hormone GO:0001990 29 29 1.000 0.33188476 0.8511117 1.000 1.000 0.835 ! myeloid cell activation involved in immune response GO:0002275 29 29 1.000 0.33188476 0.85014999 0.33188476 1.000 0.813 ! androgen metabolic process GO:0008209 29 29 1.000 0.33188476 0.84919045 0.33188476 1.000 0.802 ! histone mRNA metabolic process GO:0008334 29 29 1.000 0.33188476 0.84823308 0.33188476 1.000 0.571 ! bicarbonate transport GO:0015701 29 29 1.000 0.33188476 0.84727786 0.33188476 1.000 0.396 ! melanocyte differentiation GO:0030318 29 29 1.000 0.33188476 0.84632479 0.33188476 1.000 0.764 ! positive regulation of transporter activity GO:0032411 29 29 1.000 0.33188476 0.84537387 1.000 1.000 0.793 ! embryonic hindlimb morphogenesis GO:0035116 29 29 1.000 0.33188476 0.84442508 0.33188476 1.000 0.809 ! positive regulation of multicellular organism growth GO:0040018 29 29 1.000 0.33188476 0.84347841 1.000 1.000 0.855 ! hydrogen peroxide metabolic process GO:0042743 29 29 1.000 0.33188476 0.84253387 0.33188476 1.000 0.771 ! positive regulation of DNA binding GO:0043388 29 29 1.000 0.33188476 0.84159143 1.000 1.000 0.855 ! regulated secretory pathway GO:0045055 29 29 1.000 0.33188476 0.84065111 0.33188476 1.000 0.778 ! intermediate filament cytoskeleton organization GO:0045104 29 29 1.000 0.33188476 0.83971288 0.33188476 1.000 0.605 ! face morphogenesis GO:0060325 29 29 1.000 0.33188476 0.83877675 0.33188476 1.000 0.797 ! cell fate commitment involved in formation of primary germ layers GO:0060795 29 29 1.000 0.33188476 0.8378427 1.000 1.000 0.828 ! chromosome organization involved in meiosis GO:0070192 29 29 1.000 0.33188476 0.83691073 0.33188476 1.000 0.682 ! negative regulation of peptide hormone secretion GO:0090278 29 29 1.000 0.33188476 0.83598082 1.000 1.000 0.808 ! regulation of leukocyte migration GO:0002685 87 86 2.000 0.33320414 0.83837268 0.69817303 1.000 0.890 ! proteoglycan metabolic process GO:0006029 86 86 2.000 0.33320414 0.83744322 0.33320414 1.000 0.946 ! ovulation cycle GO:0042698 86 86 2.000 0.33320414 0.83651582 0.33320414 1.000 0.881 ! cellular respiration GO:0045333 149 148 3.000 0.33489093 0.83982051 0.60839298 1.000 0.946 ! response to acid GO:0001101 90 87 2.000 0.33824441 0.84729291 0.33824441 1.000 0.876 ! triglyceride metabolic process GO:0006641 87 87 2.000 0.33824441 0.84635771 0.33824441 1.000 0.879 ! negative regulation of catabolic process GO:0009895 87 87 2.000 0.33824441 0.84542457 0.33824441 1.000 0.880 ! negative regulation of peptide secretion GO:0002792 30 30 1.000 0.34111948 0.85167165 1.000 1.000 0.814 ! mitotic cell cycle spindle assembly checkpoint GO:0007094 30 30 1.000 0.34111948 0.85073471 1.000 1.000 0.709 ! negative regulation of gliogenesis GO:0014014 30 30 1.000 0.34111948 0.84979984 0.34111948 1.000 0.835 ! long-chain fatty acid transport GO:0015909 30 30 1.000 0.34111948 0.84886702 1.000 1.000 0.807 ! extracellular matrix disassembly GO:0022617 30 30 1.000 0.34111948 0.84793624 0.34111948 1.000 0.465 ! positive regulation of bone mineralization GO:0030501 30 30 1.000 0.34111948 0.84700751 0.34111948 1.000 0.852 ! negative regulation of transcription factor import into nucleus GO:0042992 30 30 1.000 0.34111948 0.8460808 0.34111948 1.000 0.796 ! intermediate filament-based process GO:0045103 30 30 1.000 0.34111948 0.84515613 0.34111948 1.000 0.591 ! positive regulation of nitric oxide biosynthetic process GO:0045429 30 30 1.000 0.34111948 0.84423347 1.000 1.000 0.860 ! negative regulation of behavior GO:0048521 30 30 1.000 0.34111948 0.84331282 1.000 1.000 0.861 ! chondroitin sulfate proteoglycan biosynthetic process GO:0050650 30 30 1.000 0.34111948 0.84239418 0.34111948 1.000 0.689 ! positive regulation of phagocytosis GO:0050766 30 30 1.000 0.34111948 0.84147754 1.000 1.000 0.820 ! pigment cell differentiation GO:0050931 30 30 1.000 0.34111948 0.84056289 0.34111948 1.000 0.775 ! negative regulation of response to cytokine stimulus GO:0060761 30 30 1.000 0.34111948 0.83965022 1.000 1.000 0.825 ! protein-lipid complex subunit organization GO:0071825 30 30 1.000 0.34111948 0.83873954 0.34111948 1.000 0.847 GO:0071827|plasma lipoprotein particle organization, ! plasma lipoprotein particle organization GO:0071827 30 30 1.000 0.34111948 0.83873954 0.34111948 1.000 0.847 GO:0071825|protein-lipid complex subunit organization, ! organelle transport along microtubule GO:0072384 30 30 1.000 0.34111948 0.83783083 0.34111948 1.000 0.726 ! regulation of peptidyl-lysine acetylation GO:2000756 30 30 1.000 0.34111948 0.83692409 1.000 1.000 0.828 ! energy reserve metabolic process GO:0006112 150 150 3.000 0.34243947 0.83925434 0.34243947 1.000 0.946 ! insulin receptor signaling pathway GO:0008286 151 150 3.000 0.34243947 0.83834802 0.6157063 1.000 0.946 ! positive regulation of GTPase activity GO:0043547 150 150 3.000 0.34243947 0.83744366 0.6157063 1.000 0.946 ! negative regulation of cell adhesion GO:0007162 88 88 2.000 0.34327316 0.83857785 1.000 1.000 0.878 ! morphogenesis of a branching epithelium GO:0061138 151 151 3.000 0.34621153 0.84484557 0.61932368 1.000 0.946 ! negative regulation of protein serine/threonine kinase activity GO:0071901 89 89 2.000 0.34828974 0.84900304 0.34828974 1.000 0.946 ! cytoplasmic pattern recognition receptor signaling pathway GO:0002753 31 31 1.000 0.35022707 0.85280855 0.35022707 1.000 0.806 ! salivary gland morphogenesis GO:0007435 31 31 1.000 0.35022707 0.85189352 1.000 1.000 0.845 ! positive regulation of glucose metabolic process GO:0010907 31 31 1.000 0.35022707 0.85098045 0.35022707 1.000 0.831 ! regulation of interferon-beta production GO:0032648 31 31 1.000 0.35022707 0.85006933 0.35022707 1.000 0.779 ! positive regulation of interferon-gamma production GO:0032729 32 31 1.000 0.35022707 0.84916017 1.000 1.000 0.855 ! positive regulation of tumor necrosis factor production GO:0032760 31 31 1.000 0.35022707 0.84825295 1.000 1.000 0.867 ! membrane protein proteolysis GO:0033619 31 31 1.000 0.35022707 0.84734766 0.35022707 1.000 0.738 ! embryonic eye morphogenesis GO:0048048 31 31 1.000 0.35022707 0.8464443 0.35022707 1.000 0.849 ! spindle assembly checkpoint GO:0071173 31 31 1.000 0.35022707 0.84554287 1.000 1.000 0.717 ! positive regulation of neural precursor cell proliferation GO:2000179 31 31 1.000 0.35022707 0.84464336 1.000 1.000 0.851 ! positive regulation of response to external stimulus GO:0032103 153 153 3.000 0.35374956 0.85223193 0.88177823 1.000 0.946 ! lysosome organization GO:0007040 32 32 1.000 0.35920926 0.86446645 0.35920926 1.000 0.697 ! positive regulation of cell morphogenesis involved in differentiation GO:0010770 32 32 1.000 0.35920926 0.86354973 0.35920926 1.000 0.853 ! positive regulation of glucose transport GO:0010828 33 32 1.000 0.35920926 0.86263496 0.35920926 1.000 0.807 ! oligodendrocyte development GO:0014003 34 32 1.000 0.35920926 0.86172212 0.35920926 1.000 0.820 ! response to activity GO:0014823 32 32 1.000 0.35920926 0.8608112 1.000 1.000 0.823 ! sperm motility GO:0030317 32 32 1.000 0.35920926 0.85990222 0.35920926 1.000 0.471 ! organ growth GO:0035265 33 32 1.000 0.35920926 0.85899515 1.000 1.000 0.859 ! regulation of tyrosine phosphorylation of Stat3 protein GO:0042516 32 32 1.000 0.35920926 0.85808999 1.000 1.000 0.831 ! positive regulation of transcription factor import into nucleus GO:0042993 32 32 1.000 0.35920926 0.85718674 1.000 1.000 0.839 ! ATP-dependent chromatin remodeling GO:0043044 32 32 1.000 0.35920926 0.85628538 0.35920926 1.000 0.582 ! regulation of lipid kinase activity GO:0043550 32 32 1.000 0.35920926 0.85538592 1.000 1.000 0.824 ! negative regulation of viral genome replication GO:0045071 32 32 1.000 0.35920926 0.85448835 0.35920926 1.000 0.740 ! negative regulation of mitotic metaphase/anaphase transition GO:0045841 32 32 1.000 0.35920926 0.85359266 1.000 1.000 0.729 ! response to growth hormone stimulus GO:0060416 32 32 1.000 0.35920926 0.85269885 1.000 1.000 0.796 ! trabecula morphogenesis GO:0061383 32 32 1.000 0.35920926 0.8518069 1.000 1.000 0.849 ! positive regulation of biomineral tissue development GO:0070169 32 32 1.000 0.35920926 0.85091682 0.35920926 1.000 0.855 ! cochlea development GO:0090102 32 32 1.000 0.35920926 0.8500286 1.000 1.000 0.829 ! positive regulation of cyclic nucleotide biosynthetic process GO:0030804 92 92 2.000 0.36326036 0.8587187 1.000 1.000 0.946 ! lipid transport GO:0006869 156 156 3.000 0.36503639 0.86201823 0.63701894 1.000 0.946 ! regulation of organ formation GO:0003156 33 33 1.000 0.36806779 0.8682723 1.000 1.000 0.864 ! pyruvate metabolic process GO:0006090 33 33 1.000 0.36806779 0.86736973 0.36806779 1.000 0.734 ! peroxisome organization GO:0007031 33 33 1.000 0.36806779 0.86646904 0.36806779 1.000 0.724 ! C21-steroid hormone metabolic process GO:0008207 33 33 1.000 0.36806779 0.86557021 0.36806779 1.000 0.787 ! phospholipid transport GO:0015914 33 33 1.000 0.36806779 0.86467325 0.36806779 1.000 0.768 ! peptidyl-threonine phosphorylation GO:0018107 33 33 1.000 0.36806779 0.86377814 0.36806779 1.000 0.808 ! ventral spinal cord development GO:0021517 33 33 1.000 0.36806779 0.86288488 1.000 1.000 0.784 ! developmental induction GO:0031128 33 33 1.000 0.36806779 0.86199347 0.36806779 1.000 0.853 ! positive regulation of interleukin-6 production GO:0032755 33 33 1.000 0.36806779 0.8611039 1.000 1.000 0.857 ! regulation of S phase GO:0033261 33 33 1.000 0.36806779 0.86021617 0.36806779 1.000 0.713 ! photoreceptor cell development GO:0042461 33 33 1.000 0.36806779 0.85933026 0.36806779 1.000 0.735 ! positive regulation of blood pressure GO:0045777 33 33 1.000 0.36806779 0.85844617 1.000 1.000 0.852 ! negative regulation of viral reproduction GO:0048525 33 33 1.000 0.36806779 0.85756391 0.36806779 1.000 0.751 ! dendrite morphogenesis GO:0048813 33 33 1.000 0.36806779 0.85668345 0.36806779 1.000 0.730 ! protein autoubiquitination GO:0051865 33 33 1.000 0.36806779 0.8558048 0.36806779 1.000 0.485 ! head morphogenesis GO:0060323 33 33 1.000 0.36806779 0.85492795 0.36806779 1.000 0.815 ! regulation of pathway-restricted SMAD protein phosphorylation GO:0060393 33 33 1.000 0.36806779 0.8540529 0.36806779 1.000 0.845 ! response to transforming growth factor beta stimulus GO:0071559 33 33 1.000 0.36806779 0.85317963 0.36806779 1.000 0.828 ! regulation of Rho GTPase activity GO:0032319 93 93 2.000 0.36822226 0.85266584 0.72628316 1.000 0.946 ! cyclic-nucleotide-mediated signaling GO:0019935 158 158 3.000 0.37254375 0.86179253 0.88978067 1.000 0.946 ! regulation of transforming growth factor beta receptor signaling pathway GO:0017015 94 94 2.000 0.37316907 0.86235911 0.37316907 1.000 0.946 ! positive regulation of nucleotide biosynthetic process GO:0030810 94 94 2.000 0.37316907 0.86148094 1.000 1.000 0.946 ! odontogenesis GO:0042476 94 94 2.000 0.37316907 0.86060456 0.73008009 1.000 0.946 ! regulation of protein catabolic process GO:0042176 159 159 3.000 0.37629134 0.86692323 0.64732423 1.000 0.946 ! GPI anchor biosynthetic process GO:0006506 34 34 1.000 0.37680434 0.8672238 0.37680434 1.000 0.421 ! leukotriene metabolic process GO:0006691 34 34 1.000 0.37680434 0.86634427 0.37680434 1.000 0.727 ! cholesterol biosynthetic process GO:0006695 34 34 1.000 0.37680434 0.86546651 0.37680434 1.000 0.682 ! membrane docking GO:0022406 34 34 1.000 0.37680434 0.86459053 0.37680434 1.000 0.654 ! positive regulation of histone modification GO:0031058 34 34 1.000 0.37680434 0.86371633 1.000 1.000 0.849 ! negative regulation of type I interferon production GO:0032480 34 34 1.000 0.37680434 0.86284389 0.37680434 1.000 0.666 ! collagen metabolic process GO:0032963 34 34 1.000 0.37680434 0.86197321 0.37680434 1.000 0.474 ! cellular polysaccharide biosynthetic process GO:0033692 34 34 1.000 0.37680434 0.86110428 0.37680434 1.000 0.753 ! cell-cell signaling involved in cell fate commitment GO:0045168 34 34 1.000 0.37680434 0.86023711 0.37680434 1.000 0.856 ! positive regulation of mitosis GO:0045840 34 34 1.000 0.37680434 0.85937168 0.37680434 1.000 0.837 GO:0051785|positive regulation of nuclear division, ! positive regulation of nuclear division GO:0051785 34 34 1.000 0.37680434 0.85937168 0.37680434 1.000 0.837 GO:0045840|positive regulation of mitosis, ! cellular response to carbohydrate stimulus GO:0071322 34 34 1.000 0.37680434 0.85850799 0.37680434 1.000 0.836 ! cellular response to glucagon stimulus GO:0071377 34 34 1.000 0.37680434 0.85764603 0.37680434 1.000 0.593 ! negative regulation of chromosome organization GO:2001251 34 34 1.000 0.37680434 0.8567858 1.000 1.000 0.855 ! glycosaminoglycan biosynthetic process GO:0006024 95 95 2.000 0.37810028 0.85887107 0.37810028 1.000 0.946 ! positive regulation of cyclic nucleotide metabolic process GO:0030801 95 95 2.000 0.37810028 0.85801134 1.000 1.000 0.946 ! intracellular receptor mediated signaling pathway GO:0030522 160 160 3.000 0.38003446 0.86153812 0.38003446 1.000 0.946 ! aminoglycan biosynthetic process GO:0006023 96 96 2.000 0.38301536 0.86742839 0.38301536 1.000 0.946 ! DNA alkylation GO:0006305 35 35 1.000 0.38542059 0.87200448 0.38542059 1.000 0.761 GO:0006306|DNA methylation, ! DNA methylation GO:0006306 35 35 1.000 0.38542059 0.87200448 0.38542059 1.000 0.761 GO:0006305|DNA alkylation, ! male meiosis GO:0007140 38 35 1.000 0.38542059 0.87113508 0.38542059 1.000 0.600 ! salivary gland development GO:0007431 35 35 1.000 0.38542059 0.87026742 1.000 1.000 0.846 ! embryo implantation GO:0007566 35 35 1.000 0.38542059 0.86940148 1.000 1.000 0.686 ! phototransduction GO:0007602 35 35 1.000 0.38542059 0.86853727 0.38542059 1.000 0.577 ! regulation of interleukin-1 beta production GO:0032651 35 35 1.000 0.38542059 0.86767477 1.000 1.000 0.860 ! regulation of transcription elongation, DNA-dependent GO:0032784 37 35 1.000 0.38542059 0.86681398 0.38542059 1.000 0.582 ! cellular alkene metabolic process GO:0043449 35 35 1.000 0.38542059 0.86595489 0.38542059 1.000 0.737 ! negative regulation of muscle cell differentiation GO:0051148 35 35 1.000 0.38542059 0.86509751 1.000 1.000 0.809 ! neuron death GO:0070997 35 35 1.000 0.38542059 0.86424183 0.38542059 1.000 0.755 ! nucleotide biosynthetic process GO:0009165 163 162 3.000 0.38750615 0.86805973 0.65739731 1.000 0.946 ! cell projection assembly GO:0030031 162 162 3.000 0.38750615 0.86720281 0.65739731 1.000 0.946 ! regulation of Ras GTPase activity GO:0032318 162 162 3.000 0.38750615 0.86634758 0.8957923 1.000 0.946 ! chromatin remodeling GO:0006338 97 97 2.000 0.38791383 0.86640459 0.38791383 1.000 0.946 ! carbohydrate transport GO:0008643 97 97 2.000 0.38791383 0.86555183 0.74115898 1.000 0.757 ! regulation of protein binding GO:0043393 97 97 2.000 0.38791383 0.86470074 0.74115898 1.000 0.946 ! positive regulation of lymphocyte proliferation GO:0050671 97 97 2.000 0.38791383 0.86385133 1.000 1.000 0.891 ! carboxylic acid transport GO:0046942 165 163 3.000 0.39123414 0.87039038 0.66070368 1.000 0.946 ! positive regulation of Ras GTPase activity GO:0032320 98 98 2.000 0.39279521 0.87300661 0.74475036 1.000 0.946 ! positive regulation of mononuclear cell proliferation GO:0032946 98 98 2.000 0.39279521 0.87215156 1.000 1.000 0.891 ! positive regulation of nucleotide metabolic process GO:0045981 98 98 2.000 0.39279521 0.87129818 1.000 1.000 0.946 ! very long-chain fatty acid metabolic process GO:0000038 36 36 1.000 0.39391819 0.87293504 1.000 1.000 0.796 ! GPI anchor metabolic process GO:0006505 36 36 1.000 0.39391819 0.87208256 0.39391819 1.000 0.444 ! reciprocal meiotic recombination GO:0007131 36 36 1.000 0.39391819 0.87123175 0.39391819 1.000 0.755 GO:0035825|reciprocal DNA recombination, ! response to gamma radiation GO:0010332 36 36 1.000 0.39391819 0.8703826 0.39391819 1.000 0.828 ! peptidyl-threonine modification GO:0018210 36 36 1.000 0.39391819 0.8695351 0.39391819 1.000 0.813 ! ER-associated protein catabolic process GO:0030433 36 36 1.000 0.39391819 0.86868925 0.39391819 1.000 0.368 ! positive regulation of type I interferon production GO:0032481 36 36 1.000 0.39391819 0.86784504 0.39391819 1.000 0.807 ! cellular pigmentation GO:0033059 36 36 1.000 0.39391819 0.86700247 0.39391819 1.000 0.812 ! cellular response to UV GO:0034644 37 36 1.000 0.39391819 0.86616154 1.000 1.000 0.808 ! cellular response to drug GO:0035690 36 36 1.000 0.39391819 0.86532223 0.39391819 1.000 0.846 ! reciprocal DNA recombination GO:0035825 36 36 1.000 0.39391819 0.87123175 0.39391819 1.000 0.755 GO:0007131|reciprocal meiotic recombination, ! phosphatidylcholine metabolic process GO:0046470 36 36 1.000 0.39391819 0.86448456 0.39391819 1.000 0.736 ! endocrine process GO:0050886 36 36 1.000 0.39391819 0.8636485 1.000 1.000 0.857 ! organic acid transport GO:0015849 167 165 3.000 0.398673 0.87322869 0.66723987 1.000 0.946 ! positive regulation of mesenchymal cell proliferation GO:0002053 37 37 1.000 0.40229877 0.8803198 1.000 1.000 0.848 ! regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 37 37 1.000 0.40229877 0.87947089 1.000 1.000 0.863 ! vesicle coating GO:0006901 37 37 1.000 0.40229877 0.87862361 0.40229877 1.000 0.691 ! axon cargo transport GO:0008088 37 37 1.000 0.40229877 0.87777797 0.40229877 1.000 0.762 ! regulation of Notch signaling pathway GO:0008593 37 37 1.000 0.40229877 0.87693395 1.000 1.000 0.772 ! fatty acid transport GO:0015908 37 37 1.000 0.40229877 0.87609156 1.000 1.000 0.840 ! polyol metabolic process GO:0019751 37 37 1.000 0.40229877 0.87525078 0.40229877 1.000 0.690 ! digestive system process GO:0022600 37 37 1.000 0.40229877 0.87441161 0.40229877 1.000 0.790 ! collagen fibril organization GO:0030199 37 37 1.000 0.40229877 0.87357405 0.40229877 1.000 0.753 ! neutrophil chemotaxis GO:0030593 37 37 1.000 0.40229877 0.87273809 0.40229877 1.000 0.795 ! actin cytoskeleton reorganization GO:0031532 37 37 1.000 0.40229877 0.87190374 0.40229877 1.000 0.746 ! forelimb morphogenesis GO:0035136 37 37 1.000 0.40229877 0.87107097 0.40229877 1.000 0.766 ! retrograde transport, endosome to Golgi GO:0042147 37 37 1.000 0.40229877 0.8702398 0.40229877 1.000 0.283 ! negative regulation of DNA binding GO:0043392 37 37 1.000 0.40229877 0.86941021 1.000 1.000 0.825 ! regulation of transcription from RNA polymerase II promoter in response to stress GO:0043618 37 37 1.000 0.40229877 0.8685822 0.40229877 1.000 0.801 ! positive regulation of mitotic cell cycle GO:0045931 37 37 1.000 0.40229877 0.86775577 1.000 1.000 0.846 ! regulation of nuclear mRNA splicing, via spliceosome GO:0048024 37 37 1.000 0.40229877 0.8669309 0.40229877 1.000 0.522 ! lung alveolus development GO:0048286 37 37 1.000 0.40229877 0.86610761 1.000 1.000 0.843 ! face development GO:0060324 37 37 1.000 0.40229877 0.86528587 0.40229877 1.000 0.817 ! digestion GO:0007586 100 100 2.000 0.40250486 0.86490856 0.40250486 1.000 0.794 ! negative regulation of protein transport GO:0051224 101 100 2.000 0.40250486 0.86408951 0.75178491 1.000 0.946 ! epidermal cell differentiation GO:0009913 101 101 2.000 0.40733226 0.87362558 0.75522944 1.000 0.700 ! negative regulation of cell cycle process GO:0010948 101 101 2.000 0.40733226 0.87279985 1.000 1.000 0.946 ! positive regulation of leukocyte proliferation GO:0070665 101 101 2.000 0.40733226 0.87197568 1.000 1.000 0.891 ! microtubule-based movement GO:0007018 168 168 3.000 0.40978443 0.87639745 0.40978443 1.000 0.783 ! regulation of Rho protein signal transduction GO:0035023 170 168 3.000 0.40978443 0.87557144 0.67685386 1.000 0.946 ! vitamin A metabolic process GO:0006776 38 38 1.000 0.41056392 0.87641094 0.41056392 1.000 0.771 ! mitochondrial membrane organization GO:0007006 39 38 1.000 0.41056392 0.87558647 1.000 1.000 0.789 ! telencephalon cell migration GO:0022029 38 38 1.000 0.41056392 0.87476355 1.000 1.000 0.878 ! regulation of axon extension GO:0030516 38 38 1.000 0.41056392 0.87394217 0.41056392 1.000 0.804 ! positive regulation of fibroblast proliferation GO:0048146 38 38 1.000 0.41056392 0.87312234 0.41056392 1.000 0.845 ! developmental cell growth GO:0048588 38 38 1.000 0.41056392 0.87230405 0.41056392 1.000 0.814 ! negative regulation of protein secretion GO:0050709 39 38 1.000 0.41056392 0.87148728 1.000 1.000 0.830 ! humoral immune response GO:0006959 102 102 2.000 0.41214082 0.87401613 0.41214082 1.000 0.780 ! gland morphogenesis GO:0022612 102 102 2.000 0.41214082 0.87319929 0.75862636 1.000 0.891 ! response to interferon-gamma GO:0034341 102 102 2.000 0.41214082 0.87238398 0.75862636 1.000 0.946 ! cellular response to biotic stimulus GO:0071216 102 102 2.000 0.41214082 0.87157019 0.41214082 1.000 0.891 ! regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO:0090092 169 169 3.000 0.41347469 0.87357607 0.41347469 1.000 0.946 ! fertilization GO:0009566 104 103 2.000 0.41693014 0.88005644 0.41693014 1.000 0.740 ! regulation of multi-organism process GO:0043900 104 103 2.000 0.41693014 0.87923779 0.41693014 1.000 0.946 ! cellular glucose homeostasis GO:0001678 39 39 1.000 0.41871524 0.88218165 0.41871524 1.000 0.850 ! prostate gland development GO:0030850 39 39 1.000 0.41871524 0.88136254 1.000 1.000 0.839 ! regulation of interleukin-1 production GO:0032652 39 39 1.000 0.41871524 0.88054495 1.000 1.000 0.866 ! termination of G-protein coupled receptor signaling pathway GO:0038032 39 39 1.000 0.41871524 0.87972888 0.41871524 1.000 0.119 ! cellular component maintenance GO:0043954 39 39 1.000 0.41871524 0.87891431 0.41871524 1.000 0.732 ! positive regulation of ossification GO:0045778 39 39 1.000 0.41871524 0.87810125 0.41871524 1.000 0.869 ! regulation of receptor-mediated endocytosis GO:0048259 39 39 1.000 0.41871524 0.8772897 1.000 1.000 0.853 ! positive regulation of developmental growth GO:0048639 39 39 1.000 0.41871524 0.87647965 0.41871524 1.000 0.851 ! negative regulation of coagulation GO:0050819 39 39 1.000 0.41871524 0.87567109 0.41871524 1.000 0.796 ! embryonic epithelial tube formation GO:0001838 104 104 2.000 0.42169982 0.8811 0.42169982 1.000 0.946 ! detection of external stimulus GO:0009581 104 104 2.000 0.42169982 0.88028867 0.76527997 1.000 0.946 ! lipid localization GO:0010876 172 172 3.000 0.42450129 0.88532146 0.68932076 1.000 0.946 ! lipid modification GO:0030258 105 105 2.000 0.42644951 0.88856714 0.42644951 1.000 0.946 ! alcohol biosynthetic process GO:0046165 105 105 2.000 0.42644951 0.88775119 0.76853796 1.000 0.946 ! epithelial tube formation GO:0072175 105 105 2.000 0.42644951 0.88693674 0.42644951 1.000 0.946 ! purine base metabolic process GO:0006144 40 40 1.000 0.42675429 0.88675708 0.42675429 1.000 0.827 ! transcription from RNA polymerase III promoter GO:0006383 40 40 1.000 0.42675429 0.88594503 0.42675429 1.000 0.237 ! water transport GO:0006833 40 40 1.000 0.42675429 0.88513447 0.42675429 1.000 0.781 ! bile acid metabolic process GO:0008206 40 40 1.000 0.42675429 0.88432538 0.42675429 1.000 0.720 ! aspartate family amino acid metabolic process GO:0009066 40 40 1.000 0.42675429 0.88351778 0.42675429 1.000 0.823 ! sterol biosynthetic process GO:0016126 40 40 1.000 0.42675429 0.88271165 0.42675429 1.000 0.674 ! regulation of mitotic metaphase/anaphase transition GO:0030071 40 40 1.000 0.42675429 0.88190699 1.000 1.000 0.796 ! positive regulation of actin filament polymerization GO:0030838 41 40 1.000 0.42675429 0.8811038 0.42675429 1.000 0.778 ! multicellular organismal macromolecule metabolic process GO:0044259 40 40 1.000 0.42675429 0.88030207 0.42675429 1.000 0.613 ! developmental pigmentation GO:0048066 40 40 1.000 0.42675429 0.87950179 0.42675429 1.000 0.821 ! regulation of dendrite morphogenesis GO:0048814 41 40 1.000 0.42675429 0.87870297 0.42675429 1.000 0.811 ! mesoderm development GO:0007498 106 106 2.000 0.43117885 0.88700766 0.7717509 1.000 0.946 ! response to ionizing radiation GO:0010212 107 106 2.000 0.43117885 0.88620349 0.43117885 1.000 0.946 ! cell chemotaxis GO:0060326 106 106 2.000 0.43117885 0.88540077 0.43117885 1.000 0.946 ! membrane budding GO:0006900 41 41 1.000 0.4346826 0.89178774 0.4346826 1.000 0.733 ! body morphogenesis GO:0010171 41 41 1.000 0.4346826 0.89098142 0.4346826 1.000 0.818 ! regulation of mesenchymal cell proliferation GO:0010464 41 41 1.000 0.4346826 0.89017656 1.000 1.000 0.861 ! regulation of epithelial to mesenchymal transition GO:0010717 41 41 1.000 0.4346826 0.88937315 0.4346826 1.000 0.869 ! cell differentiation in spinal cord GO:0021515 42 41 1.000 0.4346826 0.88857119 1.000 1.000 0.789 ! forebrain cell migration GO:0021885 41 41 1.000 0.4346826 0.88777068 1.000 1.000 0.877 ! regulation of interleukin-8 production GO:0032677 41 41 1.000 0.4346826 0.8869716 1.000 1.000 0.873 ! response to glucagon stimulus GO:0033762 41 41 1.000 0.4346826 0.88617397 0.4346826 1.000 0.705 ! regulation of nitric oxide biosynthetic process GO:0045428 41 41 1.000 0.4346826 0.88537776 1.000 1.000 0.873 ! negative regulation of mitotic cell cycle GO:0045930 41 41 1.000 0.4346826 0.88458299 0.4346826 1.000 0.745 ! organelle fusion GO:0048284 42 41 1.000 0.4346826 0.88378964 0.4346826 1.000 0.726 ! regulation of phagocytosis GO:0050764 41 41 1.000 0.4346826 0.88299771 1.000 1.000 0.853 ! positive regulation of axonogenesis GO:0050772 41 41 1.000 0.4346826 0.88220721 0.4346826 1.000 0.795 ! cellular response to light stimulus GO:0071482 42 41 1.000 0.4346826 0.88141811 1.000 1.000 0.827 ! regulation of plasma lipoprotein particle levels GO:0097006 41 41 1.000 0.4346826 0.88063043 0.4346826 1.000 0.871 ! steroid biosynthetic process GO:0006694 107 107 2.000 0.43588748 0.88228296 0.43588748 1.000 0.946 ! cellular amino acid biosynthetic process GO:0008652 107 107 2.000 0.43588748 0.88149591 0.43588748 1.000 0.946 ! cilium morphogenesis GO:0060271 107 107 2.000 0.43588748 0.88071027 0.43588748 1.000 0.663 ! regulation of protein polymerization GO:0032271 109 108 2.000 0.44057508 0.88938888 0.77804414 1.000 0.946 ! sulfur amino acid metabolic process GO:0000096 42 42 1.000 0.44250169 0.8924834 0.44250169 1.000 0.827 ! retinoid metabolic process GO:0001523 42 42 1.000 0.44250169 0.89169008 0.44250169 1.000 0.769 ! termination of signal transduction GO:0023021 42 42 1.000 0.44250169 0.89089817 0.44250169 1.000 0.241 ! organ regeneration GO:0031100 42 42 1.000 0.44250169 0.89010766 0.44250169 1.000 0.827 ! regulation of DNA-dependent transcription in response to stress GO:0043620 42 42 1.000 0.44250169 0.88931856 0.44250169 1.000 0.812 ! demethylation GO:0070988 42 42 1.000 0.44250169 0.88853086 0.44250169 1.000 0.819 ! organic acid catabolic process GO:0016054 179 177 3.000 0.44271738 0.88817725 0.44271738 1.000 0.946 GO:0046395|carboxylic acid catabolic process, ! nucleobase-containing compound biosynthetic process GO:0034654 178 177 3.000 0.44271738 0.88739195 0.70434718 1.000 0.946 ! carboxylic acid catabolic process GO:0046395 179 177 3.000 0.44271738 0.88817725 0.44271738 1.000 0.946 GO:0016054|organic acid catabolic process, ! regulation of protein stability GO:0031647 110 109 2.000 0.44524134 0.89166265 1.000 1.000 0.946 ! cellular amino acid catabolic process GO:0009063 112 110 2.000 0.44988595 0.90016897 0.44988595 1.000 0.946 ! regulation of pH GO:0006885 43 43 1.000 0.45021307 0.90002913 0.45021307 1.000 0.784 ! inhibition of adenylate cyclase activity by G-protein signaling pathway GO:0007193 43 43 1.000 0.45021307 0.89923615 1.000 1.000 0.806 ! glycolysis GO:0006096 44 44 1.000 0.45781821 0.91362138 0.45781821 1.000 0.793 ! sterol transport GO:0015918 44 44 1.000 0.45781821 0.91281784 0.45781821 1.000 0.849 GO:0030301|cholesterol transport, ! cholesterol transport GO:0030301 44 44 1.000 0.45781821 0.91281784 0.45781821 1.000 0.849 GO:0015918|sterol transport, ! negative regulation of protein polymerization GO:0032272 44 44 1.000 0.45781821 0.91201572 1.000 1.000 0.741 ! regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 44 44 1.000 0.45781821 0.911215 1.000 1.000 0.830 ! exocrine system development GO:0035272 44 44 1.000 0.45781821 0.91041569 1.000 1.000 0.860 ! fluid transport GO:0042044 44 44 1.000 0.45781821 0.90961778 0.45781821 1.000 0.808 ! tube formation GO:0035148 113 113 2.000 0.46368699 0.92047147 0.46368699 1.000 0.946 ! activation of adenylate cyclase activity by G-protein signaling pathway GO:0007189 45 45 1.000 0.46531857 0.92290218 1.000 1.000 0.835 ! detection of light stimulus GO:0009583 45 45 1.000 0.46531857 0.92209545 0.46531857 1.000 0.674 ! positive regulation of insulin secretion GO:0032024 45 45 1.000 0.46531857 0.92129013 1.000 1.000 0.851 ! regulation of monooxygenase activity GO:0032768 45 45 1.000 0.46531857 0.92048621 1.000 1.000 0.859 ! glomerulus development GO:0032835 45 45 1.000 0.46531857 0.91968369 0.46531857 1.000 0.866 ! regulation of glucose import GO:0046324 46 45 1.000 0.46531857 0.91888258 0.46531857 1.000 0.838 ! artery morphogenesis GO:0048844 45 45 1.000 0.46531857 0.91808285 1.000 1.000 0.880 ! kidney morphogenesis GO:0060993 45 45 1.000 0.46531857 0.91728452 0.46531857 1.000 0.881 ! termination of RNA polymerase II transcription GO:0006369 46 46 1.000 0.47271558 0.93105667 0.47271558 1.000 0.394 ! diterpenoid metabolic process GO:0016101 46 46 1.000 0.47271558 0.93024846 0.47271558 1.000 0.802 ! negative regulation of protein import into nucleus GO:0042308 46 46 1.000 0.47271558 0.92944166 0.47271558 1.000 0.827 ! positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 47 46 1.000 0.47271558 0.92863625 1.000 1.000 0.875 ! negative regulation of protein complex disassembly GO:0043242 46 46 1.000 0.47271558 0.92783223 1.000 1.000 0.756 ! dicarboxylic acid metabolic process GO:0043648 46 46 1.000 0.47271558 0.92702961 0.47271558 1.000 0.853 ! regulation of glial cell differentiation GO:0045685 47 46 1.000 0.47271558 0.92622838 0.47271558 1.000 0.873 ! regulation of protein tyrosine kinase activity GO:0061097 46 46 1.000 0.47271558 0.92542852 0.47271558 1.000 0.830 ! regulation of extent of cell growth GO:0061387 46 46 1.000 0.47271558 0.92463005 0.47271558 1.000 0.832 ! cellular response to steroid hormone stimulus GO:0071383 46 46 1.000 0.47271558 0.92383296 1.000 1.000 0.864 ! phagosome maturation GO:0090382 46 46 1.000 0.47271558 0.92303724 0.47271558 1.000 0.774 ! sensory perception of chemical stimulus GO:0007606 116 116 2.000 0.47728336 0.93115438 0.8015354 1.000 0.210 ! cellular carbohydrate catabolic process GO:0044275 116 116 2.000 0.47728336 0.93035373 0.47728336 1.000 0.946 ! ovarian follicle development GO:0001541 47 47 1.000 0.48001068 0.93486615 0.48001068 1.000 0.831 ! transcription-coupled nucleotide-excision repair GO:0006283 47 47 1.000 0.48001068 0.93406369 0.48001068 1.000 0.743 ! synapse assembly GO:0007416 47 47 1.000 0.48001068 0.93326261 1.000 1.000 0.689 ! regulation of adenylate cyclase activity involved in G-protein signaling pathway GO:0010578 47 47 1.000 0.48001068 0.9324629 1.000 1.000 0.840 GO:0010579|positive regulation of adenylate cyclase activity by G-protein signaling pathway, ! positive regulation of adenylate cyclase activity by G-protein signaling pathway GO:0010579 47 47 1.000 0.48001068 0.9324629 1.000 1.000 0.840 GO:0010578|regulation of adenylate cyclase activity involved in G-protein signaling pathway, ! hormone biosynthetic process GO:0042446 47 47 1.000 0.48001068 0.93166456 0.48001068 1.000 0.811 ! endothelial cell migration GO:0043542 47 47 1.000 0.48001068 0.93086758 1.000 1.000 0.822 ! negative regulation of hormone secretion GO:0046888 47 47 1.000 0.48001068 0.93007197 1.000 1.000 0.863 ! neuromuscular process controlling balance GO:0050885 47 47 1.000 0.48001068 0.92927771 0.48001068 1.000 0.826 ! stress-activated MAPK cascade GO:0051403 118 118 2.000 0.48623074 0.94051628 0.80701048 1.000 0.946 ! mitotic sister chromatid segregation GO:0000070 50 48 1.000 0.48720524 0.94159785 1.000 1.000 0.748 ! tRNA aminoacylation for protein translation GO:0006418 48 48 1.000 0.48720524 0.94079581 1.000 1.000 0.782 ! regulation of ARF protein signal transduction GO:0032012 48 48 1.000 0.48720524 0.93999513 0.48720524 1.000 0.00639 ! regulation of viral genome replication GO:0045069 48 48 1.000 0.48720524 0.93919581 0.48720524 1.000 0.813 ! regulation of protein complex assembly GO:0043254 191 190 3.000 0.48895846 0.94177471 0.92965407 1.000 0.946 ! cellular response to insulin stimulus GO:0032869 192 191 3.000 0.49243996 0.9476752 0.74323279 1.000 0.946 ! negative regulation of growth GO:0045926 191 191 3.000 0.49243996 0.9468714 0.74323279 1.000 0.946 ! epithelial to mesenchymal transition GO:0001837 49 49 1.000 0.49430066 0.94964372 1.000 1.000 0.872 ! ATP biosynthetic process GO:0006754 50 49 1.000 0.49430066 0.94883962 0.49430066 1.000 0.780 ! regulation of chemokine production GO:0032642 49 49 1.000 0.49430066 0.94803688 1.000 1.000 0.882 ! mechanoreceptor differentiation GO:0042490 49 49 1.000 0.49430066 0.9472355 1.000 1.000 0.837 ! positive regulation of JNK cascade GO:0046330 49 49 1.000 0.49430066 0.94643547 0.49430066 1.000 0.846 ! oligodendrocyte differentiation GO:0048709 51 49 1.000 0.49430066 0.94563679 0.49430066 1.000 0.864 ! sensory perception of taste GO:0050909 49 49 1.000 0.49430066 0.94483945 0.49430066 1.000 0.163 ! cellular response to hydrogen peroxide GO:0070301 49 49 1.000 0.49430066 0.94404346 0.49430066 1.000 0.849 ! cellular response to amine stimulus GO:0071418 52 49 1.000 0.49430066 0.94324881 1.000 1.000 0.819 ! regulation of neural precursor cell proliferation GO:2000177 49 49 1.000 0.49430066 0.9424555 1.000 1.000 0.869 ! anion transport GO:0006820 120 120 2.000 0.49508265 0.94315324 0.49508265 1.000 0.946 ! stress-activated protein kinase signaling cascade GO:0031098 120 120 2.000 0.49508265 0.94236134 0.81233511 1.000 0.946 ! hippocampus development GO:0021766 51 50 1.000 0.50129829 0.95339197 0.50129829 1.000 0.849 ! head development GO:0060322 50 50 1.000 0.50129829 0.95259281 0.50129829 1.000 0.843 ! cellular response to vitamin A GO:0071299 50 50 1.000 0.50129829 0.95179499 0.50129829 1.000 0.865 GO:0071300|cellular response to retinoic acid, ! cellular response to retinoic acid GO:0071300 50 50 1.000 0.50129829 0.95179499 0.50129829 1.000 0.865 GO:0071299|cellular response to vitamin A, ! cellular response to organic nitrogen GO:0071417 53 50 1.000 0.50129829 0.95099851 1.000 1.000 0.824 ! positive regulation of canonical Wnt receptor signaling pathway GO:0090263 51 50 1.000 0.50129829 0.95020336 1.000 1.000 0.820 ! vitamin metabolic process GO:0006766 122 122 2.000 0.50383759 0.95421872 0.50383759 1.000 0.946 ! maintenance of location GO:0051235 122 122 2.000 0.50383759 0.95342221 0.50383759 1.000 0.946 ! amine catabolic process GO:0009310 125 123 2.000 0.50817827 0.96083414 0.50817827 1.000 0.946 ! activation of MAPKK activity GO:0000186 51 51 1.000 0.50819948 0.96007352 1.000 1.000 0.797 ! sister chromatid segregation GO:0000819 53 51 1.000 0.50819948 0.95927412 1.000 1.000 0.768 ! branching involved in ureteric bud morphogenesis GO:0001658 51 51 1.000 0.50819948 0.95847606 0.50819948 1.000 0.871 ! positive regulation of endothelial cell proliferation GO:0001938 51 51 1.000 0.50819948 0.95767932 0.50819948 1.000 0.854 ! positive regulation of protein polymerization GO:0032273 52 51 1.000 0.50819948 0.9568839 0.50819948 1.000 0.821 ! amino acid activation GO:0043038 51 51 1.000 0.50819948 0.95608981 1.000 1.000 0.796 GO:0043039|tRNA aminoacylation, ! tRNA aminoacylation GO:0043039 51 51 1.000 0.50819948 0.95608981 1.000 1.000 0.796 GO:0043038|amino acid activation, ! epithelial cell proliferation GO:0050673 51 51 1.000 0.50819948 0.95529703 1.000 1.000 0.854 ! regulation of morphogenesis of a branching structure GO:0060688 51 51 1.000 0.50819948 0.95450557 1.000 1.000 0.880 ! positive regulation of leukocyte chemotaxis GO:0002690 52 52 1.000 0.51500555 0.96648806 0.51500555 1.000 0.883 ! smoothened signaling pathway GO:0007224 52 52 1.000 0.51500555 0.96568865 0.51500555 1.000 0.741 ! regulation of tyrosine phosphorylation of STAT protein GO:0042509 53 52 1.000 0.51500555 0.96489056 1.000 1.000 0.876 ! ATP synthesis coupled electron transport GO:0042773 52 52 1.000 0.51500555 0.96409379 1.000 1.000 0.591 GO:0042775|mitochondrial ATP synthesis coupled electron transport, ! mitochondrial ATP synthesis coupled electron transport GO:0042775 52 52 1.000 0.51500555 0.96409379 1.000 1.000 0.591 GO:0042773|ATP synthesis coupled electron transport, ! protein localization in plasma membrane GO:0072659 53 52 1.000 0.51500555 0.96329833 0.51500555 1.000 0.821 ! positive regulation of cytokine production GO:0001819 199 198 3.000 0.51647618 0.96525267 0.93713212 1.000 0.946 ! negative regulation of secretion GO:0051048 126 125 2.000 0.51678527 0.96503476 1.000 1.000 0.946 ! immune response-activating signal transduction GO:0002757 199 199 3.000 0.51986045 0.96997831 0.51986045 1.000 0.946 ! positive regulation of peptidyl-serine phosphorylation GO:0033138 54 53 1.000 0.5217178 0.97264331 1.000 1.000 0.857 ! artery development GO:0060840 53 53 1.000 0.5217178 0.97184409 1.000 1.000 0.885 ! apoptotic signaling pathway GO:0097190 53 53 1.000 0.5217178 0.97104619 0.5217178 1.000 0.791 ! G2/M transition of mitotic cell cycle GO:0000086 127 127 2.000 0.5252922 0.97689697 0.82984499 1.000 0.798 ! protein-DNA complex assembly GO:0065004 127 127 2.000 0.5252922 0.97609624 0.82984499 1.000 0.462 ! protein lipidation GO:0006497 54 54 1.000 0.52833753 0.98095102 0.52833753 1.000 0.641 ! nucleus organization GO:0006997 54 54 1.000 0.52833753 0.98014827 1.000 1.000 0.812 ! positive regulation of stress-activated MAPK cascade GO:0032874 54 54 1.000 0.52833753 0.97934684 0.52833753 1.000 0.846 ! positive regulation of JAK-STAT cascade GO:0046427 55 54 1.000 0.52833753 0.97854672 1.000 1.000 0.876 ! digestive tract morphogenesis GO:0048546 54 54 1.000 0.52833753 0.97774791 1.000 1.000 0.888 ! protein polymerization GO:0051258 55 55 1.000 0.53486601 0.98902222 0.53486601 1.000 0.536 ! positive regulation of stress-activated protein kinase signaling cascade GO:0070304 55 55 1.000 0.53486601 0.98821617 0.53486601 1.000 0.850 ! negative regulation of adenylate cyclase activity GO:0007194 56 56 1.000 0.54130448 0.99929744 1.000 1.000 0.835 ! O-glycan processing GO:0016266 57 56 1.000 0.54130448 0.99848434 0.54130448 1.000 0.0881 ! chondroitin sulfate metabolic process GO:0030204 56 56 1.000 0.54130448 0.99767257 0.54130448 1.000 0.759 ! cholesterol homeostasis GO:0042632 56 56 1.000 0.54130448 0.99686211 0.54130448 1.000 0.867 ! cellular response to mechanical stimulus GO:0071260 56 56 1.000 0.54130448 0.99605297 1.000 1.000 0.854 ! stem cell differentiation GO:0048863 132 132 2.000 0.54611546 1.000 0.84134641 1.000 0.946 ! mesoderm formation GO:0001707 57 57 1.000 0.54765419 1.000 1.000 1.000 0.873 ! terpenoid metabolic process GO:0006721 57 57 1.000 0.54765419 1.000 0.54765419 1.000 0.840 ! negative regulation of cyclase activity GO:0031280 57 57 1.000 0.54765419 1.000 1.000 1.000 0.837 ! cell redox homeostasis GO:0045454 57 57 1.000 0.54765419 1.000 0.54765419 1.000 0.480 ! sterol homeostasis GO:0055092 57 57 1.000 0.54765419 1.000 0.54765419 1.000 0.866 ! glucose catabolic process GO:0006007 58 58 1.000 0.55391634 1.000 0.55391634 1.000 0.837 ! vacuole organization GO:0007033 59 58 1.000 0.55391634 1.000 0.55391634 1.000 0.748 ! regulation of autophagy GO:0010506 58 58 1.000 0.55391634 1.000 0.55391634 1.000 0.763 ! sphingolipid biosynthetic process GO:0030148 58 58 1.000 0.55391634 1.000 0.55391634 1.000 0.752 ! regulation of alpha-beta T cell activation GO:0046634 58 58 1.000 0.55391634 1.000 1.000 1.000 0.887 ! chondroitin sulfate proteoglycan metabolic process GO:0050654 58 58 1.000 0.55391634 1.000 0.55391634 1.000 0.764 ! positive regulation of muscle cell differentiation GO:0051149 58 58 1.000 0.55391634 1.000 0.55391634 1.000 0.844 ! negative regulation of lyase activity GO:0051350 58 58 1.000 0.55391634 1.000 1.000 1.000 0.839 ! ureteric bud morphogenesis GO:0060675 58 58 1.000 0.55391634 1.000 0.55391634 1.000 0.879 ! cellular response to vitamin GO:0071295 58 58 1.000 0.55391634 1.000 0.55391634 1.000 0.877 ! positive regulation of protein ubiquitination GO:0031398 134 134 2.000 0.5542651 1.000 1.000 1.000 0.946 ! germ cell development GO:0007281 135 135 2.000 0.55830111 1.000 0.8478721 1.000 0.946 ! regulation of cell-matrix adhesion GO:0001952 59 59 1.000 0.56009216 1.000 1.000 1.000 0.875 ! lipoprotein biosynthetic process GO:0042158 59 59 1.000 0.56009216 1.000 0.56009216 1.000 0.707 ! negative regulation of intracellular protein transport GO:0090317 59 59 1.000 0.56009216 1.000 0.56009216 1.000 0.860 ! regulation of leukocyte chemotaxis GO:0002688 60 60 1.000 0.56618281 1.000 0.56618281 1.000 0.886 ! ceramide metabolic process GO:0006672 60 60 1.000 0.56618281 1.000 0.56618281 1.000 0.808 ! sensory perception of smell GO:0007608 60 60 1.000 0.56618281 1.000 1.000 1.000 0.0200 ! purine ribonucleoside triphosphate biosynthetic process GO:0009206 61 60 1.000 0.56618281 1.000 0.56618281 1.000 0.820 ! negative regulation of cAMP biosynthetic process GO:0030818 60 60 1.000 0.56618281 1.000 1.000 1.000 0.847 ! membrane lipid biosynthetic process GO:0046467 60 60 1.000 0.56618281 1.000 0.56618281 1.000 0.745 ! positive regulation of calcium ion transport GO:0051928 60 60 1.000 0.56618281 1.000 1.000 1.000 0.879 ! kidney epithelium development GO:0072073 60 60 1.000 0.56618281 1.000 0.56618281 1.000 0.890 ! chromosome segregation GO:0007059 141 137 2.000 0.56629519 1.000 0.85207334 1.000 0.946 ! mitotic cell cycle checkpoint GO:0007093 137 137 2.000 0.56629519 1.000 1.000 1.000 0.946 ! neural tube development GO:0021915 137 137 2.000 0.56629519 1.000 0.56629519 1.000 0.946 ! negative regulation of cell growth GO:0030308 137 137 2.000 0.56629519 1.000 0.56629519 1.000 0.946 ! negative regulation of cytokine production GO:0001818 139 138 2.000 0.57025315 1.000 0.85413042 1.000 0.946 ! regulation of organ morphogenesis GO:2000027 138 138 2.000 0.57025315 1.000 1.000 1.000 0.946 ! purine nucleoside triphosphate biosynthetic process GO:0009145 62 61 1.000 0.57218947 1.000 0.57218947 1.000 0.825 ! protein deubiquitination GO:0016579 61 61 1.000 0.57218947 1.000 0.57218947 1.000 0.581 ! establishment of cell polarity GO:0030010 62 61 1.000 0.57218947 1.000 1.000 1.000 0.838 ! B cell differentiation GO:0030183 61 61 1.000 0.57218947 1.000 1.000 1.000 0.851 ! negative regulation of cyclic nucleotide biosynthetic process GO:0030803 61 61 1.000 0.57218947 1.000 1.000 1.000 0.849 ! negative regulation of cAMP metabolic process GO:0030815 61 61 1.000 0.57218947 1.000 1.000 1.000 0.848 ! mesoderm morphogenesis GO:0048332 61 61 1.000 0.57218947 1.000 1.000 1.000 0.877 ! homophilic cell adhesion GO:0007156 140 139 2.000 0.57418502 1.000 0.57418502 1.000 0.000702 ! blastocyst development GO:0001824 62 62 1.000 0.5781133 1.000 0.5781133 1.000 0.801 ! acute inflammatory response GO:0002526 62 62 1.000 0.5781133 1.000 1.000 1.000 0.802 ! oxidative phosphorylation GO:0006119 62 62 1.000 0.5781133 1.000 1.000 1.000 0.690 ! fatty acid oxidation GO:0019395 62 62 1.000 0.5781133 1.000 0.5781133 1.000 0.844 ! negative regulation of cyclic nucleotide metabolic process GO:0030800 62 62 1.000 0.5781133 1.000 1.000 1.000 0.849 ! regulation of epidermal growth factor receptor signaling pathway GO:0042058 62 62 1.000 0.5781133 1.000 0.5781133 1.000 0.825 ! response to interleukin-1 GO:0070555 62 62 1.000 0.5781133 1.000 1.000 1.000 0.883 ! negative regulation of nucleotide biosynthetic process GO:0030809 63 63 1.000 0.58395542 1.000 1.000 1.000 0.854 ! lipid oxidation GO:0034440 63 63 1.000 0.58395542 1.000 0.58395542 1.000 0.846 ! regulation of protein complex disassembly GO:0043244 63 63 1.000 0.58395542 1.000 1.000 1.000 0.826 ! protein heterooligomerization GO:0051291 63 63 1.000 0.58395542 1.000 0.58395542 1.000 0.842 ! protein-DNA complex subunit organization GO:0071824 142 142 2.000 0.58582364 1.000 0.86207774 1.000 0.596 ! hexose transport GO:0008645 64 64 1.000 0.58971697 1.000 1.000 1.000 0.761 GO:0015758|glucose transport, ! negative regulation of phosphatase activity GO:0010923 64 64 1.000 0.58971697 1.000 0.58971697 1.000 0.242 ! glucose transport GO:0015758 64 64 1.000 0.58971697 1.000 1.000 1.000 0.761 GO:0008645|hexose transport, ! transcription elongation from RNA polymerase II promoter GO:0006368 69 65 1.000 0.59539905 1.000 0.59539905 1.000 0.648 ! regulation of receptor activity GO:0010469 65 65 1.000 0.59539905 1.000 0.59539905 1.000 0.868 ! monosaccharide transport GO:0015749 65 65 1.000 0.59539905 1.000 1.000 1.000 0.764 ! positive regulation of Rho GTPase activity GO:0032321 65 65 1.000 0.59539905 1.000 0.59539905 1.000 0.815 ! positive regulation of neuron differentiation GO:0045666 65 65 1.000 0.59539905 1.000 1.000 1.000 0.852 ! interferon-gamma-mediated signaling pathway GO:0060333 65 65 1.000 0.59539905 1.000 0.59539905 1.000 0.830 ! type I interferon-mediated signaling pathway GO:0060337 65 65 1.000 0.59539905 1.000 0.59539905 1.000 0.690 GO:0071357|cellular response to type I interferon, ! cellular response to type I interferon GO:0071357 65 65 1.000 0.59539905 1.000 0.59539905 1.000 0.690 GO:0060337|type I interferon-mediated signaling pathway, ! meiosis GO:0007126 148 145 2.000 0.59722637 1.000 0.59722637 1.000 0.946 GO:0051327|M phase of meiotic cell cycle, ! glycosaminoglycan metabolic process GO:0030203 145 145 2.000 0.59722637 1.000 0.59722637 1.000 0.946 ! M phase of meiotic cell cycle GO:0051327 148 145 2.000 0.59722637 1.000 0.59722637 1.000 0.946 GO:0007126|meiosis, ! cellular response to nutrient levels GO:0031669 147 146 2.000 0.6009748 1.000 0.6009748 1.000 0.946 ! DNA modification GO:0006304 66 66 1.000 0.60100276 1.000 0.60100276 1.000 0.857 ! nucleobase metabolic process GO:0009112 66 66 1.000 0.60100276 1.000 0.60100276 1.000 0.871 ! ribonucleoside triphosphate biosynthetic process GO:0009201 67 66 1.000 0.60100276 1.000 0.60100276 1.000 0.839 ! response to type I interferon GO:0034340 66 66 1.000 0.60100276 1.000 0.60100276 1.000 0.693 ! odontogenesis of dentin-containing tooth GO:0042475 66 66 1.000 0.60100276 1.000 0.60100276 1.000 0.867 ! negative regulation of nucleotide metabolic process GO:0045980 66 66 1.000 0.60100276 1.000 1.000 1.000 0.858 ! sphingoid metabolic process GO:0046519 66 66 1.000 0.60100276 1.000 0.60100276 1.000 0.816 ! regulation of dendrite development GO:0050773 67 66 1.000 0.60100276 1.000 0.60100276 1.000 0.863 ! regulation of coagulation GO:0050818 66 66 1.000 0.60100276 1.000 0.60100276 1.000 0.874 ! regulation of oxidoreductase activity GO:0051341 66 66 1.000 0.60100276 1.000 1.000 1.000 0.880 ! positive regulation of protein kinase B signaling cascade GO:0051897 66 66 1.000 0.60100276 1.000 1.000 1.000 0.878 ! negative regulation of reproductive process GO:2000242 66 66 1.000 0.60100276 1.000 0.60100276 1.000 0.866 ! regulation of stress-activated MAPK cascade GO:0032872 147 147 2.000 0.60469701 1.000 0.60469701 1.000 0.946 ! neural tube closure GO:0001843 67 67 1.000 0.60652916 1.000 0.60652916 1.000 0.853 ! negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 67 67 1.000 0.60652916 1.000 0.60652916 1.000 0.810 ! TRIF-dependent toll-like receptor signaling pathway GO:0035666 67 67 1.000 0.60652916 1.000 0.60652916 1.000 0.859 ! ovum-producing ovary development GO:0061039 67 67 1.000 0.60652916 1.000 0.60652916 1.000 0.868 ! myeloid cell differentiation GO:0030099 148 148 2.000 0.60839298 1.000 0.60839298 1.000 0.946 ! regulation of lymphocyte proliferation GO:0050670 148 148 2.000 0.60839298 1.000 1.000 1.000 0.946 ! meiotic cell cycle GO:0051321 151 148 2.000 0.60839298 1.000 0.60839298 1.000 0.946 ! regulation of stress-activated protein kinase signaling cascade GO:0070302 148 148 2.000 0.60839298 1.000 0.60839298 1.000 0.946 ! microtubule-based transport GO:0010970 68 68 1.000 0.61197932 1.000 0.61197932 1.000 0.828 ! cellular response to nutrient GO:0031670 68 68 1.000 0.61197932 1.000 0.61197932 1.000 0.883 ! regulation of tumor necrosis factor production GO:0032680 68 68 1.000 0.61197932 1.000 1.000 1.000 0.889 ! toll-like receptor 1 signaling pathway GO:0034130 68 68 1.000 0.61197932 1.000 0.61197932 1.000 0.860 ! tube closure GO:0060606 68 68 1.000 0.61197932 1.000 0.61197932 1.000 0.856 ! monocarboxylic acid catabolic process GO:0072329 68 68 1.000 0.61197932 1.000 0.61197932 1.000 0.855 ! xenobiotic metabolic process GO:0006805 149 149 2.000 0.61206274 1.000 0.87496172 1.000 0.946 ! regulation of mononuclear cell proliferation GO:0032944 149 149 2.000 0.61206274 1.000 1.000 1.000 0.946 ! cellular response to xenobiotic stimulus GO:0071466 150 150 2.000 0.6157063 1.000 0.87670169 1.000 0.946 ! MyD88-independent toll-like receptor signaling pathway GO:0002756 69 69 1.000 0.61735429 1.000 0.61735429 1.000 0.860 ! peptidyl-serine phosphorylation GO:0018105 69 69 1.000 0.61735429 1.000 0.61735429 1.000 0.859 ! regulation of interferon-gamma production GO:0032649 70 69 1.000 0.61735429 1.000 1.000 1.000 0.889 ! regulation of interleukin-6 production GO:0032675 69 69 1.000 0.61735429 1.000 1.000 1.000 0.889 ! toll-like receptor 2 signaling pathway GO:0034134 69 69 1.000 0.61735429 1.000 0.61735429 1.000 0.862 ! toll-like receptor 3 signaling pathway GO:0034138 69 69 1.000 0.61735429 1.000 0.61735429 1.000 0.862 ! cellular response to radiation GO:0071478 70 69 1.000 0.61735429 1.000 1.000 1.000 0.867 ! nucleoside triphosphate biosynthetic process GO:0009142 71 70 1.000 0.6226551 1.000 0.6226551 1.000 0.851 ! glucose metabolic process GO:0006006 152 152 2.000 0.6229149 1.000 0.6229149 1.000 0.946 ! response to xenobiotic stimulus GO:0009410 152 152 2.000 0.6229149 1.000 0.88010961 1.000 0.946 ! myeloid leukocyte differentiation GO:0002573 71 71 1.000 0.62788278 1.000 0.62788278 1.000 0.873 ! negative regulation of T cell activation GO:0050868 72 71 1.000 0.62788278 1.000 1.000 1.000 0.874 ! aminoglycan metabolic process GO:0006022 154 154 2.000 0.63001902 1.000 0.63001902 1.000 0.946 ! regulation of leukocyte proliferation GO:0070663 154 154 2.000 0.63001902 1.000 1.000 1.000 0.946 ! primary neural tube formation GO:0014020 72 72 1.000 0.63303832 1.000 0.63303832 1.000 0.861 ! positive regulation of Wnt receptor signaling pathway GO:0030177 73 72 1.000 0.63303832 1.000 1.000 1.000 0.863 ! positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051437 72 72 1.000 0.63303832 1.000 1.000 1.000 0.833 ! regulation of endothelial cell proliferation GO:0001936 73 73 1.000 0.63812271 1.000 0.63812271 1.000 0.878 ! MyD88-dependent toll-like receptor signaling pathway GO:0002755 73 73 1.000 0.63812271 1.000 0.63812271 1.000 0.861 ! protein O-linked glycosylation GO:0006493 74 73 1.000 0.63812271 1.000 0.63812271 1.000 0.352 ! hexose catabolic process GO:0019320 73 73 1.000 0.63812271 1.000 0.63812271 1.000 0.855 ! spinal cord development GO:0021510 74 73 1.000 0.63812271 1.000 1.000 1.000 0.853 ! cytoskeleton-dependent intracellular transport GO:0030705 73 73 1.000 0.63812271 1.000 0.63812271 1.000 0.825 ! regulation of JAK-STAT cascade GO:0046425 74 73 1.000 0.63812271 1.000 1.000 1.000 0.882 ! post-Golgi vesicle-mediated transport GO:0006892 74 74 1.000 0.64313694 1.000 0.64313694 1.000 0.680 ! protein modification by small protein removal GO:0070646 74 74 1.000 0.64313694 1.000 0.64313694 1.000 0.613 ! regulation of proteolysis GO:0030162 159 158 2.000 0.64391501 1.000 0.88978067 1.000 0.946 ! cellular membrane fusion GO:0006944 77 75 1.000 0.64808198 1.000 0.64808198 1.000 0.713 ! cell recognition GO:0008037 75 75 1.000 0.64808198 1.000 0.64808198 1.000 0.831 ! regulation of cell size GO:0008361 77 75 1.000 0.64808198 1.000 0.64808198 1.000 0.869 ! cellular response to starvation GO:0009267 76 75 1.000 0.64808198 1.000 0.64808198 1.000 0.843 ! positive regulation of cell cycle process GO:0090068 161 160 2.000 0.65070765 1.000 0.65070765 1.000 0.946 ! inorganic anion transport GO:0015698 76 76 1.000 0.65295876 1.000 0.65295876 1.000 0.732 ! metencephalon development GO:0022037 77 76 1.000 0.65295876 1.000 0.65295876 1.000 0.874 ! anatomical structure homeostasis GO:0060249 162 162 2.000 0.65739731 1.000 0.8957923 1.000 0.946 ! positive regulation of chemotaxis GO:0050921 77 77 1.000 0.65776823 1.000 0.65776823 1.000 0.889 ! plasma membrane organization GO:0007009 80 78 1.000 0.66251131 1.000 0.66251131 1.000 0.852 ! spermatid development GO:0007286 78 78 1.000 0.66251131 1.000 0.66251131 1.000 0.734 ! mRNA 3'-end processing GO:0031124 79 78 1.000 0.66251131 1.000 0.66251131 1.000 0.674 ! positive regulation of binding GO:0051099 78 78 1.000 0.66251131 1.000 1.000 1.000 0.879 ! regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051439 78 78 1.000 0.66251131 1.000 1.000 1.000 0.844 ! epithelial cell development GO:0002064 79 79 1.000 0.66718892 1.000 1.000 1.000 0.886 ! isoprenoid metabolic process GO:0006720 79 79 1.000 0.66718892 1.000 0.66718892 1.000 0.869 ! meiosis I GO:0007127 79 79 1.000 0.66718892 1.000 0.66718892 1.000 0.837 ! vesicle localization GO:0051648 79 79 1.000 0.66718892 1.000 0.66718892 1.000 0.859 ! membrane fusion GO:0061025 81 79 1.000 0.66718892 1.000 0.66718892 1.000 0.746 ! nucleotide-excision repair GO:0006289 80 80 1.000 0.67180196 1.000 0.67180196 1.000 0.946 ! Toll signaling pathway GO:0008063 80 80 1.000 0.67180196 1.000 0.67180196 1.000 0.869 ! regulation of exocytosis GO:0017157 80 80 1.000 0.67180196 1.000 1.000 1.000 0.848 ! anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031145 80 80 1.000 0.67180196 1.000 1.000 1.000 0.946 ! negative regulation of epithelial cell proliferation GO:0050680 80 80 1.000 0.67180196 1.000 0.67180196 1.000 0.879 ! G1/S transition of mitotic cell cycle GO:0000082 167 167 2.000 0.67367446 1.000 0.90284961 1.000 0.946 ! peptidyl-serine modification GO:0018209 81 81 1.000 0.67635131 1.000 0.67635131 1.000 0.858 ! peptide metabolic process GO:0006518 82 82 1.000 0.68083786 1.000 1.000 1.000 0.789 ! toll-like receptor 4 signaling pathway GO:0034142 82 82 1.000 0.68083786 1.000 0.68083786 1.000 0.870 ! positive regulation of ubiquitin-protein ligase activity GO:0051443 82 82 1.000 0.68083786 1.000 1.000 1.000 0.946 ! transcription termination, DNA-dependent GO:0006353 83 83 1.000 0.68526245 1.000 0.68526245 1.000 0.666 ! determination of left/right symmetry GO:0007368 83 83 1.000 0.68526245 1.000 0.68526245 1.000 0.880 ! monosaccharide catabolic process GO:0046365 83 83 1.000 0.68526245 1.000 0.68526245 1.000 0.865 ! spermatid differentiation GO:0048515 83 83 1.000 0.68526245 1.000 0.68526245 1.000 0.749 ! regulation of reproductive process GO:2000241 175 171 2.000 0.68624146 1.000 0.90815106 1.000 0.946 ! cell activation involved in immune response GO:0002263 84 84 1.000 0.68962596 1.000 0.68962596 1.000 0.889 GO:0002366|leukocyte activation involved in immune response, ! leukocyte activation involved in immune response GO:0002366 84 84 1.000 0.68962596 1.000 0.68962596 1.000 0.889 GO:0002263|cell activation involved in immune response, ! purine ribonucleotide biosynthetic process GO:0009152 85 84 1.000 0.68962596 1.000 0.68962596 1.000 0.869 ! viral genome expression GO:0019080 84 84 1.000 0.68962596 1.000 0.68962596 1.000 0.538 GO:0019083|viral transcription, ! viral transcription GO:0019083 84 84 1.000 0.68962596 1.000 0.68962596 1.000 0.538 GO:0019080|viral genome expression, ! response to tumor necrosis factor GO:0034612 85 84 1.000 0.68962596 1.000 1.000 1.000 0.875 ! positive regulation of protein secretion GO:0050714 84 84 1.000 0.68962596 1.000 1.000 1.000 0.885 ! cellular response to interferon-gamma GO:0071346 84 84 1.000 0.68962596 1.000 0.68962596 1.000 0.946 ! mitotic prometaphase GO:0000236 86 85 1.000 0.69392921 1.000 1.000 1.000 0.743 ! polysaccharide catabolic process GO:0000272 85 85 1.000 0.69392921 1.000 0.69392921 1.000 0.946 ! neural tube formation GO:0001841 85 85 1.000 0.69392921 1.000 0.69392921 1.000 0.870 ! transcription elongation, DNA-dependent GO:0006354 89 85 1.000 0.69392921 1.000 0.69392921 1.000 0.695 ! translational termination GO:0006415 85 85 1.000 0.69392921 1.000 0.69392921 1.000 0.515 ! JNK cascade GO:0007254 85 85 1.000 0.69392921 1.000 1.000 1.000 0.946 ! regulation of cyclin-dependent protein kinase activity GO:0000079 86 86 1.000 0.69817303 1.000 1.000 1.000 0.723 ! protein processing GO:0016485 86 86 1.000 0.69817303 1.000 0.69817303 1.000 0.946 ! keratinocyte differentiation GO:0030216 86 86 1.000 0.69817303 1.000 0.69817303 1.000 0.534 ! positive regulation of ligase activity GO:0051351 86 86 1.000 0.69817303 1.000 1.000 1.000 0.946 ! lipid homeostasis GO:0055088 87 87 1.000 0.70235825 1.000 0.70235825 1.000 0.886 ! cellular response to lipopolysaccharide GO:0071222 87 87 1.000 0.70235825 1.000 0.70235825 1.000 0.890 ! cytokinesis GO:0000910 88 88 1.000 0.70648566 1.000 0.70648566 1.000 0.794 ! regulation of actin filament polymerization GO:0030833 89 88 1.000 0.70648566 1.000 0.70648566 1.000 0.946 ! positive regulation of behavior GO:0048520 88 88 1.000 0.70648566 1.000 0.70648566 1.000 0.891 ! iron ion homeostasis GO:0055072 88 88 1.000 0.70648566 1.000 0.70648566 1.000 0.768 ! regulation of protein ubiquitination GO:0031396 179 179 2.000 0.71018691 1.000 1.000 1.000 0.946 ! determination of bilateral symmetry GO:0009855 89 89 1.000 0.71055607 1.000 0.71055607 1.000 0.884 ! regulation of cellular component size GO:0032535 183 180 2.000 0.71307058 1.000 0.71307058 1.000 0.946 ! proteasomal ubiquitin-dependent protein catabolic process GO:0043161 180 180 2.000 0.71307058 1.000 0.91904933 1.000 0.946 ! specification of symmetry GO:0009799 90 90 1.000 0.71457026 1.000 0.71457026 1.000 0.885 ! stem cell maintenance GO:0019827 90 90 1.000 0.71457026 1.000 1.000 1.000 0.946 ! cytokine production GO:0001816 91 91 1.000 0.71852899 1.000 1.000 1.000 0.884 ! regulation of cytokine biosynthetic process GO:0042035 91 91 1.000 0.71852899 1.000 1.000 1.000 0.887 ! positive regulation of ion transport GO:0043270 91 91 1.000 0.71852899 1.000 1.000 1.000 0.887 ! regulation of response to cytokine stimulus GO:0060759 91 91 1.000 0.71852899 1.000 1.000 1.000 0.946 ! toll-like receptor signaling pathway GO:0002224 92 92 1.000 0.72243304 1.000 0.72243304 1.000 0.946 ! potassium ion transport GO:0006813 92 92 1.000 0.72243304 1.000 0.72243304 1.000 0.684 ! cell growth GO:0016049 92 92 1.000 0.72243304 1.000 0.72243304 1.000 0.946 ! protein N-linked glycosylation via asparagine GO:0018279 92 92 1.000 0.72243304 1.000 0.72243304 1.000 0.768 ! antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 92 92 1.000 0.72243304 1.000 0.72243304 1.000 0.741 ! RNA 3'-end processing GO:0031123 94 92 1.000 0.72243304 1.000 0.72243304 1.000 0.745 ! cellular response to molecule of bacterial origin GO:0071219 92 92 1.000 0.72243304 1.000 0.72243304 1.000 0.890 ! proteasomal protein catabolic process GO:0010498 184 184 2.000 0.72436651 1.000 0.92346995 1.000 0.946 ! peptidyl-asparagine modification GO:0018196 93 93 1.000 0.72628316 1.000 0.72628316 1.000 0.774 ! lipoprotein metabolic process GO:0042157 93 93 1.000 0.72628316 1.000 0.72628316 1.000 0.946 ! carbohydrate catabolic process GO:0016052 185 185 2.000 0.72713137 1.000 0.72713137 1.000 0.946 ! ion transmembrane transport GO:0034220 186 185 2.000 0.72713137 1.000 0.72713137 1.000 0.946 ! antigen processing and presentation of peptide antigen via MHC class II GO:0002495 94 94 1.000 0.73008009 1.000 0.73008009 1.000 0.741 GO:0002504|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, ! antigen processing and presentation of peptide or polysaccharide antigen via MHC class II GO:0002504 94 94 1.000 0.73008009 1.000 0.73008009 1.000 0.741 GO:0002495|antigen processing and presentation of peptide antigen via MHC class II, ! positive regulation of protein complex assembly GO:0031334 95 94 1.000 0.73008009 1.000 0.73008009 1.000 0.946 ! one-carbon metabolic process GO:0006730 189 187 2.000 0.73259094 1.000 0.73259094 1.000 0.946 ! positive regulation of MAP kinase activity GO:0043406 188 187 2.000 0.73259094 1.000 0.73259094 1.000 0.946 ! stem cell development GO:0048864 95 95 1.000 0.73382455 1.000 1.000 1.000 0.946 ! detection of stimulus involved in sensory perception GO:0050906 95 95 1.000 0.73382455 1.000 1.000 1.000 0.593 ! maintenance of location in cell GO:0051651 95 95 1.000 0.73382455 1.000 0.73382455 1.000 0.946 ! ER-nucleus signaling pathway GO:0006984 96 96 1.000 0.73751728 1.000 0.73751728 1.000 0.946 ! pallium development GO:0021543 97 96 1.000 0.73751728 1.000 0.73751728 1.000 0.887 ! regulation of ubiquitin-protein ligase activity GO:0051438 96 96 1.000 0.73751728 1.000 1.000 1.000 0.946 ! negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway GO:0090101 96 96 1.000 0.73751728 1.000 0.73751728 1.000 0.946 ! amino acid transport GO:0006865 97 97 1.000 0.74115898 1.000 0.74115898 1.000 0.946 ! negative regulation of lymphocyte activation GO:0051250 98 97 1.000 0.74115898 1.000 1.000 1.000 0.946 ! cell-matrix adhesion GO:0007160 99 98 1.000 0.74475036 1.000 0.74475036 1.000 0.741 ! male gonad development GO:0008584 98 98 1.000 0.74475036 1.000 1.000 1.000 0.946 ! maintenance of protein location GO:0045185 98 98 1.000 0.74475036 1.000 0.74475036 1.000 0.946 ! response to starvation GO:0042594 100 99 1.000 0.74829211 1.000 0.74829211 1.000 0.946 ! cellular protein complex disassembly GO:0043624 99 99 1.000 0.74829211 1.000 0.74829211 1.000 0.644 ! protein maturation GO:0051604 99 99 1.000 0.74829211 1.000 0.74829211 1.000 0.946 ! protein N-linked glycosylation GO:0006487 100 100 1.000 0.75178491 1.000 0.75178491 1.000 0.784 ! regulation of actin polymerization or depolymerization GO:0008064 101 100 1.000 0.75178491 1.000 0.75178491 1.000 0.946 ! ribonucleotide biosynthetic process GO:0009260 101 100 1.000 0.75178491 1.000 0.75178491 1.000 0.946 ! regulation of ligase activity GO:0051340 100 100 1.000 0.75178491 1.000 1.000 1.000 0.946 ! hexose metabolic process GO:0019318 195 195 2.000 0.75351141 1.000 0.75351141 1.000 0.946 ! respiratory electron transport chain GO:0022904 101 101 1.000 0.75522944 1.000 1.000 1.000 0.754 ! regulation of actin filament length GO:0030832 102 101 1.000 0.75522944 1.000 0.75522944 1.000 0.946 ! protein complex disassembly GO:0043241 101 101 1.000 0.75522944 1.000 0.75522944 1.000 0.661 ! RNA splicing, via transesterification reactions with bulged adenosine as nucleophile GO:0000377 196 196 2.000 0.75602524 1.000 0.75602524 1.000 0.609 GO:0000398|nuclear mRNA splicing, via spliceosome, ! nuclear mRNA splicing, via spliceosome GO:0000398 196 196 2.000 0.75602524 1.000 0.75602524 1.000 0.609 GO:0000377|RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, ! establishment or maintenance of cell polarity GO:0007163 103 102 1.000 0.75862636 1.000 1.000 1.000 0.946 ! ribonucleoprotein complex assembly GO:0022618 102 102 1.000 0.75862636 1.000 0.75862636 1.000 0.787 ! translational elongation GO:0006414 103 103 1.000 0.76197632 1.000 0.76197632 1.000 0.583 ! positive regulation of cellular catabolic process GO:0031331 103 103 1.000 0.76197632 1.000 0.76197632 1.000 0.946 ! regulation of chemotaxis GO:0050920 103 103 1.000 0.76197632 1.000 0.76197632 1.000 0.891 ! B cell activation GO:0042113 104 104 1.000 0.76527997 1.000 1.000 1.000 0.946 ! protein acetylation GO:0006473 105 105 1.000 0.76853796 1.000 0.76853796 1.000 0.946 ! SRP-dependent cotranslational protein targeting to membrane GO:0006614 105 105 1.000 0.76853796 1.000 0.76853796 1.000 0.610 ! positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 106 105 1.000 0.76853796 1.000 1.000 1.000 0.891 ! regulation of cell shape GO:0008360 107 106 1.000 0.7717509 1.000 1.000 1.000 0.778 ! response to endoplasmic reticulum stress GO:0034976 106 106 1.000 0.7717509 1.000 0.7717509 1.000 0.946 ! nucleosome assembly GO:0006334 107 107 1.000 0.77491943 1.000 0.77491943 1.000 0.140 ! cotranslational protein targeting to membrane GO:0006613 107 107 1.000 0.77491943 1.000 0.77491943 1.000 0.613 ! protein targeting to ER GO:0045047 107 107 1.000 0.77491943 1.000 0.77491943 1.000 0.614 ! ribonucleoprotein complex subunit organization GO:0071826 107 107 1.000 0.77491943 1.000 0.77491943 1.000 0.798 ! carbohydrate homeostasis GO:0033500 108 108 1.000 0.77804414 1.000 0.77804414 1.000 0.946 GO:0042593|glucose homeostasis, ! glucose homeostasis GO:0042593 108 108 1.000 0.77804414 1.000 0.77804414 1.000 0.946 GO:0033500|carbohydrate homeostasis, ! macromolecule methylation GO:0043414 109 108 1.000 0.77804414 1.000 0.77804414 1.000 0.946 ! alcohol catabolic process GO:0046164 108 108 1.000 0.77804414 1.000 0.77804414 1.000 0.946 ! establishment of protein localization in endoplasmic reticulum GO:0072599 108 108 1.000 0.77804414 1.000 0.77804414 1.000 0.627 ! cellular carbohydrate biosynthetic process GO:0034637 109 109 1.000 0.78112565 1.000 0.78112565 1.000 0.946 ! negative regulation of leukocyte activation GO:0002695 112 111 1.000 0.78716141 1.000 1.000 1.000 0.946 ! embryonic limb morphogenesis GO:0030326 113 113 1.000 0.79303139 1.000 0.79303139 1.000 0.946 GO:0035113|embryonic appendage morphogenesis, ! embryonic appendage morphogenesis GO:0035113 113 113 1.000 0.79303139 1.000 0.79303139 1.000 0.946 GO:0030326|embryonic limb morphogenesis, ! regulation of viral reproduction GO:0050792 117 113 1.000 0.79303139 1.000 0.79303139 1.000 0.946 ! Notch signaling pathway GO:0007219 118 114 1.000 0.79590563 1.000 1.000 1.000 0.946 ! development of primary male sexual characteristics GO:0046546 115 115 1.000 0.79874012 1.000 1.000 1.000 0.946 ! chromatin assembly GO:0031497 118 117 1.000 0.804292 1.000 0.804292 1.000 0.330 ! nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 118 118 1.000 0.80701048 1.000 0.80701048 1.000 0.599 ! sphingolipid metabolic process GO:0006665 118 118 1.000 0.80701048 1.000 0.80701048 1.000 0.946 ! S phase GO:0051320 119 119 1.000 0.80969134 1.000 0.80969134 1.000 0.946 ! methylation GO:0032259 122 120 1.000 0.81233511 1.000 0.81233511 1.000 0.946 ! cellular macromolecular complex disassembly GO:0034623 120 120 1.000 0.81233511 1.000 0.81233511 1.000 0.739 ! ATP metabolic process GO:0046034 121 120 1.000 0.81233511 1.000 0.81233511 1.000 0.946 ! negative regulation of cell activation GO:0050866 121 120 1.000 0.81233511 1.000 1.000 1.000 0.946 ! translational initiation GO:0006413 122 121 1.000 0.8149423 1.000 0.8149423 1.000 0.603 ! protein acylation GO:0043543 121 121 1.000 0.8149423 1.000 0.8149423 1.000 0.946 ! protein localization in endoplasmic reticulum GO:0070972 121 121 1.000 0.8149423 1.000 0.8149423 1.000 0.695 ! macromolecular complex disassembly GO:0032984 122 122 1.000 0.81751341 1.000 0.81751341 1.000 0.749 ! regulation of gene expression, epigenetic GO:0040029 127 123 1.000 0.82004895 1.000 0.82004895 1.000 0.946 ! male sex differentiation GO:0046661 123 123 1.000 0.82004895 1.000 1.000 1.000 0.946 ! tRNA metabolic process GO:0006399 124 124 1.000 0.82254939 1.000 1.000 1.000 0.764 ! membrane lipid metabolic process GO:0006643 125 125 1.000 0.82501523 1.000 0.82501523 1.000 0.946 ! nucleosome organization GO:0034728 126 126 1.000 0.82744694 1.000 0.82744694 1.000 0.425 ! sensory perception of sound GO:0007605 127 127 1.000 0.82984499 1.000 0.82984499 1.000 0.946 ! regulation of peptidyl-tyrosine phosphorylation GO:0050730 128 127 1.000 0.82984499 1.000 1.000 1.000 0.946 ! activation of MAPK activity GO:0000187 128 128 1.000 0.83220985 1.000 0.83220985 1.000 0.946 ! Ras protein signal transduction GO:0007265 131 131 1.000 0.83910982 1.000 1.000 1.000 0.946 ! cell-substrate adhesion GO:0031589 132 131 1.000 0.83910982 1.000 0.83910982 1.000 0.946 ! regulation of JNK cascade GO:0046328 131 131 1.000 0.83910982 1.000 0.83910982 1.000 0.946 ! leukocyte mediated immunity GO:0002443 132 132 1.000 0.84134641 1.000 0.84134641 1.000 0.946 ! chromatin assembly or disassembly GO:0006333 136 135 1.000 0.8478721 1.000 0.8478721 1.000 0.507 ! viral infectious cycle GO:0019058 137 136 1.000 0.84998737 1.000 0.84998737 1.000 0.798 ! positive regulation of catabolic process GO:0009896 138 138 1.000 0.85413042 1.000 0.85413042 1.000 0.946 ! electron transport chain GO:0022900 141 141 1.000 0.86013229 1.000 1.000 1.000 0.748 ! defense response to bacterium GO:0042742 142 141 1.000 0.86013229 1.000 0.86013229 1.000 0.761 ! endosome transport GO:0016197 142 142 1.000 0.86207774 1.000 0.86207774 1.000 0.693 ! homeostasis of number of cells GO:0048872 148 147 1.000 0.87140808 1.000 0.87140808 1.000 0.946 ! cellular response to abiotic stimulus GO:0071214 150 148 1.000 0.8731973 1.000 1.000 1.000 0.946 ! DNA packaging GO:0006323 151 150 1.000 0.87670169 1.000 0.87670169 1.000 0.577 ! lymphocyte differentiation GO:0030098 157 157 1.000 0.88822456 1.000 1.000 1.000 0.946 ! protein targeting to membrane GO:0006612 159 158 1.000 0.88978067 1.000 0.88978067 1.000 0.946 ! antigen processing and presentation of exogenous peptide antigen GO:0002478 168 168 1.000 0.90420287 1.000 0.90420287 1.000 0.946 ! antigen processing and presentation of exogenous antigen GO:0019884 170 170 1.000 0.90685334 1.000 0.90685334 1.000 0.946 ! nuclear-transcribed mRNA catabolic process GO:0000956 176 174 1.000 0.91193716 1.000 0.91193716 1.000 0.745 ! Golgi vesicle transport GO:0048193 177 177 1.000 0.9155678 1.000 0.9155678 1.000 0.785 ! T cell activation GO:0042110 178 178 1.000 0.91674457 1.000 0.91674457 1.000 0.946 ! negative regulation of immune system process GO:0002683 182 180 1.000 0.91904933 1.000 1.000 1.000 0.946 ! mRNA catabolic process GO:0006402 188 184 1.000 0.92346995 1.000 0.92346995 1.000 0.775 ! antigen processing and presentation of peptide antigen GO:0048002 185 185 1.000 0.924537 1.000 0.924537 1.000 0.946 ! DNA conformation change GO:0071103 186 185 1.000 0.924537 1.000 0.924537 1.000 0.746 ! DNA recombination GO:0006310 188 187 1.000 0.92662687 1.000 0.92662687 1.000 0.946 ! post-translational protein modification GO:0043687 197 196 1.000 0.93534034 1.000 0.93534034 1.000 0.946 ! regulation of DNA recombination GO:0000018 41 41 0.000 1.000 1.000 1.000 1.000 0.848 ! transition metal ion transport GO:0000041 93 93 0.000 1.000 1.000 1.000 1.000 0.765 ! autophagic vacuole assembly GO:0000045 25 24 0.000 1.000 1.000 1.000 1.000 0.365 ! protein import into nucleus, translocation GO:0000060 23 23 0.000 1.000 1.000 1.000 1.000 0.701 ! DNA damage checkpoint GO:0000077 134 133 0.000 1.000 1.000 1.000 1.000 0.946 ! G1 phase of mitotic cell cycle GO:0000080 46 46 0.000 1.000 1.000 1.000 1.000 0.667 ! regulation of transcription involved in G1/S phase of mitotic cell cycle GO:0000083 23 23 0.000 1.000 1.000 1.000 1.000 0.598 ! S phase of mitotic cell cycle GO:0000084 116 116 0.000 1.000 1.000 1.000 1.000 0.946 ! protein polyubiquitination GO:0000209 165 165 0.000 1.000 1.000 1.000 1.000 0.946 ! M/G1 transition of mitotic cell cycle GO:0000216 79 79 0.000 1.000 1.000 1.000 1.000 0.791 ! spliceosome assembly GO:0000245 37 37 0.000 1.000 1.000 1.000 1.000 0.434 ! nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 55 54 0.000 1.000 1.000 1.000 1.000 0.519 ! nuclear-transcribed mRNA poly(A) tail shortening GO:0000289 26 25 0.000 1.000 1.000 1.000 1.000 0.326 ! nuclear-transcribed mRNA catabolic process, exonucleolytic GO:0000291 26 26 0.000 1.000 1.000 1.000 1.000 0.296 GO:0043928|exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay, ! spliceosomal snRNP assembly GO:0000387 31 31 0.000 1.000 1.000 1.000 1.000 0.455 ! nucleotide-excision repair, DNA damage removal GO:0000718 21 21 0.000 1.000 1.000 1.000 1.000 0.653 GO:0044349|DNA excision, ! telomere maintenance via recombination GO:0000722 27 27 0.000 1.000 1.000 1.000 1.000 0.716 ! telomere maintenance GO:0000723 58 58 0.000 1.000 1.000 1.000 1.000 0.837 ! double-strand break repair via homologous recombination GO:0000724 48 48 0.000 1.000 1.000 1.000 1.000 0.714 ! recombinational repair GO:0000725 50 49 0.000 1.000 1.000 1.000 1.000 0.717 ! patterning of blood vessels GO:0001569 34 34 0.000 1.000 1.000 1.000 1.000 0.819 ! microtubule bundle formation GO:0001578 31 31 0.000 1.000 1.000 1.000 1.000 0.602 ! morphogenesis of a polarized epithelium GO:0001738 21 21 0.000 1.000 1.000 1.000 1.000 0.757 ! organ induction GO:0001759 20 20 0.000 1.000 1.000 1.000 1.000 0.783 ! leukocyte homeostasis GO:0001776 43 43 0.000 1.000 1.000 1.000 1.000 0.856 ! mesonephros development GO:0001823 21 21 0.000 1.000 1.000 1.000 1.000 0.854 ! release of cytochrome c from mitochondria GO:0001836 25 25 0.000 1.000 1.000 1.000 1.000 0.798 ! liver development GO:0001889 78 78 0.000 1.000 1.000 1.000 1.000 0.881 ! tissue homeostasis GO:0001894 87 87 0.000 1.000 1.000 1.000 1.000 0.876 ! cell killing GO:0001906 34 34 0.000 1.000 1.000 1.000 1.000 0.660 ! regulation of leukocyte mediated cytotoxicity GO:0001910 33 33 0.000 1.000 1.000 1.000 1.000 0.856 ! positive regulation of leukocyte mediated cytotoxicity GO:0001912 26 26 0.000 1.000 1.000 1.000 1.000 0.838 ! heart looping GO:0001947 44 44 0.000 1.000 1.000 1.000 1.000 0.870 ! positive regulation of cell-matrix adhesion GO:0001954 25 25 0.000 1.000 1.000 1.000 1.000 0.815 ! endochondral ossification GO:0001958 22 22 0.000 1.000 1.000 1.000 1.000 0.708 GO:0036075|replacement ossification, ! regulation of cytokine-mediated signaling pathway GO:0001959 85 85 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of cytokine-mediated signaling pathway GO:0001960 26 26 0.000 1.000 1.000 1.000 1.000 0.812 ! blood vessel remodeling GO:0001974 34 34 0.000 1.000 1.000 1.000 1.000 0.863 ! sprouting angiogenesis GO:0002040 38 38 0.000 1.000 1.000 1.000 1.000 0.822 ! chondrocyte differentiation GO:0002062 43 43 0.000 1.000 1.000 1.000 1.000 0.852 ! somatic diversification of immune receptors GO:0002200 39 39 0.000 1.000 1.000 1.000 1.000 0.843 ! hemopoietic progenitor cell differentiation GO:0002244 30 30 0.000 1.000 1.000 1.000 1.000 0.819 ! adaptive immune response GO:0002250 133 133 0.000 1.000 1.000 1.000 1.000 0.946 ! lymphocyte homeostasis GO:0002260 40 40 0.000 1.000 1.000 1.000 1.000 0.848 ! lymphocyte activation involved in immune response GO:0002285 54 54 0.000 1.000 1.000 1.000 1.000 0.879 ! T cell activation involved in immune response GO:0002286 28 28 0.000 1.000 1.000 1.000 1.000 0.835 ! B cell activation involved in immune response GO:0002312 26 26 0.000 1.000 1.000 1.000 1.000 0.821 ! immunoglobulin production GO:0002377 46 46 0.000 1.000 1.000 1.000 1.000 0.848 ! immunoglobulin production involved in immunoglobulin mediated immune response GO:0002381 27 27 0.000 1.000 1.000 1.000 1.000 0.814 ! immune response-activating cell surface receptor signaling pathway GO:0002429 114 114 0.000 1.000 1.000 1.000 1.000 0.946 ! production of molecular mediator of immune response GO:0002440 53 53 0.000 1.000 1.000 1.000 1.000 0.865 ! lymphocyte mediated immunity GO:0002449 105 105 0.000 1.000 1.000 1.000 1.000 0.946 ! humoral immune response mediated by circulating immunoglobulin GO:0002455 47 47 0.000 1.000 1.000 1.000 1.000 0.647 ! adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 118 118 0.000 1.000 1.000 1.000 1.000 0.946 ! antigen processing and presentation of peptide antigen via MHC class I GO:0002474 100 100 0.000 1.000 1.000 1.000 1.000 0.946 ! antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent GO:0002479 75 75 0.000 1.000 1.000 1.000 1.000 0.836 ! somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 34 34 0.000 1.000 1.000 1.000 1.000 0.850 GO:0016444|somatic cell DNA recombination, ! platelet degranulation GO:0002576 83 83 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of immunoglobulin production GO:0002637 33 33 0.000 1.000 1.000 1.000 1.000 0.849 ! negative regulation of immune effector process GO:0002698 55 54 0.000 1.000 1.000 1.000 1.000 0.886 ! positive regulation of immune effector process GO:0002699 100 100 0.000 1.000 1.000 1.000 1.000 0.892 ! regulation of production of molecular mediator of immune response GO:0002700 65 65 0.000 1.000 1.000 1.000 1.000 0.888 ! positive regulation of production of molecular mediator of immune response GO:0002702 26 26 0.000 1.000 1.000 1.000 1.000 0.836 ! regulation of leukocyte mediated immunity GO:0002703 94 94 0.000 1.000 1.000 1.000 1.000 0.891 ! positive regulation of leukocyte mediated immunity GO:0002705 46 46 0.000 1.000 1.000 1.000 1.000 0.878 GO:0002708|positive regulation of lymphocyte mediated immunity, ! regulation of lymphocyte mediated immunity GO:0002706 75 75 0.000 1.000 1.000 1.000 1.000 0.890 ! positive regulation of lymphocyte mediated immunity GO:0002708 46 46 0.000 1.000 1.000 1.000 1.000 0.878 GO:0002705|positive regulation of leukocyte mediated immunity, ! regulation of T cell mediated immunity GO:0002709 35 35 0.000 1.000 1.000 1.000 1.000 0.875 ! positive regulation of T cell mediated immunity GO:0002711 25 25 0.000 1.000 1.000 1.000 1.000 0.861 ! regulation of B cell mediated immunity GO:0002712 33 33 0.000 1.000 1.000 1.000 1.000 0.868 ! regulation of cytokine production involved in immune response GO:0002718 41 41 0.000 1.000 1.000 1.000 1.000 0.877 ! positive regulation of cytokine production involved in immune response GO:0002720 21 21 0.000 1.000 1.000 1.000 1.000 0.835 ! regulation of myeloid leukocyte differentiation GO:0002761 78 78 0.000 1.000 1.000 1.000 1.000 0.882 ! negative regulation of myeloid leukocyte differentiation GO:0002762 32 32 0.000 1.000 1.000 1.000 1.000 0.811 ! positive regulation of myeloid leukocyte differentiation GO:0002763 37 37 0.000 1.000 1.000 1.000 1.000 0.858 ! immune response-regulating cell surface receptor signaling pathway GO:0002768 125 125 0.000 1.000 1.000 1.000 1.000 0.946 ! peptide secretion GO:0002790 47 47 0.000 1.000 1.000 1.000 1.000 0.825 ! regulation of adaptive immune response GO:0002819 91 91 0.000 1.000 1.000 1.000 1.000 0.892 ! positive regulation of adaptive immune response GO:0002821 49 49 0.000 1.000 1.000 1.000 1.000 0.887 ! regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 83 83 0.000 1.000 1.000 1.000 1.000 0.892 ! positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 46 46 0.000 1.000 1.000 1.000 1.000 0.885 ! regulation of T-helper 1 type immune response GO:0002825 20 20 0.000 1.000 1.000 1.000 1.000 0.817 ! regulation of type 2 immune response GO:0002828 24 23 0.000 1.000 1.000 1.000 1.000 0.834 ! regulation of inflammatory response to antigenic stimulus GO:0002861 21 21 0.000 1.000 1.000 1.000 1.000 0.834 ! regulation of myeloid leukocyte mediated immunity GO:0002886 23 23 0.000 1.000 1.000 1.000 1.000 0.817 ! regulation of immunoglobulin mediated immune response GO:0002889 32 32 0.000 1.000 1.000 1.000 1.000 0.870 ! regulation of humoral immune response GO:0002920 33 33 0.000 1.000 1.000 1.000 1.000 0.758 ! renal system process involved in regulation of systemic arterial blood pressure GO:0003071 21 21 0.000 1.000 1.000 1.000 1.000 0.845 ! embryonic heart tube morphogenesis GO:0003143 49 49 0.000 1.000 1.000 1.000 1.000 0.874 ! metanephros morphogenesis GO:0003338 26 26 0.000 1.000 1.000 1.000 1.000 0.873 ! epithelial cell morphogenesis GO:0003382 33 33 0.000 1.000 1.000 1.000 1.000 0.835 ! regulation of glycogen biosynthetic process GO:0005979 28 28 0.000 1.000 1.000 1.000 1.000 0.819 GO:0010962|regulation of glucan biosynthetic process, ! aminoglycan catabolic process GO:0006026 66 66 0.000 1.000 1.000 1.000 1.000 0.789 ! glycosaminoglycan catabolic process GO:0006027 59 59 0.000 1.000 1.000 1.000 1.000 0.772 ! amino sugar metabolic process GO:0006040 30 30 0.000 1.000 1.000 1.000 1.000 0.688 ! glucosamine metabolic process GO:0006041 24 24 0.000 1.000 1.000 1.000 1.000 0.675 GO:0006044|N-acetylglucosamine metabolic process, ! N-acetylglucosamine metabolic process GO:0006044 24 24 0.000 1.000 1.000 1.000 1.000 0.675 GO:0006041|glucosamine metabolic process, ! glycerol metabolic process GO:0006071 25 25 0.000 1.000 1.000 1.000 1.000 0.568 ! cellular aldehyde metabolic process GO:0006081 40 40 0.000 1.000 1.000 1.000 1.000 0.829 ! acetyl-CoA metabolic process GO:0006084 44 44 0.000 1.000 1.000 1.000 1.000 0.840 ! gluconeogenesis GO:0006094 44 44 0.000 1.000 1.000 1.000 1.000 0.828 ! tricarboxylic acid cycle GO:0006099 29 29 0.000 1.000 1.000 1.000 1.000 0.772 ! regulation of glycolysis GO:0006110 21 21 0.000 1.000 1.000 1.000 1.000 0.773 ! mitochondrial electron transport, NADH to ubiquinone GO:0006120 38 38 0.000 1.000 1.000 1.000 1.000 0.304 ! ATP catabolic process GO:0006200 71 71 0.000 1.000 1.000 1.000 1.000 0.839 ! pyrimidine base metabolic process GO:0006206 31 31 0.000 1.000 1.000 1.000 1.000 0.796 ! pyrimidine nucleoside metabolic process GO:0006213 51 51 0.000 1.000 1.000 1.000 1.000 0.857 ! pyrimidine nucleotide metabolic process GO:0006220 45 45 0.000 1.000 1.000 1.000 1.000 0.855 ! pyrimidine nucleotide biosynthetic process GO:0006221 31 31 0.000 1.000 1.000 1.000 1.000 0.833 ! DNA-dependent DNA replication initiation GO:0006270 23 23 0.000 1.000 1.000 1.000 1.000 0.484 ! DNA strand elongation involved in DNA replication GO:0006271 34 34 0.000 1.000 1.000 1.000 1.000 0.666 ! regulation of DNA replication GO:0006275 101 101 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of DNA repair GO:0006282 49 49 0.000 1.000 1.000 1.000 1.000 0.815 ! base-excision repair GO:0006284 39 39 0.000 1.000 1.000 1.000 1.000 0.785 ! nucleotide-excision repair, DNA gap filling GO:0006297 22 22 0.000 1.000 1.000 1.000 1.000 0.631 ! mismatch repair GO:0006298 20 20 0.000 1.000 1.000 1.000 1.000 0.728 ! double-strand break repair GO:0006302 98 98 0.000 1.000 1.000 1.000 1.000 0.946 ! mitotic recombination GO:0006312 33 33 0.000 1.000 1.000 1.000 1.000 0.754 ! DNA replication-independent nucleosome assembly GO:0006336 23 23 0.000 1.000 1.000 1.000 1.000 0.426 GO:0034724|DNA replication-independent nucleosome organization, GO:0034080|CenH3-containing nucleosome assembly at centromere, ! chromatin silencing GO:0006342 21 21 0.000 1.000 1.000 1.000 1.000 0.707 ! transcription from RNA polymerase I promoter GO:0006360 25 25 0.000 1.000 1.000 1.000 1.000 0.575 ! transcription initiation from RNA polymerase I promoter GO:0006361 24 24 0.000 1.000 1.000 1.000 1.000 0.570 ! termination of RNA polymerase I transcription GO:0006363 21 21 0.000 1.000 1.000 1.000 1.000 0.497 ! rRNA processing GO:0006364 104 104 0.000 1.000 1.000 1.000 1.000 0.540 ! mRNA capping GO:0006370 30 30 0.000 1.000 1.000 1.000 1.000 0.617 ! mRNA polyadenylation GO:0006378 24 24 0.000 1.000 1.000 1.000 1.000 0.536 ! tRNA modification GO:0006400 20 20 0.000 1.000 1.000 1.000 1.000 0.527 ! 'de novo' protein folding GO:0006458 54 54 0.000 1.000 1.000 1.000 1.000 0.354 ! internal protein amino acid acetylation GO:0006475 92 92 0.000 1.000 1.000 1.000 1.000 0.946 ! protein deacetylation GO:0006476 28 28 0.000 1.000 1.000 1.000 1.000 0.727 ! protein methylation GO:0006479 67 66 0.000 1.000 1.000 1.000 1.000 0.806 GO:0008213|protein alkylation, ! dolichol-linked oligosaccharide biosynthetic process GO:0006488 32 32 0.000 1.000 1.000 1.000 1.000 0.620 ! C-terminal protein lipidation GO:0006501 25 25 0.000 1.000 1.000 1.000 1.000 0.430 ! membrane protein ectodomain proteolysis GO:0006509 22 22 0.000 1.000 1.000 1.000 1.000 0.636 ! protein monoubiquitination GO:0006513 37 37 0.000 1.000 1.000 1.000 1.000 0.682 ! regulation of cellular amino acid metabolic process GO:0006521 58 58 0.000 1.000 1.000 1.000 1.000 0.810 ! cellular modified amino acid metabolic process GO:0006575 152 151 0.000 1.000 1.000 1.000 1.000 0.946 ! polyamine metabolic process GO:0006595 20 20 0.000 1.000 1.000 1.000 1.000 0.671 ! protein targeting to mitochondrion GO:0006626 55 54 0.000 1.000 1.000 1.000 1.000 0.651 ! fatty acid beta-oxidation GO:0006635 44 44 0.000 1.000 1.000 1.000 1.000 0.806 ! acyl-CoA metabolic process GO:0006637 40 40 0.000 1.000 1.000 1.000 1.000 0.802 GO:0035383|thioester metabolic process, ! phosphatidic acid biosynthetic process GO:0006654 31 31 0.000 1.000 1.000 1.000 1.000 0.661 GO:0046473|phosphatidic acid metabolic process, ! glycolipid metabolic process GO:0006664 64 64 0.000 1.000 1.000 1.000 1.000 0.724 ! glycosphingolipid metabolic process GO:0006687 58 58 0.000 1.000 1.000 1.000 1.000 0.720 ! C21-steroid hormone biosynthetic process GO:0006700 20 20 0.000 1.000 1.000 1.000 1.000 0.691 ! coenzyme metabolic process GO:0006732 200 200 0.000 1.000 1.000 1.000 1.000 0.946 ! oxidoreduction coenzyme metabolic process GO:0006733 59 59 0.000 1.000 1.000 1.000 1.000 0.841 ! NADP metabolic process GO:0006739 27 27 0.000 1.000 1.000 1.000 1.000 0.745 ! glutathione metabolic process GO:0006749 50 50 0.000 1.000 1.000 1.000 1.000 0.718 ! folic acid-containing compound metabolic process GO:0006760 24 24 0.000 1.000 1.000 1.000 1.000 0.735 ! water-soluble vitamin metabolic process GO:0006767 66 66 0.000 1.000 1.000 1.000 1.000 0.829 ! porphyrin-containing compound metabolic process GO:0006778 47 47 0.000 1.000 1.000 1.000 1.000 0.799 ! porphyrin-containing compound biosynthetic process GO:0006779 31 31 0.000 1.000 1.000 1.000 1.000 0.708 GO:0033014|tetrapyrrole biosynthetic process, ! heme biosynthetic process GO:0006783 22 22 0.000 1.000 1.000 1.000 1.000 0.620 ! hydrogen transport GO:0006818 59 58 0.000 1.000 1.000 1.000 1.000 0.786 ! chloride transport GO:0006821 26 26 0.000 1.000 1.000 1.000 1.000 0.429 ! iron ion transport GO:0006826 50 50 0.000 1.000 1.000 1.000 1.000 0.709 ! zinc ion transport GO:0006829 22 22 0.000 1.000 1.000 1.000 1.000 0.128 ! mitochondrial transport GO:0006839 115 114 0.000 1.000 1.000 1.000 1.000 0.946 ! cellular iron ion homeostasis GO:0006879 68 68 0.000 1.000 1.000 1.000 1.000 0.798 ! ER to Golgi vesicle-mediated transport GO:0006888 53 53 0.000 1.000 1.000 1.000 1.000 0.466 ! retrograde vesicle-mediated transport, Golgi to ER GO:0006890 24 24 0.000 1.000 1.000 1.000 1.000 0.444 ! intra-Golgi vesicle-mediated transport GO:0006891 31 31 0.000 1.000 1.000 1.000 1.000 0.181 ! Golgi to plasma membrane transport GO:0006893 25 25 0.000 1.000 1.000 1.000 1.000 0.537 ! vesicle targeting GO:0006903 38 38 0.000 1.000 1.000 1.000 1.000 0.692 ! vesicle docking involved in exocytosis GO:0006904 25 25 0.000 1.000 1.000 1.000 1.000 0.519 ! autophagy GO:0006914 92 89 0.000 1.000 1.000 1.000 1.000 0.593 ! acute-phase response GO:0006953 39 39 0.000 1.000 1.000 1.000 1.000 0.583 ! complement activation GO:0006956 51 51 0.000 1.000 1.000 1.000 1.000 0.525 ! complement activation, classical pathway GO:0006958 39 39 0.000 1.000 1.000 1.000 1.000 0.491 ! response to osmotic stress GO:0006970 51 51 0.000 1.000 1.000 1.000 1.000 0.847 ! DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 66 66 0.000 1.000 1.000 1.000 1.000 0.820 GO:0072474|signal transduction involved in mitotic cell cycle G1/S checkpoint, GO:0072413|signal transduction involved in mitotic cell cycle checkpoint, GO:0072431|signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint, ! response to unfolded protein GO:0006986 132 132 0.000 1.000 1.000 1.000 1.000 0.746 ! activation of signaling protein activity involved in unfolded protein response GO:0006987 64 64 0.000 1.000 1.000 1.000 1.000 0.711 ! actin filament organization GO:0007015 113 113 0.000 1.000 1.000 1.000 1.000 0.946 ! Golgi organization GO:0007030 40 40 0.000 1.000 1.000 1.000 1.000 0.558 ! vacuolar transport GO:0007034 44 44 0.000 1.000 1.000 1.000 1.000 0.631 ! lysosomal transport GO:0007041 39 39 0.000 1.000 1.000 1.000 1.000 0.628 ! cell-cell junction assembly GO:0007043 66 66 0.000 1.000 1.000 1.000 1.000 0.769 ! cell-substrate junction assembly GO:0007044 34 34 0.000 1.000 1.000 1.000 1.000 0.671 ! cell cycle arrest GO:0007050 139 139 0.000 1.000 1.000 1.000 1.000 0.946 ! spindle organization GO:0007051 78 76 0.000 1.000 1.000 1.000 1.000 0.744 ! mitotic spindle organization GO:0007052 31 31 0.000 1.000 1.000 1.000 1.000 0.697 ! regulation of S phase of mitotic cell cycle GO:0007090 26 26 0.000 1.000 1.000 1.000 1.000 0.667 ! centrosome cycle GO:0007098 29 29 0.000 1.000 1.000 1.000 1.000 0.604 ! meiotic prophase I GO:0007128 22 22 0.000 1.000 1.000 1.000 1.000 0.536 ! heterophilic cell-cell adhesion GO:0007157 30 29 0.000 1.000 1.000 1.000 1.000 0.464 ! leukocyte cell-cell adhesion GO:0007159 39 39 0.000 1.000 1.000 1.000 1.000 0.812 ! Notch receptor processing GO:0007220 20 20 0.000 1.000 1.000 1.000 1.000 0.664 ! I-kappaB kinase/NF-kappaB cascade GO:0007249 50 50 0.000 1.000 1.000 1.000 1.000 0.721 ! activation of JUN kinase activity GO:0007257 35 35 0.000 1.000 1.000 1.000 1.000 0.721 ! JAK-STAT cascade GO:0007259 48 48 0.000 1.000 1.000 1.000 1.000 0.830 ! Rho protein signal transduction GO:0007266 45 45 0.000 1.000 1.000 1.000 1.000 0.637 ! ectoderm development GO:0007398 22 21 0.000 1.000 1.000 1.000 1.000 0.479 ! sex determination GO:0007530 24 24 0.000 1.000 1.000 1.000 1.000 0.713 ! cell aging GO:0007569 58 58 0.000 1.000 1.000 1.000 1.000 0.868 ! body fluid secretion GO:0007589 59 59 0.000 1.000 1.000 1.000 1.000 0.868 ! lactation GO:0007595 35 35 0.000 1.000 1.000 1.000 1.000 0.842 ! tRNA processing GO:0008033 76 76 0.000 1.000 1.000 1.000 1.000 0.408 ! neuron recognition GO:0008038 30 30 0.000 1.000 1.000 1.000 1.000 0.657 ! actin polymerization or depolymerization GO:0008154 31 31 0.000 1.000 1.000 1.000 1.000 0.646 ! negative regulation of DNA replication GO:0008156 38 38 0.000 1.000 1.000 1.000 1.000 0.751 ! protein alkylation GO:0008213 67 66 0.000 1.000 1.000 1.000 1.000 0.806 GO:0006479|protein methylation, ! isoprenoid biosynthetic process GO:0008299 23 23 0.000 1.000 1.000 1.000 1.000 0.732 ! endosome to lysosome transport GO:0008333 27 27 0.000 1.000 1.000 1.000 1.000 0.440 ! induction of apoptosis by extracellular signals GO:0008624 20 20 0.000 1.000 1.000 1.000 1.000 0.626 ! induction of apoptosis by intracellular signals GO:0008629 66 65 0.000 1.000 1.000 1.000 1.000 0.838 ! DNA damage response, signal transduction resulting in induction of apoptosis GO:0008630 47 46 0.000 1.000 1.000 1.000 1.000 0.801 ! apoptotic mitochondrial changes GO:0008637 40 40 0.000 1.000 1.000 1.000 1.000 0.829 ! fatty acid catabolic process GO:0009062 56 56 0.000 1.000 1.000 1.000 1.000 0.830 ! serine family amino acid metabolic process GO:0009069 32 32 0.000 1.000 1.000 1.000 1.000 0.791 ! aromatic amino acid family metabolic process GO:0009072 28 28 0.000 1.000 1.000 1.000 1.000 0.780 ! branched chain family amino acid metabolic process GO:0009081 23 23 0.000 1.000 1.000 1.000 1.000 0.701 ! coenzyme biosynthetic process GO:0009108 95 95 0.000 1.000 1.000 1.000 1.000 0.946 ! coenzyme catabolic process GO:0009109 36 36 0.000 1.000 1.000 1.000 1.000 0.816 ! nucleoside metabolic process GO:0009116 102 101 0.000 1.000 1.000 1.000 1.000 0.946 ! ribonucleoside metabolic process GO:0009119 78 78 0.000 1.000 1.000 1.000 1.000 0.883 ! purine nucleoside monophosphate metabolic process GO:0009126 29 29 0.000 1.000 1.000 1.000 1.000 0.801 ! purine nucleoside monophosphate biosynthetic process GO:0009127 22 22 0.000 1.000 1.000 1.000 1.000 0.767 GO:0009168|purine ribonucleoside monophosphate biosynthetic process, ! pyrimidine nucleoside triphosphate metabolic process GO:0009147 24 24 0.000 1.000 1.000 1.000 1.000 0.774 ! pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 20 20 0.000 1.000 1.000 1.000 1.000 0.744 ! ribonucleoside monophosphate biosynthetic process GO:0009156 36 36 0.000 1.000 1.000 1.000 1.000 0.845 ! ribonucleoside monophosphate metabolic process GO:0009161 42 42 0.000 1.000 1.000 1.000 1.000 0.855 ! nucleoside biosynthetic process GO:0009163 32 32 0.000 1.000 1.000 1.000 1.000 0.852 ! nucleoside catabolic process GO:0009164 29 29 0.000 1.000 1.000 1.000 1.000 0.825 ! purine ribonucleoside monophosphate metabolic process GO:0009167 28 28 0.000 1.000 1.000 1.000 1.000 0.800 ! purine ribonucleoside monophosphate biosynthetic process GO:0009168 22 22 0.000 1.000 1.000 1.000 1.000 0.767 GO:0009127|purine nucleoside monophosphate biosynthetic process, ! pyrimidine ribonucleotide metabolic process GO:0009218 27 27 0.000 1.000 1.000 1.000 1.000 0.806 ! pyrimidine ribonucleotide biosynthetic process GO:0009220 25 25 0.000 1.000 1.000 1.000 1.000 0.793 ! nucleotide-sugar metabolic process GO:0009225 26 26 0.000 1.000 1.000 1.000 1.000 0.730 ! deoxyribonucleotide metabolic process GO:0009262 35 34 0.000 1.000 1.000 1.000 1.000 0.843 ! response to pH GO:0009268 20 20 0.000 1.000 1.000 1.000 1.000 0.696 ! oligosaccharide biosynthetic process GO:0009312 46 46 0.000 1.000 1.000 1.000 1.000 0.701 ! 2'-deoxyribonucleotide metabolic process GO:0009394 28 28 0.000 1.000 1.000 1.000 1.000 0.832 ! phospholipid catabolic process GO:0009395 23 23 0.000 1.000 1.000 1.000 1.000 0.621 ! RNA modification GO:0009451 58 58 0.000 1.000 1.000 1.000 1.000 0.690 ! RNA capping GO:0009452 31 31 0.000 1.000 1.000 1.000 1.000 0.622 ! detection of chemical stimulus GO:0009593 90 90 0.000 1.000 1.000 1.000 1.000 0.586 ! detection of biotic stimulus GO:0009595 28 28 0.000 1.000 1.000 1.000 1.000 0.834 ! response to fungus GO:0009620 31 31 0.000 1.000 1.000 1.000 1.000 0.632 ! response to salt stress GO:0009651 21 21 0.000 1.000 1.000 1.000 1.000 0.824 ! hormone-mediated signaling pathway GO:0009755 22 22 0.000 1.000 1.000 1.000 1.000 0.689 ! hormone transport GO:0009914 62 61 0.000 1.000 1.000 1.000 1.000 0.856 ! dorsal/ventral axis specification GO:0009950 21 21 0.000 1.000 1.000 1.000 1.000 0.758 ! proximal/distal pattern formation GO:0009954 32 32 0.000 1.000 1.000 1.000 1.000 0.747 ! cell-cell recognition GO:0009988 26 26 0.000 1.000 1.000 1.000 1.000 0.628 ! response to zinc ion GO:0010043 33 33 0.000 1.000 1.000 1.000 1.000 0.693 ! response to X-ray GO:0010165 21 21 0.000 1.000 1.000 1.000 1.000 0.708 ! regulation of G2/M transition of mitotic cell cycle GO:0010389 32 32 0.000 1.000 1.000 1.000 1.000 0.723 ! regulation of platelet activation GO:0010543 23 23 0.000 1.000 1.000 1.000 1.000 0.807 ! regulation of glycoprotein biosynthetic process GO:0010559 25 24 0.000 1.000 1.000 1.000 1.000 0.797 ! negative regulation of cell morphogenesis involved in differentiation GO:0010771 21 21 0.000 1.000 1.000 1.000 1.000 0.803 ! regulation of peptidyl-threonine phosphorylation GO:0010799 20 20 0.000 1.000 1.000 1.000 1.000 0.764 ! negative regulation of cell-substrate adhesion GO:0010812 33 33 0.000 1.000 1.000 1.000 1.000 0.835 ! regulation of mitochondrion organization GO:0010821 48 47 0.000 1.000 1.000 1.000 1.000 0.842 ! positive regulation of mitochondrion organization GO:0010822 29 28 0.000 1.000 1.000 1.000 1.000 0.768 ! telomere maintenance via telomere lengthening GO:0010833 35 35 0.000 1.000 1.000 1.000 1.000 0.783 ! regulation of lipid storage GO:0010883 35 35 0.000 1.000 1.000 1.000 1.000 0.817 ! regulation of glucan biosynthetic process GO:0010962 28 28 0.000 1.000 1.000 1.000 1.000 0.819 GO:0005979|regulation of glycogen biosynthetic process, ! negative regulation of neuron projection development GO:0010977 31 31 0.000 1.000 1.000 1.000 1.000 0.757 ! ferric iron transport GO:0015682 30 30 0.000 1.000 1.000 1.000 1.000 0.592 GO:0033572|transferrin transport, ! organic cation transport GO:0015695 28 28 0.000 1.000 1.000 1.000 1.000 0.701 ! bile acid and bile salt transport GO:0015721 22 20 0.000 1.000 1.000 1.000 1.000 0.490 ! peptide transport GO:0015833 58 58 0.000 1.000 1.000 1.000 1.000 0.841 ! energy coupled proton transport, against electrochemical gradient GO:0015988 30 30 0.000 1.000 1.000 1.000 1.000 0.665 GO:0015991|ATP hydrolysis coupled proton transport, ! ATP hydrolysis coupled proton transport GO:0015991 30 30 0.000 1.000 1.000 1.000 1.000 0.665 GO:0015988|energy coupled proton transport, against electrochemical gradient, ! proton transport GO:0015992 57 56 0.000 1.000 1.000 1.000 1.000 0.777 ! immunoglobulin mediated immune response GO:0016064 79 79 0.000 1.000 1.000 1.000 1.000 0.841 ! rRNA metabolic process GO:0016072 110 110 0.000 1.000 1.000 1.000 1.000 0.571 ! synaptic vesicle exocytosis GO:0016079 29 29 0.000 1.000 1.000 1.000 1.000 0.672 ! macroautophagy GO:0016236 31 30 0.000 1.000 1.000 1.000 1.000 0.515 ! calcium-dependent cell-cell adhesion GO:0016339 26 26 0.000 1.000 1.000 1.000 1.000 0.00663 ! posttranscriptional gene silencing GO:0016441 33 29 0.000 1.000 1.000 1.000 1.000 0.773 GO:0035194|posttranscriptional gene silencing by RNA, ! somatic cell DNA recombination GO:0016444 34 34 0.000 1.000 1.000 1.000 1.000 0.850 GO:0002562|somatic diversification of immune receptors via germline recombination within a single locus, ! somatic diversification of immunoglobulins GO:0016445 30 30 0.000 1.000 1.000 1.000 1.000 0.809 ! somatic recombination of immunoglobulin gene segments GO:0016447 24 24 0.000 1.000 1.000 1.000 1.000 0.812 ! gene silencing GO:0016458 77 73 0.000 1.000 1.000 1.000 1.000 0.854 ! peptide hormone processing GO:0016486 22 22 0.000 1.000 1.000 1.000 1.000 0.459 ! histone methylation GO:0016571 47 46 0.000 1.000 1.000 1.000 1.000 0.789 ! histone acetylation GO:0016573 84 84 0.000 1.000 1.000 1.000 1.000 0.946 ! histone ubiquitination GO:0016574 29 29 0.000 1.000 1.000 1.000 1.000 0.699 ! histone deacetylation GO:0016575 24 24 0.000 1.000 1.000 1.000 1.000 0.707 ! drug metabolic process GO:0017144 34 34 0.000 1.000 1.000 1.000 1.000 0.766 ! regulation of calcium ion-dependent exocytosis GO:0017158 25 25 0.000 1.000 1.000 1.000 1.000 0.683 ! keratan sulfate biosynthetic process GO:0018146 27 27 0.000 1.000 1.000 1.000 1.000 0.336 ! peptide cross-linking GO:0018149 29 29 0.000 1.000 1.000 1.000 1.000 0.325 ! peptidyl-lysine modification GO:0018205 122 122 0.000 1.000 1.000 1.000 1.000 0.946 ! peptidyl-proline modification GO:0018208 29 29 0.000 1.000 1.000 1.000 1.000 0.508 ! internal peptidyl-lysine acetylation GO:0018393 86 86 0.000 1.000 1.000 1.000 1.000 0.946 ! peptidyl-lysine acetylation GO:0018394 88 88 0.000 1.000 1.000 1.000 1.000 0.946 ! C-terminal protein amino acid modification GO:0018410 30 30 0.000 1.000 1.000 1.000 1.000 0.558 ! hexose biosynthetic process GO:0019319 53 53 0.000 1.000 1.000 1.000 1.000 0.846 ! pentose metabolic process GO:0019321 20 20 0.000 1.000 1.000 1.000 1.000 0.699 ! pyridine nucleotide metabolic process GO:0019362 48 48 0.000 1.000 1.000 1.000 1.000 0.834 GO:0046496|nicotinamide nucleotide metabolic process, ! alditol metabolic process GO:0019400 26 26 0.000 1.000 1.000 1.000 1.000 0.575 ! triglyceride biosynthetic process GO:0019432 43 43 0.000 1.000 1.000 1.000 1.000 0.815 ! aromatic compound biosynthetic process GO:0019438 31 31 0.000 1.000 1.000 1.000 1.000 0.810 ! aromatic compound catabolic process GO:0019439 29 29 0.000 1.000 1.000 1.000 1.000 0.778 ! NAD metabolic process GO:0019674 24 24 0.000 1.000 1.000 1.000 1.000 0.751 ! B cell mediated immunity GO:0019724 81 81 0.000 1.000 1.000 1.000 1.000 0.946 ! secondary metabolic process GO:0019748 39 39 0.000 1.000 1.000 1.000 1.000 0.811 ! cytolysis GO:0019835 21 21 0.000 1.000 1.000 1.000 1.000 0.541 ! lipid storage GO:0019915 21 21 0.000 1.000 1.000 1.000 1.000 0.752 ! dorsal spinal cord development GO:0021516 21 20 0.000 1.000 1.000 1.000 1.000 0.560 ! neural tube patterning GO:0021532 33 33 0.000 1.000 1.000 1.000 1.000 0.828 ! cerebellum development GO:0021549 67 66 0.000 1.000 1.000 1.000 1.000 0.862 ! hindbrain morphogenesis GO:0021575 33 33 0.000 1.000 1.000 1.000 1.000 0.834 ! cerebellum morphogenesis GO:0021587 29 29 0.000 1.000 1.000 1.000 1.000 0.819 ! cerebellar cortex development GO:0021695 35 35 0.000 1.000 1.000 1.000 1.000 0.817 ! cerebellar cortex morphogenesis GO:0021696 22 22 0.000 1.000 1.000 1.000 1.000 0.763 ! olfactory bulb development GO:0021772 29 29 0.000 1.000 1.000 1.000 1.000 0.823 ! cerebral cortex cell migration GO:0021795 28 28 0.000 1.000 1.000 1.000 1.000 0.856 ! cerebral cortex development GO:0021987 65 64 0.000 1.000 1.000 1.000 1.000 0.876 ! olfactory lobe development GO:0021988 30 30 0.000 1.000 1.000 1.000 1.000 0.829 ! positive regulation of cell-cell adhesion GO:0022409 32 31 0.000 1.000 1.000 1.000 1.000 0.820 ! cellular process involved in reproduction in multicellular organism GO:0022412 25 24 0.000 1.000 1.000 1.000 1.000 0.585 ! DNA strand elongation GO:0022616 36 36 0.000 1.000 1.000 1.000 1.000 0.691 ! cellular monovalent inorganic cation homeostasis GO:0030004 31 31 0.000 1.000 1.000 1.000 1.000 0.771 ! lamellipodium assembly GO:0030032 28 28 0.000 1.000 1.000 1.000 1.000 0.511 ! peptide hormone secretion GO:0030072 45 45 0.000 1.000 1.000 1.000 1.000 0.817 ! insulin secretion GO:0030073 30 30 0.000 1.000 1.000 1.000 1.000 0.725 ! natural killer cell activation GO:0030101 29 29 0.000 1.000 1.000 1.000 1.000 0.653 ! water homeostasis GO:0030104 23 23 0.000 1.000 1.000 1.000 1.000 0.830 ! sphingolipid catabolic process GO:0030149 20 20 0.000 1.000 1.000 1.000 1.000 0.725 ! regulation of blood coagulation GO:0030193 61 61 0.000 1.000 1.000 1.000 1.000 0.872 GO:1900046|regulation of hemostasis, ! negative regulation of blood coagulation GO:0030195 36 36 0.000 1.000 1.000 1.000 1.000 0.796 GO:1900047|negative regulation of hemostasis, ! hyaluronan metabolic process GO:0030212 25 25 0.000 1.000 1.000 1.000 1.000 0.552 ! T cell differentiation GO:0030217 105 105 0.000 1.000 1.000 1.000 1.000 0.946 ! erythrocyte differentiation GO:0030218 63 63 0.000 1.000 1.000 1.000 1.000 0.850 ! myofibril assembly GO:0030239 37 36 0.000 1.000 1.000 1.000 1.000 0.790 ! entry into host cell GO:0030260 21 21 0.000 1.000 1.000 1.000 1.000 0.742 GO:0044409|entry into host, GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0052126|movement in host environment, ! chromosome condensation GO:0030261 29 29 0.000 1.000 1.000 1.000 1.000 0.512 ! negative regulation of ossification GO:0030279 30 30 0.000 1.000 1.000 1.000 1.000 0.806 ! DNA damage response, signal transduction by p53 class mediator GO:0030330 106 105 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of complement activation GO:0030449 20 20 0.000 1.000 1.000 1.000 1.000 0.524 GO:2000257|regulation of protein activation cascade, ! negative regulation of BMP signaling pathway GO:0030514 34 34 0.000 1.000 1.000 1.000 1.000 0.731 ! intracellular steroid hormone receptor signaling pathway GO:0030518 68 68 0.000 1.000 1.000 1.000 1.000 0.803 ! androgen receptor signaling pathway GO:0030521 43 43 0.000 1.000 1.000 1.000 1.000 0.697 ! male genitalia development GO:0030539 22 22 0.000 1.000 1.000 1.000 1.000 0.748 ! regulation of cellular pH GO:0030641 25 25 0.000 1.000 1.000 1.000 1.000 0.728 ! regulation of actin filament depolymerization GO:0030834 32 32 0.000 1.000 1.000 1.000 1.000 0.679 ! negative regulation of actin filament depolymerization GO:0030835 27 27 0.000 1.000 1.000 1.000 1.000 0.605 ! negative regulation of actin filament polymerization GO:0030837 35 35 0.000 1.000 1.000 1.000 1.000 0.661 ! thyroid gland development GO:0030878 20 20 0.000 1.000 1.000 1.000 1.000 0.780 ! regulation of B cell proliferation GO:0030888 51 51 0.000 1.000 1.000 1.000 1.000 0.861 ! positive regulation of B cell proliferation GO:0030890 35 35 0.000 1.000 1.000 1.000 1.000 0.842 ! regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 24 24 0.000 1.000 1.000 1.000 1.000 0.773 ! endoplasmic reticulum unfolded protein response GO:0030968 84 84 0.000 1.000 1.000 1.000 1.000 0.773 ! microtubule organizing center organization GO:0031023 55 55 0.000 1.000 1.000 1.000 1.000 0.699 ! actomyosin structure organization GO:0031032 49 48 0.000 1.000 1.000 1.000 1.000 0.742 ! gene silencing by RNA GO:0031047 50 46 0.000 1.000 1.000 1.000 1.000 0.785 ! chromatin remodeling at centromere GO:0031055 25 25 0.000 1.000 1.000 1.000 1.000 0.490 ! regulation of histone methylation GO:0031060 24 24 0.000 1.000 1.000 1.000 1.000 0.757 ! embryonic camera-type eye development GO:0031076 35 35 0.000 1.000 1.000 1.000 1.000 0.857 ! lymphocyte costimulation GO:0031294 70 70 0.000 1.000 1.000 1.000 1.000 0.832 ! T cell costimulation GO:0031295 69 69 0.000 1.000 1.000 1.000 1.000 0.828 ! negative regulation of cellular catabolic process GO:0031330 55 55 0.000 1.000 1.000 1.000 1.000 0.852 ! regulation of cell killing GO:0031341 36 36 0.000 1.000 1.000 1.000 1.000 0.864 ! positive regulation of cell killing GO:0031343 29 29 0.000 1.000 1.000 1.000 1.000 0.850 ! negative regulation of protein ubiquitination GO:0031397 94 94 0.000 1.000 1.000 1.000 1.000 0.946 ! keratinization GO:0031424 44 44 0.000 1.000 1.000 1.000 1.000 0.000936 ! DNA integrity checkpoint GO:0031570 141 140 0.000 1.000 1.000 1.000 1.000 0.946 ! mitotic cell cycle G1/S transition DNA damage checkpoint GO:0031571 73 73 0.000 1.000 1.000 1.000 1.000 0.830 ! G2/M transition DNA damage checkpoint GO:0031572 32 32 0.000 1.000 1.000 1.000 1.000 0.675 ! mitotic cell cycle G1/S transition checkpoint GO:0031575 82 82 0.000 1.000 1.000 1.000 1.000 0.946 ! G2/M transition checkpoint GO:0031576 41 41 0.000 1.000 1.000 1.000 1.000 0.738 ! lipopolysaccharide-mediated signaling pathway GO:0031663 26 26 0.000 1.000 1.000 1.000 1.000 0.843 ! regulation of protein autophosphorylation GO:0031952 23 23 0.000 1.000 1.000 1.000 1.000 0.762 ! regulation of TOR signaling cascade GO:0032006 40 38 0.000 1.000 1.000 1.000 1.000 0.658 ! regulation of nuclease activity GO:0032069 72 72 0.000 1.000 1.000 1.000 1.000 0.766 ! positive regulation of nuclease activity GO:0032075 66 66 0.000 1.000 1.000 1.000 1.000 0.730 ! positive regulation of protein binding GO:0032092 41 41 0.000 1.000 1.000 1.000 1.000 0.807 ! regulation of response to extracellular stimulus GO:0032104 34 34 0.000 1.000 1.000 1.000 1.000 0.822 GO:0032107|regulation of response to nutrient levels, ! regulation of response to nutrient levels GO:0032107 34 34 0.000 1.000 1.000 1.000 1.000 0.822 GO:0032104|regulation of response to extracellular stimulus, ! telomere organization GO:0032200 59 59 0.000 1.000 1.000 1.000 1.000 0.839 ! telomere maintenance via semi-conservative replication GO:0032201 22 22 0.000 1.000 1.000 1.000 1.000 0.669 ! regulation of ARF GTPase activity GO:0032312 32 32 0.000 1.000 1.000 1.000 1.000 0.00250 ! regulation of lipid transport GO:0032368 60 60 0.000 1.000 1.000 1.000 1.000 0.889 ! negative regulation of lipid transport GO:0032369 21 21 0.000 1.000 1.000 1.000 1.000 0.847 ! positive regulation of lipid transport GO:0032370 29 29 0.000 1.000 1.000 1.000 1.000 0.857 ! regulation of sterol transport GO:0032371 32 32 0.000 1.000 1.000 1.000 1.000 0.874 GO:0032374|regulation of cholesterol transport, ! regulation of cholesterol transport GO:0032374 32 32 0.000 1.000 1.000 1.000 1.000 0.874 GO:0032371|regulation of sterol transport, ! DNA geometric change GO:0032392 31 31 0.000 1.000 1.000 1.000 1.000 0.688 ! regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032434 57 57 0.000 1.000 1.000 1.000 1.000 0.832 ! positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 35 35 0.000 1.000 1.000 1.000 1.000 0.759 ! regulation of protein oligomerization GO:0032459 21 21 0.000 1.000 1.000 1.000 1.000 0.734 ! regulation of cytokinesis GO:0032465 28 28 0.000 1.000 1.000 1.000 1.000 0.757 ! regulation of Cdc42 protein signal transduction GO:0032489 21 21 0.000 1.000 1.000 1.000 1.000 0.615 ! maintenance of protein location in cell GO:0032507 84 84 0.000 1.000 1.000 1.000 1.000 0.867 ! DNA duplex unwinding GO:0032508 30 30 0.000 1.000 1.000 1.000 1.000 0.694 ! regulation of interleukin-10 production GO:0032653 24 24 0.000 1.000 1.000 1.000 1.000 0.831 ! regulation of interleukin-2 production GO:0032663 40 40 0.000 1.000 1.000 1.000 1.000 0.859 ! regulation of interleukin-4 production GO:0032673 24 24 0.000 1.000 1.000 1.000 1.000 0.821 ! negative regulation of interferon-gamma production GO:0032689 26 26 0.000 1.000 1.000 1.000 1.000 0.854 ! negative regulation of tumor necrosis factor production GO:0032720 28 28 0.000 1.000 1.000 1.000 1.000 0.832 ! positive regulation of chemokine production GO:0032722 30 30 0.000 1.000 1.000 1.000 1.000 0.876 ! positive regulation of interleukin-8 production GO:0032757 20 20 0.000 1.000 1.000 1.000 1.000 0.795 ! regulation of natural killer cell activation GO:0032814 22 22 0.000 1.000 1.000 1.000 1.000 0.791 ! activation of Ras GTPase activity GO:0032856 28 28 0.000 1.000 1.000 1.000 1.000 0.760 ! activation of Rho GTPase activity GO:0032862 20 20 0.000 1.000 1.000 1.000 1.000 0.648 ! regulation of polysaccharide metabolic process GO:0032881 35 35 0.000 1.000 1.000 1.000 1.000 0.851 ! regulation of polysaccharide biosynthetic process GO:0032885 32 32 0.000 1.000 1.000 1.000 1.000 0.841 ! regulation of organic acid transport GO:0032890 30 30 0.000 1.000 1.000 1.000 1.000 0.856 ! regulation of activin receptor signaling pathway GO:0032925 20 20 0.000 1.000 1.000 1.000 1.000 0.791 ! mononuclear cell proliferation GO:0032943 54 54 0.000 1.000 1.000 1.000 1.000 0.859 ! negative regulation of mononuclear cell proliferation GO:0032945 53 53 0.000 1.000 1.000 1.000 1.000 0.860 GO:0050672|negative regulation of lymphocyte proliferation, ! regulation of mast cell activation GO:0033003 24 24 0.000 1.000 1.000 1.000 1.000 0.816 ! tetrapyrrole metabolic process GO:0033013 48 48 0.000 1.000 1.000 1.000 1.000 0.804 ! tetrapyrrole biosynthetic process GO:0033014 31 31 0.000 1.000 1.000 1.000 1.000 0.708 GO:0006779|porphyrin-containing compound biosynthetic process, ! T cell differentiation in thymus GO:0033077 45 45 0.000 1.000 1.000 1.000 1.000 0.858 ! regulation of T cell differentiation in thymus GO:0033081 20 20 0.000 1.000 1.000 1.000 1.000 0.740 ! mitochondrial respiratory chain complex assembly GO:0033108 24 22 0.000 1.000 1.000 1.000 1.000 0.466 ! cell cycle cytokinesis GO:0033205 24 24 0.000 1.000 1.000 1.000 1.000 0.652 ! tumor necrosis factor-mediated signaling pathway GO:0033209 26 25 0.000 1.000 1.000 1.000 1.000 0.588 ! transferrin transport GO:0033572 30 30 0.000 1.000 1.000 1.000 1.000 0.592 GO:0015682|ferric iron transport, ! nucleoside bisphosphate metabolic process GO:0033865 29 29 0.000 1.000 1.000 1.000 1.000 0.702 ! CenH3-containing nucleosome assembly at centromere GO:0034080 23 23 0.000 1.000 1.000 1.000 1.000 0.426 GO:0034724|DNA replication-independent nucleosome organization, GO:0006336|DNA replication-independent nucleosome assembly, ! erythrocyte homeostasis GO:0034101 70 70 0.000 1.000 1.000 1.000 1.000 0.858 ! regulation of tissue remodeling GO:0034103 40 40 0.000 1.000 1.000 1.000 1.000 0.870 ! positive regulation of tissue remodeling GO:0034105 20 20 0.000 1.000 1.000 1.000 1.000 0.821 ! homotypic cell-cell adhesion GO:0034109 30 30 0.000 1.000 1.000 1.000 1.000 0.795 ! regulation of toll-like receptor signaling pathway GO:0034121 28 28 0.000 1.000 1.000 1.000 1.000 0.826 ! cell junction assembly GO:0034329 144 144 0.000 1.000 1.000 1.000 1.000 0.946 ! cell junction organization GO:0034330 169 169 0.000 1.000 1.000 1.000 1.000 0.946 ! adherens junction organization GO:0034332 43 43 0.000 1.000 1.000 1.000 1.000 0.597 ! macromolecular complex remodeling GO:0034367 23 23 0.000 1.000 1.000 1.000 1.000 0.827 GO:0034368|protein-lipid complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! protein-lipid complex remodeling GO:0034368 23 23 0.000 1.000 1.000 1.000 1.000 0.827 GO:0034367|macromolecular complex remodeling, GO:0034369|plasma lipoprotein particle remodeling, ! plasma lipoprotein particle remodeling GO:0034369 23 23 0.000 1.000 1.000 1.000 1.000 0.827 GO:0034367|macromolecular complex remodeling, GO:0034368|protein-lipid complex remodeling, ! plasma lipoprotein particle clearance GO:0034381 21 21 0.000 1.000 1.000 1.000 1.000 0.829 ! response to fluid shear stress GO:0034405 22 22 0.000 1.000 1.000 1.000 1.000 0.831 ! substrate adhesion-dependent cell spreading GO:0034446 26 26 0.000 1.000 1.000 1.000 1.000 0.695 ! microtubule anchoring GO:0034453 26 26 0.000 1.000 1.000 1.000 1.000 0.719 ! protein localization to chromosome GO:0034502 24 23 0.000 1.000 1.000 1.000 1.000 0.766 ! cellular response to unfolded protein GO:0034620 85 85 0.000 1.000 1.000 1.000 1.000 0.777 ! response to gonadotropin stimulus GO:0034698 23 22 0.000 1.000 1.000 1.000 1.000 0.806 ! DNA replication-independent nucleosome organization GO:0034724 23 23 0.000 1.000 1.000 1.000 1.000 0.426 GO:0034080|CenH3-containing nucleosome assembly at centromere, GO:0006336|DNA replication-independent nucleosome assembly, ! histone lysine methylation GO:0034968 33 33 0.000 1.000 1.000 1.000 1.000 0.688 ! somatic stem cell maintenance GO:0035019 36 36 0.000 1.000 1.000 1.000 1.000 0.811 ! regulation of Rac protein signal transduction GO:0035020 24 24 0.000 1.000 1.000 1.000 1.000 0.696 ! embryonic heart tube development GO:0035050 62 62 0.000 1.000 1.000 1.000 1.000 0.883 ! establishment or maintenance of apical/basal cell polarity GO:0035088 21 21 0.000 1.000 1.000 1.000 1.000 0.707 GO:0061245|establishment or maintenance of bipolar cell polarity, ! embryonic forelimb morphogenesis GO:0035115 29 29 0.000 1.000 1.000 1.000 1.000 0.749 ! embryonic hemopoiesis GO:0035162 24 24 0.000 1.000 1.000 1.000 1.000 0.705 ! social behavior GO:0035176 33 33 0.000 1.000 1.000 1.000 1.000 0.811 ! posttranscriptional gene silencing by RNA GO:0035194 33 29 0.000 1.000 1.000 1.000 1.000 0.773 GO:0016441|posttranscriptional gene silencing, ! gene silencing by miRNA GO:0035195 28 24 0.000 1.000 1.000 1.000 1.000 0.731 ! hippo signaling cascade GO:0035329 24 24 0.000 1.000 1.000 1.000 1.000 0.277 ! long-chain fatty-acyl-CoA metabolic process GO:0035336 24 24 0.000 1.000 1.000 1.000 1.000 0.762 ! fatty-acyl-CoA metabolic process GO:0035337 27 27 0.000 1.000 1.000 1.000 1.000 0.773 ! thioester metabolic process GO:0035383 40 40 0.000 1.000 1.000 1.000 1.000 0.802 GO:0006637|acyl-CoA metabolic process, ! thioester biosynthetic process GO:0035384 20 20 0.000 1.000 1.000 1.000 1.000 0.724 GO:0046949|fatty-acyl-CoA biosynthetic process, GO:0071616|acyl-CoA biosynthetic process, ! regulation of catenin import into nucleus GO:0035412 22 22 0.000 1.000 1.000 1.000 1.000 0.776 ! non-canonical Wnt receptor signaling pathway GO:0035567 32 32 0.000 1.000 1.000 1.000 1.000 0.850 ! protein deacylation GO:0035601 29 29 0.000 1.000 1.000 1.000 1.000 0.739 ! CD4-positive, alpha-beta T cell activation GO:0035710 22 22 0.000 1.000 1.000 1.000 1.000 0.813 ! modification of morphology or physiology of other organism GO:0035821 44 44 0.000 1.000 1.000 1.000 1.000 0.874 GO:0051817|modification of morphology or physiology of other organism involved in symbiotic interaction, ! response to topologically incorrect protein GO:0035966 139 139 0.000 1.000 1.000 1.000 1.000 0.776 ! cellular response to topologically incorrect protein GO:0035967 90 90 0.000 1.000 1.000 1.000 1.000 0.794 ! replacement ossification GO:0036075 22 22 0.000 1.000 1.000 1.000 1.000 0.708 GO:0001958|endochondral ossification, ! NIK/NF-kappaB cascade GO:0038061 23 23 0.000 1.000 1.000 1.000 1.000 0.637 ! regulation of meiosis GO:0040020 22 22 0.000 1.000 1.000 1.000 1.000 0.710 ! negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 39 39 0.000 1.000 1.000 1.000 1.000 0.705 ! T cell proliferation GO:0042098 35 35 0.000 1.000 1.000 1.000 1.000 0.775 ! positive regulation of T cell proliferation GO:0042102 69 69 0.000 1.000 1.000 1.000 1.000 0.888 ! positive regulation of cytokine biosynthetic process GO:0042108 59 59 0.000 1.000 1.000 1.000 1.000 0.881 ! regulation of T cell proliferation GO:0042129 107 107 0.000 1.000 1.000 1.000 1.000 0.892 ! negative regulation of T cell proliferation GO:0042130 42 42 0.000 1.000 1.000 1.000 1.000 0.852 ! heme metabolic process GO:0042168 30 30 0.000 1.000 1.000 1.000 1.000 0.729 ! ribosome biogenesis GO:0042254 150 150 0.000 1.000 1.000 1.000 1.000 0.571 ! purine nucleoside metabolic process GO:0042278 48 47 0.000 1.000 1.000 1.000 1.000 0.831 ! keratan sulfate metabolic process GO:0042339 32 32 0.000 1.000 1.000 1.000 1.000 0.475 ! cellular modified amino acid biosynthetic process GO:0042398 42 42 0.000 1.000 1.000 1.000 1.000 0.754 ! cellular biogenic amine catabolic process GO:0042402 24 24 0.000 1.000 1.000 1.000 1.000 0.798 ! pigment metabolic process GO:0042440 60 60 0.000 1.000 1.000 1.000 1.000 0.859 ! regulation of odontogenesis GO:0042481 25 25 0.000 1.000 1.000 1.000 1.000 0.775 ! auditory receptor cell differentiation GO:0042491 26 26 0.000 1.000 1.000 1.000 1.000 0.751 ! pteridine-containing compound metabolic process GO:0042558 37 37 0.000 1.000 1.000 1.000 1.000 0.807 ! pteridine-containing compound biosynthetic process GO:0042559 22 22 0.000 1.000 1.000 1.000 1.000 0.745 ! retinoic acid metabolic process GO:0042573 21 21 0.000 1.000 1.000 1.000 1.000 0.725 ! antigen processing and presentation of exogenous peptide antigen via MHC class I GO:0042590 79 79 0.000 1.000 1.000 1.000 1.000 0.840 ! embryonic digit morphogenesis GO:0042733 46 46 0.000 1.000 1.000 1.000 1.000 0.827 ! signal transduction in response to DNA damage GO:0042770 132 131 0.000 1.000 1.000 1.000 1.000 0.946 ! DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis GO:0042771 27 26 0.000 1.000 1.000 1.000 1.000 0.718 ! protein ubiquitination involved in ubiquitin-dependent protein catabolic process GO:0042787 48 47 0.000 1.000 1.000 1.000 1.000 0.151 ! T cell homeostasis GO:0043029 25 25 0.000 1.000 1.000 1.000 1.000 0.823 ! cellular metabolic compound salvage GO:0043094 35 35 0.000 1.000 1.000 1.000 1.000 0.842 ! regulation of I-kappaB kinase/NF-kappaB cascade GO:0043122 174 174 0.000 1.000 1.000 1.000 1.000 0.946 ! positive regulation of I-kappaB kinase/NF-kappaB cascade GO:0043123 143 143 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of I-kappaB kinase/NF-kappaB cascade GO:0043124 28 28 0.000 1.000 1.000 1.000 1.000 0.735 ! apical junction assembly GO:0043297 39 39 0.000 1.000 1.000 1.000 1.000 0.546 ! regulation of leukocyte degranulation GO:0043300 21 21 0.000 1.000 1.000 1.000 1.000 0.800 ! response to exogenous dsRNA GO:0043330 21 21 0.000 1.000 1.000 1.000 1.000 0.726 ! response to dsRNA GO:0043331 39 38 0.000 1.000 1.000 1.000 1.000 0.822 ! CD4-positive, alpha-beta T cell differentiation GO:0043367 21 21 0.000 1.000 1.000 1.000 1.000 0.805 ! regulation of CD4-positive, alpha-beta T cell differentiation GO:0043370 28 28 0.000 1.000 1.000 1.000 1.000 0.857 ! regulation of generation of precursor metabolites and energy GO:0043467 56 56 0.000 1.000 1.000 1.000 1.000 0.868 ! regulation of carbohydrate catabolic process GO:0043470 29 29 0.000 1.000 1.000 1.000 1.000 0.816 GO:0043471|regulation of cellular carbohydrate catabolic process, ! regulation of cellular carbohydrate catabolic process GO:0043471 29 29 0.000 1.000 1.000 1.000 1.000 0.816 GO:0043470|regulation of carbohydrate catabolic process, ! histone exchange GO:0043486 27 27 0.000 1.000 1.000 1.000 1.000 0.497 ! regulation of RNA stability GO:0043487 41 41 0.000 1.000 1.000 1.000 1.000 0.702 ! regulation of mRNA stability GO:0043488 37 37 0.000 1.000 1.000 1.000 1.000 0.681 ! RNA stabilization GO:0043489 26 26 0.000 1.000 1.000 1.000 1.000 0.674 GO:0048255|mRNA stabilization, ! protein kinase B signaling cascade GO:0043491 27 27 0.000 1.000 1.000 1.000 1.000 0.815 ! regulation of JUN kinase activity GO:0043506 72 72 0.000 1.000 1.000 1.000 1.000 0.858 ! positive regulation of JUN kinase activity GO:0043507 58 58 0.000 1.000 1.000 1.000 1.000 0.837 ! regulation of DNA damage response, signal transduction by p53 class mediator GO:0043516 25 25 0.000 1.000 1.000 1.000 1.000 0.765 ! blood vessel endothelial cell migration GO:0043534 22 22 0.000 1.000 1.000 1.000 1.000 0.790 ! regulation of insulin-like growth factor receptor signaling pathway GO:0043567 21 21 0.000 1.000 1.000 1.000 1.000 0.716 ! skin development GO:0043588 51 51 0.000 1.000 1.000 1.000 1.000 0.811 ! cellular amide metabolic process GO:0043603 23 23 0.000 1.000 1.000 1.000 1.000 0.771 ! RNA polyadenylation GO:0043631 25 25 0.000 1.000 1.000 1.000 1.000 0.537 ! negative regulation of multi-organism process GO:0043901 23 23 0.000 1.000 1.000 1.000 1.000 0.825 ! regulation of symbiosis, encompassing mutualism through parasitism GO:0043903 23 23 0.000 1.000 1.000 1.000 1.000 0.813 ! modulation by host of viral transcription GO:0043921 20 20 0.000 1.000 1.000 1.000 1.000 0.769 GO:0052472|modulation by host of symbiont transcription, ! exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay GO:0043928 26 26 0.000 1.000 1.000 1.000 1.000 0.296 GO:0000291|nuclear-transcribed mRNA catabolic process, exonucleolytic, ! histone H3 acetylation GO:0043966 42 42 0.000 1.000 1.000 1.000 1.000 0.691 ! histone H4 acetylation GO:0043967 41 41 0.000 1.000 1.000 1.000 1.000 0.730 ! positive regulation of cellular component biogenesis GO:0044089 21 21 0.000 1.000 1.000 1.000 1.000 0.721 ! cellular lipid catabolic process GO:0044242 116 116 0.000 1.000 1.000 1.000 1.000 0.946 ! glycerol ether catabolic process GO:0044269 20 20 0.000 1.000 1.000 1.000 1.000 0.710 GO:0046464|acylglycerol catabolic process, GO:0046461|neutral lipid catabolic process, ! sulfur compound catabolic process GO:0044273 35 35 0.000 1.000 1.000 1.000 1.000 0.719 ! DNA excision GO:0044349 21 21 0.000 1.000 1.000 1.000 1.000 0.653 GO:0000718|nucleotide-excision repair, DNA damage removal, ! entry into host GO:0044409 21 21 0.000 1.000 1.000 1.000 1.000 0.742 GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0030260|entry into host cell, GO:0052126|movement in host environment, ! T cell selection GO:0045058 25 25 0.000 1.000 1.000 1.000 1.000 0.804 ! regulation of bone resorption GO:0045124 25 25 0.000 1.000 1.000 1.000 1.000 0.821 ! meiotic chromosome segregation GO:0045132 22 21 0.000 1.000 1.000 1.000 1.000 0.694 ! sarcomere organization GO:0045214 20 20 0.000 1.000 1.000 1.000 1.000 0.674 ! cell-cell junction organization GO:0045216 122 122 0.000 1.000 1.000 1.000 1.000 0.946 ! myoblast differentiation GO:0045445 22 22 0.000 1.000 1.000 1.000 1.000 0.734 ! bone resorption GO:0045453 20 20 0.000 1.000 1.000 1.000 1.000 0.722 ! regulation of T cell differentiation GO:0045580 82 81 0.000 1.000 1.000 1.000 1.000 0.888 ! negative regulation of T cell differentiation GO:0045581 24 23 0.000 1.000 1.000 1.000 1.000 0.809 ! positive regulation of T cell differentiation GO:0045582 53 53 0.000 1.000 1.000 1.000 1.000 0.882 ! regulation of lymphocyte differentiation GO:0045619 105 104 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of lymphocyte differentiation GO:0045620 33 32 0.000 1.000 1.000 1.000 1.000 0.855 ! positive regulation of lymphocyte differentiation GO:0045621 63 63 0.000 1.000 1.000 1.000 1.000 0.885 ! regulation of T-helper cell differentiation GO:0045622 22 22 0.000 1.000 1.000 1.000 1.000 0.839 ! regulation of myeloid cell differentiation GO:0045637 133 133 0.000 1.000 1.000 1.000 1.000 0.946 ! negative regulation of myeloid cell differentiation GO:0045638 60 60 0.000 1.000 1.000 1.000 1.000 0.857 ! positive regulation of myeloid cell differentiation GO:0045639 63 63 0.000 1.000 1.000 1.000 1.000 0.882 ! regulation of erythrocyte differentiation GO:0045646 33 33 0.000 1.000 1.000 1.000 1.000 0.813 ! regulation of myoblast differentiation GO:0045661 21 20 0.000 1.000 1.000 1.000 1.000 0.745 ! negative regulation of osteoblast differentiation GO:0045668 34 34 0.000 1.000 1.000 1.000 1.000 0.809 ! regulation of osteoclast differentiation GO:0045670 40 40 0.000 1.000 1.000 1.000 1.000 0.805 ! positive regulation of glial cell differentiation GO:0045687 25 24 0.000 1.000 1.000 1.000 1.000 0.827 ! positive regulation of translation GO:0045727 55 54 0.000 1.000 1.000 1.000 1.000 0.786 ! positive regulation of protein catabolic process GO:0045732 80 80 0.000 1.000 1.000 1.000 1.000 0.869 ! positive regulation of DNA repair GO:0045739 27 27 0.000 1.000 1.000 1.000 1.000 0.736 ! positive regulation of DNA replication GO:0045740 50 50 0.000 1.000 1.000 1.000 1.000 0.870 ! negative regulation of endocytosis GO:0045806 26 26 0.000 1.000 1.000 1.000 1.000 0.737 ! negative regulation of gene expression, epigenetic GO:0045814 25 25 0.000 1.000 1.000 1.000 1.000 0.718 ! negative regulation of proteolysis GO:0045861 37 37 0.000 1.000 1.000 1.000 1.000 0.789 ! positive regulation of proteolysis GO:0045862 62 62 0.000 1.000 1.000 1.000 1.000 0.851 ! positive regulation of exocytosis GO:0045921 34 34 0.000 1.000 1.000 1.000 1.000 0.792 ! positive regulation of steroid metabolic process GO:0045940 20 20 0.000 1.000 1.000 1.000 1.000 0.853 ! regulation of activated T cell proliferation GO:0046006 25 25 0.000 1.000 1.000 1.000 1.000 0.826 ! purine ribonucleoside metabolic process GO:0046128 44 44 0.000 1.000 1.000 1.000 1.000 0.843 ! pyrimidine ribonucleoside metabolic process GO:0046131 34 34 0.000 1.000 1.000 1.000 1.000 0.833 ! pyrimidine nucleoside catabolic process GO:0046135 20 20 0.000 1.000 1.000 1.000 1.000 0.747 ! pigment biosynthetic process GO:0046148 47 47 0.000 1.000 1.000 1.000 1.000 0.831 ! regulation of fatty acid oxidation GO:0046320 37 37 0.000 1.000 1.000 1.000 1.000 0.787 ! negative regulation of JNK cascade GO:0046329 21 21 0.000 1.000 1.000 1.000 1.000 0.690 ! acetyl-CoA catabolic process GO:0046356 30 30 0.000 1.000 1.000 1.000 1.000 0.780 ! monosaccharide biosynthetic process GO:0046364 69 69 0.000 1.000 1.000 1.000 1.000 0.871 ! neutral lipid biosynthetic process GO:0046460 47 47 0.000 1.000 1.000 1.000 1.000 0.826 GO:0046463|acylglycerol biosynthetic process, ! neutral lipid catabolic process GO:0046461 20 20 0.000 1.000 1.000 1.000 1.000 0.710 GO:0044269|glycerol ether catabolic process, GO:0046464|acylglycerol catabolic process, ! acylglycerol biosynthetic process GO:0046463 47 47 0.000 1.000 1.000 1.000 1.000 0.826 GO:0046460|neutral lipid biosynthetic process, ! acylglycerol catabolic process GO:0046464 20 20 0.000 1.000 1.000 1.000 1.000 0.710 GO:0044269|glycerol ether catabolic process, GO:0046461|neutral lipid catabolic process, ! membrane lipid catabolic process GO:0046466 21 21 0.000 1.000 1.000 1.000 1.000 0.732 ! phosphatidic acid metabolic process GO:0046473 31 31 0.000 1.000 1.000 1.000 1.000 0.661 GO:0006654|phosphatidic acid biosynthetic process, ! nicotinamide nucleotide metabolic process GO:0046496 48 48 0.000 1.000 1.000 1.000 1.000 0.834 GO:0019362|pyridine nucleotide metabolic process, ! glycerolipid catabolic process GO:0046503 26 26 0.000 1.000 1.000 1.000 1.000 0.743 ! glycerol ether biosynthetic process GO:0046504 52 52 0.000 1.000 1.000 1.000 1.000 0.838 ! negative regulation of Ras protein signal transduction GO:0046580 30 30 0.000 1.000 1.000 1.000 1.000 0.581 ! regulation of insulin receptor signaling pathway GO:0046626 29 29 0.000 1.000 1.000 1.000 1.000 0.817 ! negative regulation of insulin receptor signaling pathway GO:0046627 21 21 0.000 1.000 1.000 1.000 1.000 0.787 ! alpha-beta T cell activation GO:0046631 40 40 0.000 1.000 1.000 1.000 1.000 0.862 ! alpha-beta T cell differentiation GO:0046632 35 35 0.000 1.000 1.000 1.000 1.000 0.848 ! positive regulation of alpha-beta T cell activation GO:0046635 43 43 0.000 1.000 1.000 1.000 1.000 0.877 ! regulation of alpha-beta T cell differentiation GO:0046637 41 41 0.000 1.000 1.000 1.000 1.000 0.877 ! positive regulation of alpha-beta T cell differentiation GO:0046638 30 30 0.000 1.000 1.000 1.000 1.000 0.852 ! lymphocyte proliferation GO:0046651 52 52 0.000 1.000 1.000 1.000 1.000 0.854 ! response to antibiotic GO:0046677 39 38 0.000 1.000 1.000 1.000 1.000 0.820 ! response to cadmium ion GO:0046686 33 33 0.000 1.000 1.000 1.000 1.000 0.800 ! regulation of viral transcription GO:0046782 72 68 0.000 1.000 1.000 1.000 1.000 0.823 ! lipid phosphorylation GO:0046834 23 23 0.000 1.000 1.000 1.000 1.000 0.672 ! filopodium assembly GO:0046847 24 24 0.000 1.000 1.000 1.000 1.000 0.308 ! bone remodeling GO:0046849 36 36 0.000 1.000 1.000 1.000 1.000 0.811 ! regulation of bone remodeling GO:0046850 28 28 0.000 1.000 1.000 1.000 1.000 0.829 ! phosphatidylinositol phosphorylation GO:0046854 22 22 0.000 1.000 1.000 1.000 1.000 0.671 ! hormone secretion GO:0046879 58 57 0.000 1.000 1.000 1.000 1.000 0.853 ! fatty-acyl-CoA biosynthetic process GO:0046949 20 20 0.000 1.000 1.000 1.000 1.000 0.724 GO:0035384|thioester biosynthetic process, GO:0071616|acyl-CoA biosynthetic process, ! vascular endothelial growth factor receptor signaling pathway GO:0048010 26 26 0.000 1.000 1.000 1.000 1.000 0.807 ! vesicle targeting, to, from or within Golgi GO:0048199 27 27 0.000 1.000 1.000 1.000 1.000 0.636 ! mRNA stabilization GO:0048255 26 26 0.000 1.000 1.000 1.000 1.000 0.674 GO:0043489|RNA stabilization, ! regulation of retinoic acid receptor signaling pathway GO:0048385 39 38 0.000 1.000 1.000 1.000 1.000 0.0919 ! negative regulation of retinoic acid receptor signaling pathway GO:0048387 34 33 0.000 1.000 1.000 1.000 1.000 0.00764 ! positive regulation of viral reproduction GO:0048524 87 83 0.000 1.000 1.000 1.000 1.000 0.946 ! spleen development GO:0048536 26 26 0.000 1.000 1.000 1.000 1.000 0.715 ! thymus development GO:0048538 33 33 0.000 1.000 1.000 1.000 1.000 0.819 ! embryonic camera-type eye morphogenesis GO:0048596 26 26 0.000 1.000 1.000 1.000 1.000 0.843 ! negative regulation of developmental growth GO:0048640 27 27 0.000 1.000 1.000 1.000 1.000 0.810 ! embryonic cranial skeleton morphogenesis GO:0048701 35 35 0.000 1.000 1.000 1.000 1.000 0.840 ! embryonic skeletal system morphogenesis GO:0048704 85 85 0.000 1.000 1.000 1.000 1.000 0.946 ! embryonic skeletal system development GO:0048706 114 114 0.000 1.000 1.000 1.000 1.000 0.946 ! tissue remodeling GO:0048771 85 85 0.000 1.000 1.000 1.000 1.000 0.887 ! genitalia development GO:0048806 36 36 0.000 1.000 1.000 1.000 1.000 0.832 ! erythrocyte development GO:0048821 21 21 0.000 1.000 1.000 1.000 1.000 0.728 ! homeostasis of number of cells within a tissue GO:0048873 23 23 0.000 1.000 1.000 1.000 1.000 0.649 ! positive regulation of viral transcription GO:0050434 59 55 0.000 1.000 1.000 1.000 1.000 0.760 ! cytokine secretion GO:0050663 26 26 0.000 1.000 1.000 1.000 1.000 0.779 ! negative regulation of lymphocyte proliferation GO:0050672 53 53 0.000 1.000 1.000 1.000 1.000 0.860 GO:0032945|negative regulation of mononuclear cell proliferation, ! regulation of interleukin-1 secretion GO:0050704 21 21 0.000 1.000 1.000 1.000 1.000 0.803 ! regulation of cytokine secretion GO:0050707 80 79 0.000 1.000 1.000 1.000 1.000 0.884 ! negative regulation of cytokine secretion GO:0050710 24 23 0.000 1.000 1.000 1.000 1.000 0.795 ! positive regulation of cytokine secretion GO:0050715 56 56 0.000 1.000 1.000 1.000 1.000 0.866 ! negative regulation of immune response GO:0050777 55 54 0.000 1.000 1.000 1.000 1.000 0.877 ! positive regulation of coagulation GO:0050820 20 20 0.000 1.000 1.000 1.000 1.000 0.786 ! protein stabilization GO:0050821 68 68 0.000 1.000 1.000 1.000 1.000 0.841 ! defense response to Gram-positive bacterium GO:0050830 33 33 0.000 1.000 1.000 1.000 1.000 0.842 ! defense response to fungus GO:0050832 21 21 0.000 1.000 1.000 1.000 1.000 0.349 ! regulation of calcium-mediated signaling GO:0050848 35 35 0.000 1.000 1.000 1.000 1.000 0.801 ! positive regulation of calcium-mediated signaling GO:0050850 24 24 0.000 1.000 1.000 1.000 1.000 0.760 ! antigen receptor-mediated signaling pathway GO:0050851 107 107 0.000 1.000 1.000 1.000 1.000 0.946 ! T cell receptor signaling pathway GO:0050852 84 84 0.000 1.000 1.000 1.000 1.000 0.946 ! B cell receptor signaling pathway GO:0050853 27 27 0.000 1.000 1.000 1.000 1.000 0.694 ! regulation of T cell receptor signaling pathway GO:0050856 20 20 0.000 1.000 1.000 1.000 1.000 0.714 ! regulation of B cell activation GO:0050864 83 83 0.000 1.000 1.000 1.000 1.000 0.887 ! negative regulation of B cell activation GO:0050869 26 26 0.000 1.000 1.000 1.000 1.000 0.793 ! positive regulation of T cell activation GO:0050870 168 168 0.000 1.000 1.000 1.000 1.000 0.946 ! positive regulation of B cell activation GO:0050871 55 55 0.000 1.000 1.000 1.000 1.000 0.878 ! detection of chemical stimulus involved in sensory perception GO:0050907 60 60 0.000 1.000 1.000 1.000 1.000 0.00429 ! detection of chemical stimulus involved in sensory perception of smell GO:0050911 36 36 0.000 1.000 1.000 1.000 1.000 0.000858 ! detection of chemical stimulus involved in sensory perception of taste GO:0050912 22 22 0.000 1.000 1.000 1.000 1.000 0.256 ! positive chemotaxis GO:0050918 24 24 0.000 1.000 1.000 1.000 1.000 0.794 ! negative regulation of chemotaxis GO:0050922 22 22 0.000 1.000 1.000 1.000 1.000 0.819 ! regulation of positive chemotaxis GO:0050926 24 24 0.000 1.000 1.000 1.000 1.000 0.774 ! positive regulation of positive chemotaxis GO:0050927 23 23 0.000 1.000 1.000 1.000 1.000 0.770 ! regulation of lipid catabolic process GO:0050994 42 42 0.000 1.000 1.000 1.000 1.000 0.870 ! regulation of nitric-oxide synthase activity GO:0050999 35 35 0.000 1.000 1.000 1.000 1.000 0.818 ! regulation of lipoprotein lipase activity GO:0051004 28 28 0.000 1.000 1.000 1.000 1.000 0.832 ! actin filament bundle assembly GO:0051017 38 38 0.000 1.000 1.000 1.000 1.000 0.711 ! negative regulation of DNA metabolic process GO:0051053 63 63 0.000 1.000 1.000 1.000 1.000 0.855 ! positive regulation of DNA metabolic process GO:0051054 100 100 0.000 1.000 1.000 1.000 1.000 0.889 ! negative regulation of small GTPase mediated signal transduction GO:0051058 31 31 0.000 1.000 1.000 1.000 1.000 0.606 ! 'de novo' posttranslational protein folding GO:0051084 49 49 0.000 1.000 1.000 1.000 1.000 0.203 ! positive regulation of striated muscle cell differentiation GO:0051155 21 21 0.000 1.000 1.000 1.000 1.000 0.779 ! vitamin transport GO:0051180 22 22 0.000 1.000 1.000 1.000 1.000 0.612 ! cofactor transport GO:0051181 21 21 0.000 1.000 1.000 1.000 1.000 0.648 ! cofactor catabolic process GO:0051187 42 42 0.000 1.000 1.000 1.000 1.000 0.837 ! cofactor biosynthetic process GO:0051188 137 137 0.000 1.000 1.000 1.000 1.000 0.946 ! cytoplasmic sequestering of protein GO:0051220 20 20 0.000 1.000 1.000 1.000 1.000 0.704 ! spindle assembly GO:0051225 40 40 0.000 1.000 1.000 1.000 1.000 0.641 ! establishment of spindle localization GO:0051293 23 22 0.000 1.000 1.000 1.000 1.000 0.709 ! centrosome organization GO:0051297 51 51 0.000 1.000 1.000 1.000 1.000 0.651 ! G1 phase GO:0051318 48 48 0.000 1.000 1.000 1.000 1.000 0.669 ! prophase GO:0051324 25 25 0.000 1.000 1.000 1.000 1.000 0.589 ! negative regulation of ligase activity GO:0051352 72 72 0.000 1.000 1.000 1.000 1.000 0.838 GO:0051444|negative regulation of ubiquitin-protein ligase activity, ! positive regulation of oxidoreductase activity GO:0051353 32 32 0.000 1.000 1.000 1.000 1.000 0.864 ! negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle GO:0051436 67 67 0.000 1.000 1.000 1.000 1.000 0.826 ! negative regulation of ubiquitin-protein ligase activity GO:0051444 72 72 0.000 1.000 1.000 1.000 1.000 0.838 GO:0051352|negative regulation of ligase activity, ! regulation of meiotic cell cycle GO:0051445 24 24 0.000 1.000 1.000 1.000 1.000 0.733 ! regulation of intracellular pH GO:0051453 23 23 0.000 1.000 1.000 1.000 1.000 0.735 ! regulation of filopodium assembly GO:0051489 33 31 0.000 1.000 1.000 1.000 1.000 0.751 ! positive regulation of filopodium assembly GO:0051491 24 22 0.000 1.000 1.000 1.000 1.000 0.696 ! establishment of vesicle localization GO:0051650 57 57 0.000 1.000 1.000 1.000 1.000 0.820 ! spindle localization GO:0051653 25 24 0.000 1.000 1.000 1.000 1.000 0.733 ! actin filament capping GO:0051693 24 24 0.000 1.000 1.000 1.000 1.000 0.592 ! interaction with symbiont GO:0051702 30 30 0.000 1.000 1.000 1.000 1.000 0.838 ! entry into cell of other organism involved in symbiotic interaction GO:0051806 21 21 0.000 1.000 1.000 1.000 1.000 0.742 GO:0044409|entry into host, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0030260|entry into host cell, GO:0052126|movement in host environment, ! modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 44 44 0.000 1.000 1.000 1.000 1.000 0.874 GO:0035821|modification of morphology or physiology of other organism, ! entry into other organism involved in symbiotic interaction GO:0051828 21 21 0.000 1.000 1.000 1.000 1.000 0.742 GO:0044409|entry into host, GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0030260|entry into host cell, GO:0052126|movement in host environment, ! modification by host of symbiont morphology or physiology GO:0051851 25 25 0.000 1.000 1.000 1.000 1.000 0.814 ! movement in host environment GO:0052126 21 21 0.000 1.000 1.000 1.000 1.000 0.742 GO:0044409|entry into host, GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0052192|movement in environment of other organism involved in symbiotic interaction, GO:0030260|entry into host cell, ! movement in environment of other organism involved in symbiotic interaction GO:0052192 21 21 0.000 1.000 1.000 1.000 1.000 0.742 GO:0044409|entry into host, GO:0051806|entry into cell of other organism involved in symbiotic interaction, GO:0051828|entry into other organism involved in symbiotic interaction, GO:0030260|entry into host cell, GO:0052126|movement in host environment, ! modulation of transcription in other organism involved in symbiotic interaction GO:0052312 21 21 0.000 1.000 1.000 1.000 1.000 0.781 ! modulation by host of symbiont transcription GO:0052472 20 20 0.000 1.000 1.000 1.000 1.000 0.769 GO:0043921|modulation by host of viral transcription, ! canonical Wnt receptor signaling pathway GO:0060070 85 85 0.000 1.000 1.000 1.000 1.000 0.884 ! Wnt receptor signaling pathway, planar cell polarity pathway GO:0060071 21 21 0.000 1.000 1.000 1.000 1.000 0.793 GO:0090175|regulation of establishment of planar polarity, ! inner ear receptor cell differentiation GO:0060113 43 43 0.000 1.000 1.000 1.000 1.000 0.814 ! inner ear receptor cell development GO:0060119 24 24 0.000 1.000 1.000 1.000 1.000 0.750 ! maternal process involved in female pregnancy GO:0060135 20 20 0.000 1.000 1.000 1.000 1.000 0.733 ! regulation of response to interferon-gamma GO:0060330 25 25 0.000 1.000 1.000 1.000 1.000 0.734 ! regulation of interferon-gamma-mediated signaling pathway GO:0060334 24 24 0.000 1.000 1.000 1.000 1.000 0.749 ! regulation of type I interferon-mediated signaling pathway GO:0060338 34 34 0.000 1.000 1.000 1.000 1.000 0.581 ! JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 24 24 0.000 1.000 1.000 1.000 1.000 0.738 ! lung epithelium development GO:0060428 26 26 0.000 1.000 1.000 1.000 1.000 0.818 ! branching involved in mammary gland duct morphogenesis GO:0060444 23 23 0.000 1.000 1.000 1.000 1.000 0.824 ! regulation of cell projection assembly GO:0060491 61 58 0.000 1.000 1.000 1.000 1.000 0.844 ! positive regulation of response to cytokine stimulus GO:0060760 20 20 0.000 1.000 1.000 1.000 1.000 0.791 ! regulation of androgen receptor signaling pathway GO:0060765 22 22 0.000 1.000 1.000 1.000 1.000 0.755 ! regulation of gene silencing GO:0060968 21 21 0.000 1.000 1.000 1.000 1.000 0.714 ! regulation of dendritic spine development GO:0060998 25 25 0.000 1.000 1.000 1.000 1.000 0.792 ! hepaticobiliary system development GO:0061008 80 80 0.000 1.000 1.000 1.000 1.000 0.883 ! regulation of wound healing GO:0061041 81 81 0.000 1.000 1.000 1.000 1.000 0.887 ! chaperone-mediated protein folding GO:0061077 24 24 0.000 1.000 1.000 1.000 1.000 0.402 ! regulation of proteasomal protein catabolic process GO:0061136 66 66 0.000 1.000 1.000 1.000 1.000 0.842 ! regulation of insulin secretion involved in cellular response to glucose stimulus GO:0061178 28 28 0.000 1.000 1.000 1.000 1.000 0.799 ! establishment or maintenance of bipolar cell polarity GO:0061245 21 21 0.000 1.000 1.000 1.000 1.000 0.707 GO:0035088|establishment or maintenance of apical/basal cell polarity, ! renal tubule development GO:0061326 33 33 0.000 1.000 1.000 1.000 1.000 0.874 ! renal tubule morphogenesis GO:0061333 22 22 0.000 1.000 1.000 1.000 1.000 0.845 ! determination of heart left/right asymmetry GO:0061371 47 47 0.000 1.000 1.000 1.000 1.000 0.874 ! protein trimerization GO:0070206 30 30 0.000 1.000 1.000 1.000 1.000 0.624 ! regulation of lymphocyte apoptosis GO:0070228 31 31 0.000 1.000 1.000 1.000 1.000 0.841 ! triglyceride homeostasis GO:0070328 23 23 0.000 1.000 1.000 1.000 1.000 0.769 ! protein K63-linked ubiquitination GO:0070534 25 25 0.000 1.000 1.000 1.000 1.000 0.643 ! protein localization in mitochondrion GO:0070585 58 57 0.000 1.000 1.000 1.000 1.000 0.679 ! calcium ion transmembrane transport GO:0070588 31 31 0.000 1.000 1.000 1.000 1.000 0.812 ! regulation of protein processing GO:0070613 43 43 0.000 1.000 1.000 1.000 1.000 0.770 ! leukocyte proliferation GO:0070661 57 57 0.000 1.000 1.000 1.000 1.000 0.864 ! negative regulation of leukocyte proliferation GO:0070664 56 56 0.000 1.000 1.000 1.000 1.000 0.866 ! tight junction assembly GO:0070830 32 32 0.000 1.000 1.000 1.000 1.000 0.459 ! regulation of glycogen metabolic process GO:0070873 31 31 0.000 1.000 1.000 1.000 1.000 0.834 ! organelle assembly GO:0070925 104 103 0.000 1.000 1.000 1.000 1.000 0.946 ! protein K48-linked ubiquitination GO:0070936 37 37 0.000 1.000 1.000 1.000 1.000 0.384 ! protein K11-linked ubiquitination GO:0070979 26 26 0.000 1.000 1.000 1.000 1.000 0.526 ! positive regulation of cell cycle arrest GO:0071158 80 80 0.000 1.000 1.000 1.000 1.000 0.850 ! cellular response to acid GO:0071229 44 41 0.000 1.000 1.000 1.000 1.000 0.745 ! cellular response to amino acid stimulus GO:0071230 38 35 0.000 1.000 1.000 1.000 1.000 0.711 ! cellular response to cAMP GO:0071320 22 22 0.000 1.000 1.000 1.000 1.000 0.806 ! cellular response to monosaccharide stimulus GO:0071326 28 28 0.000 1.000 1.000 1.000 1.000 0.816 GO:0071333|cellular response to glucose stimulus, GO:0071331|cellular response to hexose stimulus, ! cellular response to hexose stimulus GO:0071331 28 28 0.000 1.000 1.000 1.000 1.000 0.816 GO:0071326|cellular response to monosaccharide stimulus, GO:0071333|cellular response to glucose stimulus, ! cellular response to glucose stimulus GO:0071333 28 28 0.000 1.000 1.000 1.000 1.000 0.816 GO:0071326|cellular response to monosaccharide stimulus, GO:0071331|cellular response to hexose stimulus, ! cellular response to interleukin-1 GO:0071347 39 39 0.000 1.000 1.000 1.000 1.000 0.865 ! cellular response to tumor necrosis factor GO:0071356 67 66 0.000 1.000 1.000 1.000 1.000 0.865 ! cellular response to dsRNA GO:0071359 22 21 0.000 1.000 1.000 1.000 1.000 0.720 ! cellular response to ionizing radiation GO:0071479 33 32 0.000 1.000 1.000 1.000 1.000 0.772 ! cellular response to transforming growth factor beta stimulus GO:0071560 30 30 0.000 1.000 1.000 1.000 1.000 0.810 ! acyl-CoA biosynthetic process GO:0071616 20 20 0.000 1.000 1.000 1.000 1.000 0.724 GO:0035384|thioester biosynthetic process, GO:0046949|fatty-acyl-CoA biosynthetic process, ! G1/S transition checkpoint GO:0071779 84 84 0.000 1.000 1.000 1.000 1.000 0.946 ! DNA biosynthetic process GO:0071897 20 20 0.000 1.000 1.000 1.000 1.000 0.596 ! nephron epithelium development GO:0072009 41 41 0.000 1.000 1.000 1.000 1.000 0.883 ! nephron morphogenesis GO:0072028 31 31 0.000 1.000 1.000 1.000 1.000 0.874 ! nephron tubule development GO:0072080 32 32 0.000 1.000 1.000 1.000 1.000 0.872 ! nephron epithelium morphogenesis GO:0072088 28 28 0.000 1.000 1.000 1.000 1.000 0.865 ! metanephric nephron development GO:0072210 32 32 0.000 1.000 1.000 1.000 1.000 0.881 ! metanephric nephron morphogenesis GO:0072273 21 21 0.000 1.000 1.000 1.000 1.000 0.860 ! signal transduction by p53 class mediator GO:0072331 115 114 0.000 1.000 1.000 1.000 1.000 0.946 ! signal transduction by p53 class mediator resulting in induction of apoptosis GO:0072332 34 33 0.000 1.000 1.000 1.000 1.000 0.760 ! protein activation cascade GO:0072376 70 70 0.000 1.000 1.000 1.000 1.000 0.667 ! blood coagulation, fibrin clot formation GO:0072378 21 21 0.000 1.000 1.000 1.000 1.000 0.576 ! signal transduction involved in cell cycle checkpoint GO:0072395 68 68 0.000 1.000 1.000 1.000 1.000 0.826 ! signal transduction involved in DNA integrity checkpoint GO:0072401 67 67 0.000 1.000 1.000 1.000 1.000 0.823 GO:0072422|signal transduction involved in DNA damage checkpoint, ! signal transduction involved in G1/S transition checkpoint GO:0072404 67 67 0.000 1.000 1.000 1.000 1.000 0.825 ! signal transduction involved in mitotic cell cycle checkpoint GO:0072413 66 66 0.000 1.000 1.000 1.000 1.000 0.820 GO:0072474|signal transduction involved in mitotic cell cycle G1/S checkpoint, GO:0006977|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, GO:0072431|signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint, ! signal transduction involved in DNA damage checkpoint GO:0072422 67 67 0.000 1.000 1.000 1.000 1.000 0.823 GO:0072401|signal transduction involved in DNA integrity checkpoint, ! signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint GO:0072431 66 66 0.000 1.000 1.000 1.000 1.000 0.820 GO:0072474|signal transduction involved in mitotic cell cycle G1/S checkpoint, GO:0006977|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, GO:0072413|signal transduction involved in mitotic cell cycle checkpoint, ! signal transduction involved in mitotic cell cycle G1/S checkpoint GO:0072474 66 66 0.000 1.000 1.000 1.000 1.000 0.820 GO:0006977|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, GO:0072413|signal transduction involved in mitotic cell cycle checkpoint, GO:0072431|signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint, ! pyridine-containing compound metabolic process GO:0072524 49 49 0.000 1.000 1.000 1.000 1.000 0.837 ! pyrimidine-containing compound metabolic process GO:0072527 70 70 0.000 1.000 1.000 1.000 1.000 0.875 ! pyrimidine-containing compound biosynthetic process GO:0072528 38 38 0.000 1.000 1.000 1.000 1.000 0.843 ! pyrimidine-containing compound catabolic process GO:0072529 31 31 0.000 1.000 1.000 1.000 1.000 0.795 ! maintenance of protein localization to organelle GO:0072595 23 23 0.000 1.000 1.000 1.000 1.000 0.625 ! establishment of protein localization in mitochondrion GO:0072655 57 56 0.000 1.000 1.000 1.000 1.000 0.674 ! establishment of protein localization in plasma membrane GO:0090002 24 24 0.000 1.000 1.000 1.000 1.000 0.735 ! regulation of establishment of protein localization in plasma membrane GO:0090003 24 24 0.000 1.000 1.000 1.000 1.000 0.774 ! regulation of neutrophil chemotaxis GO:0090022 20 20 0.000 1.000 1.000 1.000 1.000 0.808 ! cochlea morphogenesis GO:0090103 21 21 0.000 1.000 1.000 1.000 1.000 0.808 ! establishment of protein localization in membrane GO:0090150 26 26 0.000 1.000 1.000 1.000 1.000 0.752 ! regulation of establishment of planar polarity GO:0090175 21 21 0.000 1.000 1.000 1.000 1.000 0.793 GO:0060071|Wnt receptor signaling pathway, planar cell polarity pathway, ! regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 22 0.000 1.000 1.000 1.000 1.000 0.815 ! regulation of release of cytochrome c from mitochondria GO:0090199 32 32 0.000 1.000 1.000 1.000 1.000 0.804 ! positive regulation of release of cytochrome c from mitochondria GO:0090200 22 22 0.000 1.000 1.000 1.000 1.000 0.710 ! regulation of DNA-dependent DNA replication GO:0090329 26 26 0.000 1.000 1.000 1.000 1.000 0.792 ! cellular senescence GO:0090398 28 28 0.000 1.000 1.000 1.000 1.000 0.808 ! regulation of hemostasis GO:1900046 61 61 0.000 1.000 1.000 1.000 1.000 0.872 GO:0030193|regulation of blood coagulation, ! negative regulation of hemostasis GO:1900047 36 36 0.000 1.000 1.000 1.000 1.000 0.796 GO:0030195|negative regulation of blood coagulation, ! regulation of cellular response to insulin stimulus GO:1900076 37 36 0.000 1.000 1.000 1.000 1.000 0.847 ! negative regulation of cellular response to insulin stimulus GO:1900077 23 23 0.000 1.000 1.000 1.000 1.000 0.804 ! regulation of G1/S transition of mitotic cell cycle GO:2000045 103 103 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of leukocyte apoptosis GO:2000106 45 45 0.000 1.000 1.000 1.000 1.000 0.875 ! negative regulation of leukocyte apoptosis GO:2000107 27 27 0.000 1.000 1.000 1.000 1.000 0.844 ! regulation of fatty acid transport GO:2000191 22 22 0.000 1.000 1.000 1.000 1.000 0.828 ! positive regulation of reproductive process GO:2000243 99 95 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of protein activation cascade GO:2000257 20 20 0.000 1.000 1.000 1.000 1.000 0.524 GO:0030449|regulation of complement activation, ! regulation of reactive oxygen species metabolic process GO:2000377 57 57 0.000 1.000 1.000 1.000 1.000 0.863 ! positive regulation of reactive oxygen species metabolic process GO:2000379 32 32 0.000 1.000 1.000 1.000 1.000 0.832 ! regulation of lymphocyte migration GO:2000401 22 21 0.000 1.000 1.000 1.000 1.000 0.794 ! regulation of CD4-positive, alpha-beta T cell activation GO:2000514 30 30 0.000 1.000 1.000 1.000 1.000 0.863 ! regulation of interphase of mitotic cell cycle GO:2000602 157 157 0.000 1.000 1.000 1.000 1.000 0.946 ! regulation of response to DNA damage stimulus GO:2001020 85 85 0.000 1.000 1.000 1.000 1.000 0.871 ! positive regulation of response to DNA damage stimulus GO:2001022 46 46 0.000 1.000 1.000 1.000 1.000 0.813 ! regulation of intrinsic apoptotic signaling pathway GO:2001242 24 24 0.000 1.000 1.000 1.000 1.000 0.776 !#====== End run =======